BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 37011906)

  • 21. Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.
    Thompson JW; Nagel J; Hoving S; Gerrits B; Bauer A; Thomas JR; Kirschner MW; Schirle M; Luchansky SJ
    J Biol Chem; 2014 Oct; 289(42):28942-55. PubMed ID: 25147182
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Covalent fragment-based ligand screening approaches for identification of novel ubiquitin proteasome system modulators.
    Rothweiler EM; Brennan PE; Huber KVM
    Biol Chem; 2022 Mar; 403(4):391-402. PubMed ID: 35191283
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.
    Akuffo AA; Alontaga AY; Metcalf R; Beatty MS; Becker A; McDaniel JM; Hesterberg RS; Goodheart WE; Gunawan S; Ayaz M; Yang Y; Karim MR; Orobello ME; Daniel K; Guida W; Yoder JA; Rajadhyaksha AM; Schönbrunn E; Lawrence HR; Lawrence NJ; Epling-Burnette PK
    J Biol Chem; 2018 Apr; 293(16):6187-6200. PubMed ID: 29449372
    [TBL] [Abstract][Full Text] [Related]  

  • 24. ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain.
    Razinia Z; Baldassarre M; Cantelli G; Calderwood DA
    J Biol Chem; 2013 Nov; 288(44):32093-105. PubMed ID: 24052262
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins.
    Bayle J; Lopez S; Iwaï K; Dubreuil P; De Sepulveda P
    FEBS Lett; 2006 May; 580(11):2609-14. PubMed ID: 16643902
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Antibody targeting of E3 ubiquitin ligases for receptor degradation.
    Marei H; Tsai WK; Kee YS; Ruiz K; He J; Cox C; Sun T; Penikalapati S; Dwivedi P; Choi M; Kan D; Saenz-Lopez P; Dorighi K; Zhang P; Kschonsak YT; Kljavin N; Amin D; Kim I; Mancini AG; Nguyen T; Wang C; Janezic E; Doan A; Mai E; Xi H; Gu C; Heinlein M; Biehs B; Wu J; Lehoux I; Harris S; Comps-Agrar L; Seshasayee D; de Sauvage FJ; Grimmer M; Li J; Agard NJ; de Sousa E Melo F
    Nature; 2022 Oct; 610(7930):182-189. PubMed ID: 36131013
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase.
    Kong KE; Fischer B; Meurer M; Kats I; Li Z; Rühle F; Barry JD; Kirrmaier D; Chevyreva V; San Luis BJ; Costanzo M; Huber W; Andrews BJ; Boone C; Knop M; Khmelinskii A
    Mol Cell; 2021 Jun; 81(11):2460-2476.e11. PubMed ID: 33974913
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.
    Xie Y; Avello M; Schirle M; McWhinnie E; Feng Y; Bric-Furlong E; Wilson C; Nathans R; Zhang J; Kirschner MW; Huang SM; Cong F
    J Biol Chem; 2013 Feb; 288(5):2976-85. PubMed ID: 23184937
    [TBL] [Abstract][Full Text] [Related]  

  • 29. From
    Cabana VC; Lussier MP
    Cells; 2022 Jan; 11(3):. PubMed ID: 35159190
    [TBL] [Abstract][Full Text] [Related]  

  • 30. CRL4B E3 ligase recruited by PRPF19 inhibits SARS-CoV-2 infection by targeting ORF6 for ubiquitin-dependent degradation.
    Zhang L; Hao P; Chen X; Lv S; Gao W; Li C; Li Z; Zhang W
    mBio; 2024 Feb; 15(2):e0307123. PubMed ID: 38265236
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The role of E3 ubiquitin ligase in multiple myeloma: potential for cereblon E3 ligase modulators in the treatment of relapsed/refractory disease.
    Richardson PG; Mateos MV; Vangsted AJ; Ramasamy K; Abildgaard N; Ho PJ; Quach H; Bahlis NJ
    Expert Rev Proteomics; 2022; 19(4-6):235-246. PubMed ID: 36342226
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Discovery of E3 Ligase Ligands for Target Protein Degradation.
    Lee J; Lee Y; Jung YM; Park JH; Yoo HS; Park J
    Molecules; 2022 Oct; 27(19):. PubMed ID: 36235052
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.
    Poirson J; Biquand E; Straub ML; Cassonnet P; Nominé Y; Jones L; van der Werf S; Travé G; Zanier K; Jacob Y; Demeret C; Masson M
    FEBS J; 2017 Oct; 284(19):3171-3201. PubMed ID: 28786561
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications.
    Henning NJ; Manford AG; Spradlin JN; Brittain SM; Zhang E; McKenna JM; Tallarico JA; Schirle M; Rape M; Nomura DK
    J Am Chem Soc; 2022 Jan; 144(2):701-708. PubMed ID: 34994556
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Harnessing nanobodies for target protein degradation through the Affinity-directed PROtein Missile (AdPROM) system.
    Carton B; Röth S; Macartney TJ; Sapkota GP
    Methods Enzymol; 2023; 681():61-79. PubMed ID: 36764764
    [TBL] [Abstract][Full Text] [Related]  

  • 36. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
    Lochab S; Pal P; Kapoor I; Kanaujiya JK; Sanyal S; Behre G; Trivedi AK
    Biochim Biophys Acta; 2013 Dec; 1833(12):2639-2652. PubMed ID: 23820376
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Current Challenges in Small Molecule Proximity-Inducing Compound Development for Targeted Protein Degradation Using the Ubiquitin Proteasomal System.
    Radhakrishnan S; Hoff O; Muellner MK
    Molecules; 2022 Nov; 27(23):. PubMed ID: 36500212
    [TBL] [Abstract][Full Text] [Related]  

  • 38. ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation.
    Sun R; Meng Z; Lee H; Offringa R; Niehrs C
    Cell Chem Biol; 2023 Jul; 30(7):739-752.e8. PubMed ID: 37321224
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain.
    Ho SR; Lee YJ; Lin WC
    J Biol Chem; 2015 Sep; 290(38):23026-38. PubMed ID: 26216882
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Small molecule induced STING degradation facilitated by the HECT ligase HERC4.
    Mutlu M; Schmidt I; Morrison AI; Goretzki B; Freuler F; Begue D; Simic O; Pythoud N; Ahrne E; Kapps S; Roest S; Bonenfant D; Jeanpierre D; Tran TT; Maher R; An S; Rietsch A; Nigsch F; Hofmann A; Reece-Hoyes J; Parker CN; Guerini D
    Nat Commun; 2024 May; 15(1):4584. PubMed ID: 38811577
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.