BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 36982731)

  • 1. BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis.
    Perez-Serna AA; Dos Santos RS; Ripoll C; Nadal A; Eizirik DL; Marroqui L
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982731
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor.
    Yang Y; Tong Y; Gong M; Lu Y; Wang C; Zhou M; Yang Q; Mao T; Tong N
    Cell Signal; 2014 Feb; 26(2):268-78. PubMed ID: 24269940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis.
    Allagnat F; Cunha D; Moore F; Vanderwinden JM; Eizirik DL; Cardozo AK
    Cell Death Differ; 2011 Feb; 18(2):328-37. PubMed ID: 20798690
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.
    Tsonkova VG; Sand FW; Wolf XA; Grunnet LG; Kirstine Ringgaard A; Ingvorsen C; Winkel L; Kalisz M; Dalgaard K; Bruun C; Fels JJ; Helgstrand C; Hastrup S; Öberg FK; Vernet E; Sandrini MPB; Shaw AC; Jessen C; Grønborg M; Hald J; Willenbrock H; Madsen D; Wernersson R; Hansson L; Jensen JN; Plesner A; Alanentalo T; Petersen MBK; Grapin-Botton A; Honoré C; Ahnfelt-Rønne J; Hecksher-Sørensen J; Ravassard P; Madsen OD; Rescan C; Frogne T
    Mol Metab; 2018 Feb; 8():144-157. PubMed ID: 29307512
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine.
    Ngamjariyawat A; Cen J; Said R; Incedal C; Idevall-Hagren O; Welsh N
    Front Endocrinol (Lausanne); 2023; 14():1060675. PubMed ID: 36761184
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
    Oshima M; Pechberty S; Bellini L; Göpel SO; Campana M; Rouch C; Dairou J; Cosentino C; Fantuzzi F; Toivonen S; Marchetti P; Magnan C; Cnop M; Le Stunff H; Scharfmann R
    Diabetologia; 2020 Feb; 63(2):395-409. PubMed ID: 31796987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct differences in the responses of the human pancreatic β-cell line EndoC-βH1 and human islets to proinflammatory cytokines.
    Oleson BJ; McGraw JA; Broniowska KA; Annamalai M; Chen J; Bushkofsky JR; Davis DB; Corbett JA; Mathews CE
    Am J Physiol Regul Integr Comp Physiol; 2015 Sep; 309(5):R525-34. PubMed ID: 26084699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response.
    Sommerweiss D; Gorski T; Richter S; Garten A; Kiess W
    Biochem Biophys Res Commun; 2013 Nov; 441(4):770-6. PubMed ID: 24189472
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance.
    Miani M; Barthson J; Colli ML; Brozzi F; Cnop M; Eizirik DL
    Cell Death Dis; 2013 Jul; 4(7):e701. PubMed ID: 23828564
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells.
    Thomas P; Arden C; Corcoran J; Hacker C; Welters HJ; Morgan NG
    Nutr Diabetes; 2022 Apr; 12(1):22. PubMed ID: 35443738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction.
    Kim M; Lee JS; Oh JE; Nan J; Lee H; Jung HS; Chung SS; Park KS
    PLoS One; 2015; 10(4):e0124744. PubMed ID: 25915406
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sterol regulatory element-binding protein-1c knockdown protected INS-1E cells from lipotoxicity.
    Li J; Liu X; Ran X; Chen J; Li X; Wu W; Huang H; Huang H; Long Y; Liang J; Cheng J; Tian H
    Diabetes Obes Metab; 2010 Jan; 12(1):35-46. PubMed ID: 19758361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.
    Allagnat F; Klee P; Cardozo AK; Meda P; Haefliger JA
    Cell Death Differ; 2013 Dec; 20(12):1742-52. PubMed ID: 24096873
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.
    Akerfeldt MC; Howes J; Chan JY; Stevens VA; Boubenna N; McGuire HM; King C; Biden TJ; Laybutt DR
    Diabetes; 2008 Nov; 57(11):3034-44. PubMed ID: 18591394
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sirtuin 5 overexpression attenuates glucolipotoxicity-induced pancreatic β cells apoptosis and dysfunction.
    Wang Y; Liu Q; Huan Y; Li R; Li C; Sun S; Guo N; Yang M; Liu S; Shen Z
    Exp Cell Res; 2018 Oct; 371(1):205-213. PubMed ID: 30098330
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.
    Kharroubi I; Ladrière L; Cardozo AK; Dogusan Z; Cnop M; Eizirik DL
    Endocrinology; 2004 Nov; 145(11):5087-96. PubMed ID: 15297438
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine.
    Ngamjariyawat A; Cen J; Wang X; Welsh N
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38255875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.
    Brozzi F; Nardelli TR; Lopes M; Millard I; Barthson J; Igoillo-Esteve M; Grieco FA; Villate O; Oliveira JM; Casimir M; Bugliani M; Engin F; Hotamisligil GS; Marchetti P; Eizirik DL
    Diabetologia; 2015 Oct; 58(10):2307-16. PubMed ID: 26099855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation.
    Barlow J; Solomon TPJ; Affourtit C
    PLoS One; 2018; 13(6):e0199505. PubMed ID: 29953508
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines.
    Gurgul-Convey E; Mehmeti I; Plötz T; Jörns A; Lenzen S
    Diabetologia; 2016 Oct; 59(10):2125-33. PubMed ID: 27460666
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.