BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 37035245)

  • 1. Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells.
    Sbirkov Y; Schenk T; Kwok C; Stengel S; Brown R; Brown G; Chesler L; Zelent A; Fuchter MJ; Petrie K
    Front Cell Dev Biol; 2023; 11():1076458. PubMed ID: 37035245
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
    Schenk T; Chen WC; Göllner S; Howell L; Jin L; Hebestreit K; Klein HU; Popescu AC; Burnett A; Mills K; Casero RA; Marton L; Woster P; Minden MD; Dugas M; Wang JC; Dick JE; Müller-Tidow C; Petrie K; Zelent A
    Nat Med; 2012 Mar; 18(4):605-11. PubMed ID: 22406747
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells.
    Liu L; Liu L; Leung LH; Cooney AJ; Chen C; Rosengart TK; Ma Y; Yang J
    J Biol Chem; 2015 Apr; 290(17):10599-609. PubMed ID: 25737450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.
    Sakamoto K; Imamura T; Yano M; Yoshida H; Fujiki A; Hirashima Y; Hosoi H
    Blood Cancer J; 2014 Apr; 4(4):e205. PubMed ID: 24769646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML.
    Kahl M; Brioli A; Bens M; Perner F; Kresinsky A; Schnetzke U; Hinze A; Sbirkov Y; Stengel S; Simonetti G; Martinelli G; Petrie K; Zelent A; Böhmer FD; Groth M; Ernst T; Heidel FH; Scholl S; Hochhaus A; Schenk T
    Leukemia; 2019 Nov; 33(11):2628-2639. PubMed ID: 31576004
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The transcriptional corepressor CBFA2T3 inhibits all-
    Steinauer N; Guo C; Zhang J
    J Biol Chem; 2020 Jul; 295(27):8887-8900. PubMed ID: 32434928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis.
    Ishiguro K; Kitajima H; Niinuma T; Maruyama R; Nishiyama N; Ohtani H; Sudo G; Toyota M; Sasaki H; Yamamoto E; Kai M; Nakase H; Suzuki H
    Cell Death Discov; 2021 Jan; 7(1):7. PubMed ID: 33436557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-
    Sunami Y; Araki M; Kan S; Ito A; Hironaka Y; Imai M; Morishita S; Ohsaka A; Komatsu N
    J Biol Chem; 2017 Feb; 292(7):2815-2829. PubMed ID: 28053092
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reprogramming acute myeloid leukemia into sensitivity for retinoic-acid-driven differentiation.
    van Gils N; Verhagen HJMP; Smit L
    Exp Hematol; 2017 Aug; 52():12-23. PubMed ID: 28456748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. All-trans retinoic acid induces differentiation in primary acute myeloid leukemia blasts carrying an inversion of chromosome 16.
    Dembitz V; Lalic H; Tomic B; Smoljo T; Batinic J; Dubravcic K; Batinic D; Bedalov A; Visnjic D
    Int J Hematol; 2022 Jan; 115(1):43-53. PubMed ID: 34546543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells.
    Fiskus W; Pranpat M; Balasis M; Herger B; Rao R; Chinnaiyan A; Atadja P; Bhalla K
    Mol Cancer Ther; 2006 Dec; 5(12):3096-104. PubMed ID: 17172412
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation.
    Rejlova K; Musilova A; Kramarzova KS; Zaliova M; Fiser K; Alberich-Jorda M; Trka J; Starkova J
    Epigenetics; 2018; 13(1):73-84. PubMed ID: 29224413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a.
    Vinson DA; Stephens KE; O'Meally RN; Bhat S; Dancy BCR; Cole RN; Yegnasubramanian S; Taverna SD
    Epigenetics Chromatin; 2022 Nov; 15(1):36. PubMed ID: 36411491
    [TBL] [Abstract][Full Text] [Related]  

  • 14. All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
    Orfali N; O'Donovan TR; Cahill MR; Benjamin D; Nanus DM; McKenna SL; Gudas LJ; Mongan NP
    Eur J Haematol; 2020 Mar; 104(3):236-250. PubMed ID: 31811682
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation.
    Rafiq S; Mungure I; Banz Y; Niklaus NJ; Kaufmann T; Müller S; Jacquel A; Robert G; Auberger P; Torbett BE; Muller S; Tschan MP; Humbert M
    Pharmacology; 2024 Apr; ():1-15. PubMed ID: 38569476
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The HER2 inhibitor TAK165 Sensitizes Human Acute Myeloid Leukemia Cells to Retinoic Acid-Induced Myeloid Differentiation by activating MEK/ERK mediated RARα/STAT1 axis.
    Shao X; Liu Y; Li Y; Xian M; Zhou Q; Yang B; Ying M; He Q
    Sci Rep; 2016 Apr; 6():24589. PubMed ID: 27074819
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
    Fiskus W; Wang Y; Sreekumar A; Buckley KM; Shi H; Jillella A; Ustun C; Rao R; Fernandez P; Chen J; Balusu R; Koul S; Atadja P; Marquez VE; Bhalla KN
    Blood; 2009 Sep; 114(13):2733-43. PubMed ID: 19638619
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells.
    Chee LC; Hendy J; Purton LE; McArthur GA
    Leukemia; 2013 Jun; 27(6):1369-80. PubMed ID: 23228968
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.
    Pappano WN; Guo J; He Y; Ferguson D; Jagadeeswaran S; Osterling DJ; Gao W; Spence JK; Pliushchev M; Sweis RF; Buchanan FG; Michaelides MR; Shoemaker AR; Tse C; Chiang GG
    PLoS One; 2015; 10(7):e0131716. PubMed ID: 26147105
    [TBL] [Abstract][Full Text] [Related]  

  • 20. S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia.
    Gianni M; Terao M; Kurosaki M; Paroni G; Brunelli L; Pastorelli R; Zanetti A; Lupi M; Acquavita A; Bolis M; Fratelli M; Rochette-Egly C; Garattini E
    Oncogene; 2019 Apr; 38(14):2482-2500. PubMed ID: 30532072
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.