188 related articles for article (PubMed ID: 37004354)
1. Targeted pharmacologic inhibition of S-phase kinase-associated protein 2 (SKP2) mediated cell cycle regulation in lung and other RB-Related cancers: A brief review of current status and future prospects.
Elahi AH; Morales CS; Xu XL; Eliades A; Patsalis PC; Abramson DH; Jhanwar SC
Adv Biol Regul; 2023 May; 88():100964. PubMed ID: 37004354
[TBL] [Abstract][Full Text] [Related]
2. Targeted Inhibition of the E3 Ligase SCF
Zhao H; Iqbal NJ; Sukrithan V; Nicholas C; Xue Y; Yu C; Locker J; Zou J; Schwartz EL; Zhu L
Cancer Res; 2020 Jun; 80(11):2355-2367. PubMed ID: 32265224
[TBL] [Abstract][Full Text] [Related]
3. A novel thyroid hormone receptor isoform, TRβ2-46, promotes SKP2 expression and retinoblastoma cell proliferation.
Li Z; Qi DL; Singh HP; Zou Y; Shen B; Cobrinik D
J Biol Chem; 2019 Feb; 294(8):2961-2969. PubMed ID: 30643022
[TBL] [Abstract][Full Text] [Related]
4. Genomic instability and proliferation/survival pathways in RB1-deficient malignancies.
Pappas L; Xu XL; Abramson DH; Jhanwar SC
Adv Biol Regul; 2017 May; 64():20-32. PubMed ID: 28242412
[TBL] [Abstract][Full Text] [Related]
5. An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant.
Ji P; Jiang H; Rekhtman K; Bloom J; Ichetovkin M; Pagano M; Zhu L
Mol Cell; 2004 Oct; 16(1):47-58. PubMed ID: 15469821
[TBL] [Abstract][Full Text] [Related]
6. SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells.
Xu XL; Li Z; Liu A; Fan X; Hu DN; Qi DL; Chitty DW; Jia R; Qui J; Wang JQ; Sharaf J; Zou J; Weiss R; Huang H; Joseph WJ; Ng L; Rosen R; Shen B; Reid MW; Forrest D; Abramson DH; Singer S; Cobrinik D; Jhanwar SC
Cancer Res; 2017 Dec; 77(24):6838-6850. PubMed ID: 28972075
[TBL] [Abstract][Full Text] [Related]
7. Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice.
Wang H; Bauzon F; Ji P; Xu X; Sun D; Locker J; Sellers RS; Nakayama K; Nakayama KI; Cobrinik D; Zhu L
Nat Genet; 2010 Jan; 42(1):83-8. PubMed ID: 19966802
[TBL] [Abstract][Full Text] [Related]
8. p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function.
Liu S; Yamauchi H
Cancer Lett; 2009 Dec; 286(2):240-9. PubMed ID: 19631451
[TBL] [Abstract][Full Text] [Related]
9. Rb suppresses human cone-precursor-derived retinoblastoma tumours.
Xu XL; Singh HP; Wang L; Qi DL; Poulos BK; Abramson DH; Jhanwar SC; Cobrinik D
Nature; 2014 Oct; 514(7522):385-8. PubMed ID: 25252974
[TBL] [Abstract][Full Text] [Related]
10. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
[TBL] [Abstract][Full Text] [Related]
11. p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer.
Zhao H; Lu Z; Bauzon F; Fu H; Cui J; Locker J; Zhu L
Oncogene; 2017 Jan; 36(1):60-70. PubMed ID: 27181203
[TBL] [Abstract][Full Text] [Related]
12. Down-regulation of SKP2 induces apoptosis in lung-cancer cells.
Yokoi S; Yasui K; Iizasa T; Takahashi T; Fujisawa T; Inazawa J
Cancer Sci; 2003 Apr; 94(4):344-9. PubMed ID: 12824902
[TBL] [Abstract][Full Text] [Related]
13. Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation.
Kudo Y; Kitajima S; Ogawa I; Kitagawa M; Miyauchi M; Takata T
Mol Cancer Ther; 2005 Mar; 4(3):471-6. PubMed ID: 15767556
[TBL] [Abstract][Full Text] [Related]
14. Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors.
Singh HP; Wang S; Stachelek K; Lee S; Reid MW; Thornton ME; Craft CM; Grubbs BH; Cobrinik D
Proc Natl Acad Sci U S A; 2018 Oct; 115(40):E9391-E9400. PubMed ID: 30213853
[TBL] [Abstract][Full Text] [Related]
15. Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lines.
Ling YH; Li T; Yuan Z; Haigentz M; Weber TK; Perez-Soler R
Mol Pharmacol; 2007 Aug; 72(2):248-58. PubMed ID: 17456787
[TBL] [Abstract][Full Text] [Related]
16. SKP2, positively regulated by circ_ODC1/miR-422a axis, promotes the proliferation of retinoblastoma.
Du S; Wang S; Zhang F; Lv Y
J Cell Biochem; 2020 Jan; 121(1):322-331. PubMed ID: 31297892
[TBL] [Abstract][Full Text] [Related]
17. Effects of lentivirus-mediated astrocyte elevated gene-1 overexpression on proliferation and apoptosis of human retinoblastoma cells.
Bai H; Chang Y; Li B; Mao Y; Jonas JB
Acta Ophthalmol; 2019 May; 97(3):e397-e402. PubMed ID: 30694025
[TBL] [Abstract][Full Text] [Related]
18. Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis.
Zhao H; Wang H; Bauzon F; Lu Z; Fu H; Cui J; Zhu L
J Biol Chem; 2016 May; 291(19):10201-9. PubMed ID: 26966181
[TBL] [Abstract][Full Text] [Related]
19. Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model.
Li X; Yokoyama NN; Zhang S; Ding L; Liu HM; Lilly MB; Mercola D; Zi X
Oncotarget; 2015 Dec; 6(39):41809-24. PubMed ID: 26497688
[TBL] [Abstract][Full Text] [Related]
20. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells.
Wang ST; Ho HJ; Lin JT; Shieh JJ; Wu CY
Cell Death Dis; 2017 Feb; 8(2):e2626. PubMed ID: 28230855
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]