209 related articles for article (PubMed ID: 36996677)
1. Research progress of indole-fused derivatives as allosteric modulators: Opportunities for drug development.
Luo ML; Zhao Q; He XH; Xie X; Zhu HP; You FM; Peng C; Zhan G; Huang W
Biomed Pharmacother; 2023 Jun; 162():114574. PubMed ID: 36996677
[TBL] [Abstract][Full Text] [Related]
2. Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.
Lu S; He X; Ni D; Zhang J
J Med Chem; 2019 Jul; 62(14):6405-6421. PubMed ID: 30817889
[TBL] [Abstract][Full Text] [Related]
3. Allosteric modulation of GPCRs: From structural insights to in silico drug discovery.
Persechino M; Hedderich JB; Kolb P; Hilger D
Pharmacol Ther; 2022 Sep; 237():108242. PubMed ID: 35863587
[TBL] [Abstract][Full Text] [Related]
4. Harnessing allostery: a novel approach to drug discovery.
Lu S; Li S; Zhang J
Med Res Rev; 2014 Nov; 34(6):1242-85. PubMed ID: 24827416
[TBL] [Abstract][Full Text] [Related]
5. Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors.
Feng Z; Hu G; Ma S; Xie XQ
AAPS J; 2015 Sep; 17(5):1080-95. PubMed ID: 25940084
[TBL] [Abstract][Full Text] [Related]
6. Allosteric Methods and Their Applications: Facilitating the Discovery of Allosteric Drugs and the Investigation of Allosteric Mechanisms.
Lu S; Shen Q; Zhang J
Acc Chem Res; 2019 Feb; 52(2):492-500. PubMed ID: 30688063
[TBL] [Abstract][Full Text] [Related]
7. Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
Bartuzi D; Kaczor AA; Matosiuk D
Methods Mol Biol; 2018; 1705():297-319. PubMed ID: 29188568
[TBL] [Abstract][Full Text] [Related]
8. Computational Tools for Allosteric Drug Discovery: Site Identification and Focus Library Design.
Huang W; Nussinov R; Zhang J
Methods Mol Biol; 2017; 1529():439-446. PubMed ID: 27914066
[TBL] [Abstract][Full Text] [Related]
9. Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.
Keov P; Sexton PM; Christopoulos A
Neuropharmacology; 2011 Jan; 60(1):24-35. PubMed ID: 20637785
[TBL] [Abstract][Full Text] [Related]
10. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.
Janero DR; Thakur GA
Expert Opin Drug Discov; 2016 Dec; 11(12):1223-1237. PubMed ID: 27712124
[TBL] [Abstract][Full Text] [Related]
11. Allosteric modulators of G-protein-coupled receptors.
May LT; Christopoulos A
Curr Opin Pharmacol; 2003 Oct; 3(5):551-6. PubMed ID: 14559102
[TBL] [Abstract][Full Text] [Related]
12. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
Burford NT; Watson J; Bertekap R; Alt A
Biochem Pharmacol; 2011 Mar; 81(6):691-702. PubMed ID: 21184747
[TBL] [Abstract][Full Text] [Related]
13. Toward understanding the molecular basis for chemical allosteric modulator design.
Wang Q; Zheng M; Huang Z; Liu X; Zhou H; Chen Y; Shi T; Zhang J
J Mol Graph Model; 2012 Sep; 38():324-33. PubMed ID: 23085171
[TBL] [Abstract][Full Text] [Related]
14. Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?
An X; Lu S; Song K; Shen Q; Huang M; Yao X; Liu H; Zhang J
J Chem Inf Model; 2019 Jan; 59(1):597-604. PubMed ID: 30525607
[TBL] [Abstract][Full Text] [Related]
15. Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery.
Mantione E; Micheloni S; Alcaino C; New K; Mazzaferro S; Bermudez I
Future Med Chem; 2012 Nov; 4(17):2217-30. PubMed ID: 23190109
[TBL] [Abstract][Full Text] [Related]
16. Allosteric modulation of G protein-coupled receptors.
May LT; Leach K; Sexton PM; Christopoulos A
Annu Rev Pharmacol Toxicol; 2007; 47():1-51. PubMed ID: 17009927
[TBL] [Abstract][Full Text] [Related]
17. Identifying novel modulators of G protein-coupled receptors via interaction at allosteric sites.
Presland J
Curr Opin Drug Discov Devel; 2005 Sep; 8(5):567-76. PubMed ID: 16159018
[TBL] [Abstract][Full Text] [Related]
18. How Do Modulators Affect the Orthosteric and Allosteric Binding Pockets?
Chen CJ; Jiang C; Yuan J; Chen M; Cuyler J; Xie XQ; Feng Z
ACS Chem Neurosci; 2022 Apr; 13(7):959-977. PubMed ID: 35298129
[TBL] [Abstract][Full Text] [Related]
19. Integrated In Silico Fragment-Based Drug Design: Case Study with Allosteric Modulators on Metabotropic Glutamate Receptor 5.
Bian Y; Feng Z; Yang P; Xie XQ
AAPS J; 2017 Jul; 19(4):1235-1248. PubMed ID: 28560482
[TBL] [Abstract][Full Text] [Related]
20. Current and Future Challenges in GPCR Drug Discovery.
Topiol S
Methods Mol Biol; 2018; 1705():1-21. PubMed ID: 29188556
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
