BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 37017344)

  • 1. GDNF family receptor alpha-like antagonist antibody alleviates chemotherapy-induced cachexia in melanoma-bearing mice.
    Lee BY; Jeong J; Jung I; Cho H; Jung D; Shin J; Park JK; Park E; Noh S; Shin S; Kang S; Heo JI; Baek MC; Yea K
    J Cachexia Sarcopenia Muscle; 2023 Jun; 14(3):1441-1453. PubMed ID: 37017344
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.
    Suriben R; Chen M; Higbee J; Oeffinger J; Ventura R; Li B; Mondal K; Gao Z; Ayupova D; Taskar P; Li D; Starck SR; Chen HH; McEntee M; Katewa SD; Phung V; Wang M; Kekatpure A; Lakshminarasimhan D; White A; Olland A; Haldankar R; Solloway MJ; Hsu JY; Wang Y; Tang J; Lindhout DA; Allan BB
    Nat Med; 2020 Aug; 26(8):1264-1270. PubMed ID: 32661391
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS.
    Tsai VW; Zhang HP; Manandhar R; Schofield P; Christ D; Lee-Ng KKM; Lebhar H; Marquis CP; Husaini Y; Brown DA; Breit SN
    Int J Obes (Lond); 2019 Dec; 43(12):2370-2380. PubMed ID: 31152154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The GDF15-GFRAL axis mediates chemotherapy-induced fatigue in mice.
    Chelette B; Chidomere CL; Dantzer R
    Brain Behav Immun; 2023 Feb; 108():45-54. PubMed ID: 36427806
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases.
    Tsai VWW; Husaini Y; Sainsbury A; Brown DA; Breit SN
    Cell Metab; 2018 Sep; 28(3):353-368. PubMed ID: 30184485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
    Emmerson PJ; Wang F; Du Y; Liu Q; Pickard RT; Gonciarz MD; Coskun T; Hamang MJ; Sindelar DK; Ballman KK; Foltz LA; Muppidi A; Alsina-Fernandez J; Barnard GC; Tang JX; Liu X; Mao X; Siegel R; Sloan JH; Mitchell PJ; Zhang BB; Gimeno RE; Shan B; Wu X
    Nat Med; 2017 Oct; 23(10):1215-1219. PubMed ID: 28846098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling.
    Worth AA; Shoop R; Tye K; Feetham CH; D'Agostino G; Dodd GT; Reimann F; Gribble FM; Beebe EC; Dunbar JD; Alexander-Chacko JT; Sindelar DK; Coskun T; Emmerson PJ; Luckman SM
    Elife; 2020 Jul; 9():. PubMed ID: 32723474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
    Breit SN; Brown DA; Tsai VW
    Annu Rev Physiol; 2021 Feb; 83():127-151. PubMed ID: 33228454
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced Malaise.
    Borner T; Tinsley IC; Milliken BT; Doebley SA; Najjar NR; Kerwood DJ; De Jonghe BC; Hayes MR; Doyle RP
    J Med Chem; 2023 Aug; 66(16):11237-11249. PubMed ID: 37506293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting Obesity and Cachexia: Identification of the GFRAL Receptor-MIC-1/GDF15 Pathway.
    Breit SN; Tsai VW; Brown DA
    Trends Mol Med; 2017 Dec; 23(12):1065-1067. PubMed ID: 29129392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice.
    Frikke-Schmidt H; Hultman K; Galaske JW; Jørgensen SB; Myers MG; Seeley RJ
    Mol Metab; 2019 Mar; 21():13-21. PubMed ID: 30685336
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling.
    Alexopoulou F; Buch-Månson N; Pedersen SL; Vrang N; Fink LN; Strømgaard K
    Peptides; 2023 Oct; 168():171063. PubMed ID: 37495041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GDF15: A Hormone Conveying Somatic Distress to the Brain.
    Lockhart SM; Saudek V; O'Rahilly S
    Endocr Rev; 2020 Aug; 41(4):. PubMed ID: 32310257
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
    Mullican SE; Lin-Schmidt X; Chin CN; Chavez JA; Furman JL; Armstrong AA; Beck SC; South VJ; Dinh TQ; Cash-Mason TD; Cavanaugh CR; Nelson S; Huang C; Hunter MJ; Rangwala SM
    Nat Med; 2017 Oct; 23(10):1150-1157. PubMed ID: 28846097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Body weight regulation via MT1-MMP-mediated cleavage of GFRAL.
    Chow CFW; Guo X; Asthana P; Zhang S; Wong SKK; Fallah S; Che S; Gurung S; Wang Z; Lee KB; Ge X; Yuan S; Xu H; Ip JPK; Jiang Z; Zhai L; Wu J; Zhang Y; Mahato AK; Saarma M; Lin CY; Kwan HY; Huang T; Lyu A; Zhou Z; Bian ZX; Wong HLX
    Nat Metab; 2022 Feb; 4(2):203-212. PubMed ID: 35177851
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond.
    Mullican SE; Rangwala SM
    Trends Endocrinol Metab; 2018 Aug; 29(8):560-570. PubMed ID: 29866502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer.
    Ahmed DS; Isnard S; Lin J; Routy B; Routy JP
    J Cancer; 2021; 12(4):1125-1132. PubMed ID: 33442410
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GFRAL Is Widely Distributed in the Brain and Peripheral Tissues of Mice.
    Fichtner K; Kalwa H; Lin MM; Gong Y; Müglitz A; Kluge M; Krügel U
    Nutrients; 2024 Mar; 16(5):. PubMed ID: 38474863
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
    Hsu JY; Crawley S; Chen M; Ayupova DA; Lindhout DA; Higbee J; Kutach A; Joo W; Gao Z; Fu D; To C; Mondal K; Li B; Kekatpure A; Wang M; Laird T; Horner G; Chan J; McEntee M; Lopez M; Lakshminarasimhan D; White A; Wang SP; Yao J; Yie J; Matern H; Solloway M; Haldankar R; Parsons T; Tang J; Shen WD; Alice Chen Y; Tian H; Allan BB
    Nature; 2017 Oct; 550(7675):255-259. PubMed ID: 28953886
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anorexia-cachexia syndrome in hepatoma tumour-bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC-1/GDF15.
    Borner T; Arnold M; Ruud J; Breit SN; Langhans W; Lutz TA; Blomqvist A; Riediger T
    J Cachexia Sarcopenia Muscle; 2017 Jun; 8(3):417-427. PubMed ID: 28025863
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.