BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 36997727)

  • 21. Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells.
    Nikinmaa M; Pursiheimo S; Soitamo AJ
    J Cell Sci; 2004 Jul; 117(Pt 15):3201-6. PubMed ID: 15199099
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.
    Liu YV; Hubbi ME; Pan F; McDonald KR; Mansharamani M; Cole RN; Liu JO; Semenza GL
    J Biol Chem; 2007 Dec; 282(51):37064-73. PubMed ID: 17965024
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells.
    Zhou J; Zhang S; Xue J; Avery J; Wu J; Lind SE; Ding WQ
    J Biol Chem; 2012 Oct; 287(42):35161-35169. PubMed ID: 22932900
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.
    Han JY; Oh SH; Morgillo F; Myers JN; Kim E; Hong WK; Lee HY
    J Natl Cancer Inst; 2005 Sep; 97(17):1272-86. PubMed ID: 16145048
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
    André H; Pereira TS
    J Biol Chem; 2008 Oct; 283(43):29375-84. PubMed ID: 18694926
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha.
    Luo W; Zhong J; Chang R; Hu H; Pandey A; Semenza GL
    J Biol Chem; 2010 Feb; 285(6):3651-3663. PubMed ID: 19940151
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.
    Park SS; Bae I; Lee YJ
    J Cell Biochem; 2008 Apr; 103(6):1989-98. PubMed ID: 17973296
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TARBP2 Suppresses Ubiquitin-Proteasomal Degradation of HIF-1α in Breast Cancer.
    Li JN; Chen PS; Chiu CF; Lyu YJ; Lo C; Tsai LW; Wang MY
    Int J Mol Sci; 2021 Dec; 23(1):. PubMed ID: 35008634
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins.
    Srinivas V; Zhang LP; Zhu XH; Caro J
    Biochem Biophys Res Commun; 1999 Jul; 260(2):557-61. PubMed ID: 10403805
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
    Foxler DE; Bridge KS; James V; Webb TM; Mee M; Wong SC; Feng Y; Constantin-Teodosiu D; Petursdottir TE; Bjornsson J; Ingvarsson S; Ratcliffe PJ; Longmore GD; Sharp TV
    Nat Cell Biol; 2012 Jan; 14(2):201-8. PubMed ID: 22286099
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect.
    Lee WH; Kim YW; Choi JH; Brooks SC; Lee MO; Kim SG
    Mol Cancer Ther; 2009 Oct; 8(10):2791-802. PubMed ID: 19789218
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Modulation of glucose metabolism inhibits hypoxic accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha).
    Staab A; Löffler J; Said HM; Katzer A; Beyer M; Polat B; Einsele H; Flentje M; Vordermark D
    Strahlenther Onkol; 2007 Jul; 183(7):366-73. PubMed ID: 17609869
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Kaposi's sarcoma-associated herpesvirus ORF34 protein binds to HIF-1α and causes its degradation via the proteasome pathway.
    Haque M; Kousoulas KG
    J Virol; 2013 Feb; 87(4):2164-73. PubMed ID: 23221556
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
    Tammali R; Saxena A; Srivastava SK; Ramana KV
    J Biol Chem; 2011 Jul; 286(27):24089-100. PubMed ID: 21576240
    [TBL] [Abstract][Full Text] [Related]  

  • 37. p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).
    Schmid T; Zhou J; Köhl R; Brüne B
    Biochem J; 2004 May; 380(Pt 1):289-95. PubMed ID: 14992692
    [TBL] [Abstract][Full Text] [Related]  

  • 38. RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells.
    Lee SH; Bae SC; Kim KW; Lee YM
    Oncogene; 2014 Mar; 33(11):1458-67. PubMed ID: 23542169
    [TBL] [Abstract][Full Text] [Related]  

  • 39. LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line.
    Lee K; Kang JE; Park SK; Jin Y; Chung KS; Kim HM; Lee K; Kang MR; Lee MK; Song KB; Yang EG; Lee JJ; Won M
    Biochem Pharmacol; 2010 Oct; 80(7):982-9. PubMed ID: 20599784
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.
    Callapina M; Zhou J; Schnitzer S; Metzen E; Lohr C; Deitmer JW; Brüne B
    Exp Cell Res; 2005 May; 306(1):274-84. PubMed ID: 15878351
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.