BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 37029430)

  • 21. TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.
    Hellwig M; Lauffer MC; Bockmayr M; Spohn M; Merk DJ; Harrison L; Ahlfeld J; Kitowski A; Neumann JE; Ohli J; Holdhof D; Niesen J; Schoof M; Kool M; Kraus C; Zweier C; Holmberg D; Schüller U
    Acta Neuropathol; 2019 Apr; 137(4):657-673. PubMed ID: 30830316
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum.
    Heil C
    Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Lipidome signatures of metastasis in a transgenic mouse model of sonic hedgehog medulloblastoma.
    Huang D; Liu J; Eldridge RC; Gaul DA; Paine MRL; Uppal K; MacDonald TJ; Fernández FM
    Anal Bioanal Chem; 2020 Oct; 412(25):7017-7027. PubMed ID: 32794007
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma.
    Pak E; MacKenzie EL; Zhao X; Pazyra-Murphy MF; Park PMC; Wu L; Shaw DL; Addleson EC; Cayer SS; Lopez BG; Agar NYR; Rubin LL; Qi J; Merk DJ; Segal RA
    Neuro Oncol; 2019 Sep; 21(9):1150-1163. PubMed ID: 31111916
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
    Faria CC; Golbourn BJ; Dubuc AM; Remke M; Diaz RJ; Agnihotri S; Luck A; Sabha N; Olsen S; Wu X; Garzia L; Ramaswamy V; Mack SC; Wang X; Leadley M; Reynaud D; Ermini L; Post M; Northcott PA; Pfister SM; Croul SE; Kool M; Korshunov A; Smith CA; Taylor MD; Rutka JT
    Cancer Res; 2015 Jan; 75(1):134-46. PubMed ID: 25391241
    [TBL] [Abstract][Full Text] [Related]  

  • 26. CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model.
    Tan IL; Arifa RDN; Rallapalli H; Kana V; Lao Z; Sanghrajka RM; Sumru Bayin N; Tanne A; Wojcinski A; Korshunov A; Bhardwaj N; Merad M; Turnbull DH; Lafaille JJ; Joyner AL
    Oncogene; 2021 Jan; 40(2):396-407. PubMed ID: 33159168
    [TBL] [Abstract][Full Text] [Related]  

  • 27. ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.
    Grausam KB; Dooyema SDR; Bihannic L; Premathilake H; Morrissy AS; Forget A; Schaefer AM; Gundelach JH; Macura S; Maher DM; Wang X; Heglin AH; Ge X; Zeng E; Puget S; Chandrasekar I; Surendran K; Bram RJ; Schüller U; Talyor MD; Ayrault O; Zhao H
    Cancer Res; 2017 Jul; 77(14):3766-3777. PubMed ID: 28490517
    [TBL] [Abstract][Full Text] [Related]  

  • 28. An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.
    Wijaya J; Vo BT; Liu J; Xu B; Wu G; Wang Y; Peng J; Zhang J; Janke LJ; Orr BA; Yu J; Roussel MF; Schuetz JD
    Cancer Res; 2020 Apr; 80(7):1524-1537. PubMed ID: 31948942
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration.
    Callegari K; Maegawa S; Bravo-Alegria J; Gopalakrishnan V
    Cell Commun Signal; 2018 Sep; 16(1):60. PubMed ID: 30227871
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression.
    Zagozewski J; Borlase S; Guppy BJ; Coudière-Morrison L; Shahriary GM; Gordon V; Liang L; Cheng S; Porter CJ; Kelley R; Hawkins C; Chan JA; Liang Y; Gong J; Nör C; Saulnier O; Wechsler-Reya RJ; Ramaswamy V; Werbowetski-Ogilvie TE
    Commun Biol; 2022 Jul; 5(1):697. PubMed ID: 35835937
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.
    Al-Halabi H; Nantel A; Klekner A; Guiot MC; Albrecht S; Hauser P; Garami M; Bognar L; Kavan P; Gerges N; Shirinian M; Roberge D; Muanza T; Jabado N
    Acta Neuropathol; 2011 Feb; 121(2):229-39. PubMed ID: 21107850
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.
    Bhatia B; Hsieh M; Kenney AM; Nahlé Z
    Oncogene; 2011 Jan; 30(4):410-22. PubMed ID: 20890301
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
    Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD
    Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Low Expression of the
    de Araújo MA; Malafaia O; Ribas Filho JM; Fratini L; Roesler R; Isolan GR
    Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511358
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix.
    Cheng Y; Franco-Barraza J; Wang Y; Zheng C; Zhang L; Qu Y; Long Y; Cukierman E; Yang ZJ
    Lab Invest; 2020 Sep; 100(9):1208-1222. PubMed ID: 32457352
    [TBL] [Abstract][Full Text] [Related]  

  • 36. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.
    Fernandez-L A; Northcott PA; Dalton J; Fraga C; Ellison D; Angers S; Taylor MD; Kenney AM
    Genes Dev; 2009 Dec; 23(23):2729-41. PubMed ID: 19952108
    [TBL] [Abstract][Full Text] [Related]  

  • 37. RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling.
    Ma P; An T; Zhu L; Zhang L; Wang H; Ren B; Sun B; Zhou X; Li Y; Mao B
    Development; 2020 Jun; 147(21):. PubMed ID: 32376680
    [TBL] [Abstract][Full Text] [Related]  

  • 38. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
    Zinke J; Schneider FT; Harter PN; Thom S; Ziegler N; Toftgård R; Plate KH; Liebner S
    Mol Cancer; 2015 Feb; 14(1):17. PubMed ID: 25645196
    [TBL] [Abstract][Full Text] [Related]  

  • 39. FANCD2 deficiency sensitizes SHH medulloblastoma to radiotherapy via ferroptosis.
    Zhou H; Wang YX; Wu M; Lan X; Xiang D; Cai R; Ma Q; Miao J; Fang X; Wang J; Luo D; He Z; Cui Y; Liang P; Wang Y; Bian XW
    J Pathol; 2024 Apr; 262(4):427-440. PubMed ID: 38229567
    [TBL] [Abstract][Full Text] [Related]  

  • 40. WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.
    Doucette TA; Yang Y; Pedone C; Kim JY; Dubuc A; Northcott PD; Taylor MD; Fults DW; Rao G
    Neurosurgery; 2012 Apr; 70(4):1003-10; discussion 1010. PubMed ID: 22037313
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.