138 related articles for article (PubMed ID: 36998144)
1. Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle.
Kapoor S; Chatterjee DR; Chowdhury MG; Das R; Shard A
Curr Drug Targets; 2023; 24(6):464-483. PubMed ID: 36998144
[TBL] [Abstract][Full Text] [Related]
2. Integrated In Silico-In Vitro Discovery of Lung Cancer-related Tumor Pyruvate Kinase M2 (PKM2) Inhibitors.
Ye X; Sun Y; Xu Y; Chen Z; Lu S
Med Chem; 2016; 12(7):613-620. PubMed ID: 26951145
[TBL] [Abstract][Full Text] [Related]
3. Structure-Guided Approach to Discover Tuberosin as a Potent Activator of Pyruvate Kinase M2, Targeting Cancer Therapy.
Adnan M; Shamsi A; Elasbali AM; Siddiqui AJ; Patel M; Alshammari N; Alharethi SH; Alhassan HH; Bardakci F; Hassan MI
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361954
[TBL] [Abstract][Full Text] [Related]
4. Design, Synthesis and Biological Evaluation of Quinoline-8-Sulfonamides as Inhibitors of the Tumor Cell-Specific M2 Isoform of Pyruvate Kinase: Preliminary Study.
Marciniec K; Rzepka Z; Chrobak E; Boryczka S; Latocha M; Wrześniok D; Beberok A
Molecules; 2023 Mar; 28(6):. PubMed ID: 36985481
[TBL] [Abstract][Full Text] [Related]
5. Molecular simulation of Tyr105 phosphorylated pyruvate kinase M2 to understand its structure and dynamics.
Kalaiarasan P; Subbarao N; Bamezai RN
J Mol Model; 2014 Sep; 20(9):2447. PubMed ID: 25208557
[TBL] [Abstract][Full Text] [Related]
6. 2'-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2.
Yoon YJ; Kim YH; Jin Y; Chi SW; Moon JH; Han DC; Kwon BM
Cancer Lett; 2018 Oct; 434():42-55. PubMed ID: 30009856
[TBL] [Abstract][Full Text] [Related]
7. Pyruvate kinase M2 and cancer: an updated assessment.
Iqbal MA; Gupta V; Gopinath P; Mazurek S; Bamezai RN
FEBS Lett; 2014 Aug; 588(16):2685-92. PubMed ID: 24747424
[TBL] [Abstract][Full Text] [Related]
8. Identification of a new pyruvate kinase M2 isoform (PKM2) activator for the treatment of non-small-cell lung cancer (NSCLC).
Li RZ; Fan XX; Shi DF; Zhu GY; Wang YW; Luo LX; Pan HD; Yao XJ; Leung EL; Liu L
Chem Biol Drug Des; 2018 Nov; 92(5):1851-1858. PubMed ID: 29931766
[TBL] [Abstract][Full Text] [Related]
9. M-Type Pyruvate Kinase Isoforms and Lactate Dehydrogenase A in the Mammalian Retina: Metabolic Implications.
Casson RJ; Wood JP; Han G; Kittipassorn T; Peet DJ; Chidlow G
Invest Ophthalmol Vis Sci; 2016 Jan; 57(1):66-80. PubMed ID: 26780311
[TBL] [Abstract][Full Text] [Related]
10. A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy.
Yang GJ; Wu J; Leung CH; Ma DL; Chen J
Int J Biol Macromol; 2021 Dec; 193(Pt B):1499-1506. PubMed ID: 34740687
[TBL] [Abstract][Full Text] [Related]
11. Computer-aided identification of a novel pyruvate kinase M2 activator compound.
Li Y; Bao M; Yang C; Chen J; Zhou S; Sun R; Wu C; Li X; Bao J
Cell Prolif; 2018 Dec; 51(6):e12509. PubMed ID: 30133040
[TBL] [Abstract][Full Text] [Related]
12. Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase.
Ning X; Qi H; Li R; Li Y; Jin Y; McNutt MA; Liu J; Yin Y
Eur J Med Chem; 2017 Sep; 138():343-352. PubMed ID: 28688274
[TBL] [Abstract][Full Text] [Related]
13. Rationalization of the activity Profile of Pyruvate Kinase Isozyme M2 (PKM2) Inhibitors using 3D QSAR.
Kusuma M; Arora S; Kalra S; Chaturvedi A; Heuser M; Kumar R
Curr Top Med Chem; 2021; 21(25):2258-2271. PubMed ID: 34348626
[TBL] [Abstract][Full Text] [Related]
14. The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs.
Puckett DL; Alquraishi M; Chowanadisai W; Bettaieb A
Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33503959
[TBL] [Abstract][Full Text] [Related]
15. Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation.
Pan Y; Wang W; Huang S; Ni W; Wei Z; Cao Y; Yu S; Jia Q; Wu Y; Chai C; Zheng Q; Zhang L; Wang A; Sun Z; Huang S; Wang S; Chen W; Lu Y
J Cell Mol Med; 2019 Oct; 23(10):6846-6858. PubMed ID: 31343107
[TBL] [Abstract][Full Text] [Related]
16. Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator.
Matsui Y; Yasumatsu I; Asahi T; Kitamura T; Kanai K; Ubukata O; Hayasaka H; Takaishi S; Hanzawa H; Katakura S
Bioorg Med Chem; 2017 Jul; 25(13):3540-3546. PubMed ID: 28511909
[TBL] [Abstract][Full Text] [Related]
17. Synergistic Allosteric Mechanism of Fructose-1,6-bisphosphate and Serine for Pyruvate Kinase M2 via Dynamics Fluctuation Network Analysis.
Yang J; Liu H; Liu X; Gu C; Luo R; Chen HF
J Chem Inf Model; 2016 Jun; 56(6):1184-1192. PubMed ID: 27227511
[TBL] [Abstract][Full Text] [Related]
18. Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors.
Dimitrijevs P; Makrecka-Kuka M; Bogucka A; Hyvönen M; Pantelejevs T; Arsenyan P
Eur J Med Chem; 2023 Sep; 257():115504. PubMed ID: 37216812
[TBL] [Abstract][Full Text] [Related]
19. Pyruvate kinase M knockdown-induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival.
Prakasam G; Singh RK; Iqbal MA; Saini SK; Tiku AB; Bamezai RNK
J Biol Chem; 2017 Sep; 292(37):15561-15576. PubMed ID: 28778925
[TBL] [Abstract][Full Text] [Related]
20. Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment.
Sarfraz I; Rasul A; Jabeen F; Sultana T; Adem Ş
Molecules; 2022 Oct; 27(20):. PubMed ID: 36296707
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
