BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 37010497)

  • 1. 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2).
    Burgio AL; Shrader CW; Kharel Y; Huang T; Salamoun JM; Lynch KR; Santos WL
    J Med Chem; 2023 Apr; 66(8):5873-5891. PubMed ID: 37010497
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors.
    Fritzemeier R; Foster D; Peralta A; Payette M; Kharel Y; Huang T; Lynch KR; Santos WL
    J Med Chem; 2022 Jun; 65(11):7656-7681. PubMed ID: 35609189
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Imidazole-based sphingosine-1-phosphate transporter Spns2 inhibitors.
    Shrader CW; Foster D; Kharel Y; Huang T; Lynch KR; Santos WL
    Bioorg Med Chem Lett; 2023 Nov; 96():129516. PubMed ID: 37832799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
    Chen H; Ahmed S; Zhao H; Elghobashi-Meinhardt N; Dai Y; Kim JH; McDonald JG; Li X; Lee CH
    Cell; 2023 Jun; 186(12):2644-2655.e16. PubMed ID: 37224812
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assay of Sphingosine 1-phosphate Transporter Spinster Homolog 2 (Spns2) Inhibitors.
    Kharel Y; Huang T; Santos WL; Lynch KR
    SLAS Discov; 2023 Sep; 28(6):284-287. PubMed ID: 37454972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of sphingosine-1-phosphate transporter Spns2 in immune system function.
    Nijnik A; Clare S; Hale C; Chen J; Raisen C; Mottram L; Lucas M; Estabel J; Ryder E; Adissu H; ; Adams NC; Ramirez-Solis R; White JK; Steel KP; Dougan G; Hancock RE
    J Immunol; 2012 Jul; 189(1):102-11. PubMed ID: 22664872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium.
    Fu P; Ebenezer DL; Berdyshev EV; Bronova IA; Shaaya M; Harijith A; Natarajan V
    J Biol Chem; 2016 Dec; 291(53):27187-27203. PubMed ID: 27864331
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice.
    Fukuhara S; Simmons S; Kawamura S; Inoue A; Orba Y; Tokudome T; Sunden Y; Arai Y; Moriwaki K; Ishida J; Uemura A; Kiyonari H; Abe T; Fukamizu A; Hirashima M; Sawa H; Aoki J; Ishii M; Mochizuki N
    J Clin Invest; 2012 Apr; 122(4):1416-26. PubMed ID: 22406534
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network.
    Nagahashi M; Kim EY; Yamada A; Ramachandran S; Allegood JC; Hait NC; Maceyka M; Milstien S; Takabe K; Spiegel S
    FASEB J; 2013 Mar; 27(3):1001-11. PubMed ID: 23180825
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions.
    Hasan Z; Nguyen TQ; Lam BWS; Wong JHX; Wong CCY; Tan CKH; Yu J; Thiam CH; Zhang Y; Angeli V; Nguyen LN
    Cell Mol Life Sci; 2022 Oct; 79(11):541. PubMed ID: 36198832
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The solute carrier SPNS2 recruits PI(4,5)P
    Tang H; Li H; Prakaash D; Pedebos C; Qiu X; Sauer DB; Khalid S; Duerr K; Robinson CV
    Mol Cell; 2023 Aug; 83(15):2739-2752.e5. PubMed ID: 37499662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New insights into functions of the sphingosine-1-phosphate transporter SPNS2.
    Spiegel S; Maczis MA; Maceyka M; Milstien S
    J Lipid Res; 2019 Mar; 60(3):484-489. PubMed ID: 30655317
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate.
    Mendoza A; Bréart B; Ramos-Perez WD; Pitt LA; Gobert M; Sunkara M; Lafaille JJ; Morris AJ; Schwab SR
    Cell Rep; 2012 Nov; 2(5):1104-10. PubMed ID: 23103166
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine-1-Phosphate.
    Del Gaudio I; Rubinelli L; Sasset L; Wadsack C; Hla T; Di Lorenzo A
    J Am Heart Assoc; 2021 Jul; 10(14):e021261. PubMed ID: 34240614
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Spinster homolog 2 in cancers, its functions and mechanisms.
    Fang L; Hou J; Cao Y; Shan JJ; Zhao J
    Cell Signal; 2021 Jan; 77():109821. PubMed ID: 33144184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
    Harijith A; Pendyala S; Ebenezer DL; Ha AW; Fu P; Wang YT; Ma K; Toth PT; Berdyshev EV; Kanteti P; Natarajan V
    Am J Physiol Lung Cell Mol Physiol; 2016 Aug; 311(2):L337-51. PubMed ID: 27343196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells.
    Hisano Y; Kobayashi N; Yamaguchi A; Nishi T
    PLoS One; 2012; 7(6):e38941. PubMed ID: 22723910
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases.
    Donoviel MS; Hait NC; Ramachandran S; Maceyka M; Takabe K; Milstien S; Oravecz T; Spiegel S
    FASEB J; 2015 Dec; 29(12):5018-28. PubMed ID: 26324848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts.
    Laurenzana A; Cencetti F; Serratì S; Bruno G; Japtok L; Bianchini F; Torre E; Fibbi G; Del Rosso M; Bruni P; Donati C
    J Mol Med (Berl); 2015 Oct; 93(10):1145-57. PubMed ID: 25952146
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells.
    Blanchard O; Stepanovska B; Starck M; Erhardt M; Römer I; Meyer Zu Heringdorf D; Pfeilschifter J; Zangemeister-Wittke U; Huwiler A
    Int J Mol Sci; 2018 May; 19(5):. PubMed ID: 29772789
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.