BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 37037699)

  • 1. In vitro effects of combining Mim8 with factor VIII, FVIIa, and activated prothrombin complex concentrates in thrombin generation assays.
    Lund J; Jensen K; Burnier L; Ezban M
    J Thromb Haemost; 2023 Jun; 21(6):1493-1502. PubMed ID: 37037699
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of a next generation factor VIII mimetic bispecific antibody (Mim8) on assays of factor VIII activity and thrombin generation.
    Bowyer AE; Kitchen S; Ezban M
    J Thromb Haemost; 2023 Mar; 21(3):480-487. PubMed ID: 36696203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel therapeutic approach combining human plasma-derived Factors VIIa and X for haemophiliacs with inhibitors: evidence of a higher thrombin generation rate in vitro and more sustained haemostatic activity in vivo than obtained with Factor VIIa alone.
    Tomokiyo K; Nakatomi Y; Araki T; Teshima K; Nakano H; Nakagaki T; Miyamoto S; Funatsu A; Iwanaga S
    Vox Sang; 2003 Nov; 85(4):290-9. PubMed ID: 14633255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thrombin generation potential in the presence of concizumab and rFVIIa, APCC, rFVIII, or rFIX: In vitro and ex vivo analyses.
    Kjalke M; Kjelgaard-Hansen M; Andersen S; Hilden I
    J Thromb Haemost; 2021 Jul; 19(7):1687-1696. PubMed ID: 33819375
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potential role of recombinant factor VIIa as a hemostatic agent.
    Hedner U; Erhardtsen E
    Clin Adv Hematol Oncol; 2003 Feb; 1(2):112-9. PubMed ID: 16224390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.
    Lauritzen B; Bjelke M; Björkdahl O; Bloem E; Keane K; Kjalke M; Rossen M; Lippert SL; Weldingh KN; Skydsgaard M; Kjellev S
    J Thromb Haemost; 2022 Jun; 20(6):1312-1324. PubMed ID: 35191180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. History of rFVIIa therapy.
    Hedner U
    Thromb Res; 2010 Apr; 125 Suppl 1():S4-6. PubMed ID: 20188400
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FRONTIER1: a partially randomized phase 2 study assessing the safety, pharmacokinetics, and pharmacodynamics of Mim8, a factor VIIIa mimetic.
    Lentz SR; Chowdary P; Gil L; Lopez-Jaime FJ; Mahlangu J; Matytsina I; Nielsen AL; Windyga J
    J Thromb Haemost; 2024 Apr; 22(4):990-1000. PubMed ID: 38142846
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thrombin generation on vascular cells in the presence of factor VIII and/or emicizumab.
    Atsou S; Schellenberg C; Lagrange J; Lacolley P; Lenting PJ; Denis CV; Christophe OD; Regnault V
    J Thromb Haemost; 2024 Jan; 22(1):112-125. PubMed ID: 37776978
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hemophilia and von Willebrand's disease: 2. Management. Association of Hemophilia Clinic Directors of Canada.
    CMAJ; 1995 Jul; 153(2):147-57. PubMed ID: 7600466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Safety, pharmacokinetics and efficacy of factor VIIa formulated with PEGylated liposomes in haemophilia A patients with inhibitors to factor VIII--an open label, exploratory, cross-over, phase I/II study.
    Spira J; Plyushch O; Zozulya N; Yatuv R; Dayan I; Bleicher A; Robinson M; Baru M
    Haemophilia; 2010 Nov; 16(6):910-8. PubMed ID: 20491957
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
    Østergaard H; Lund J; Greisen PJ; Kjellev S; Henriksen A; Lorenzen N; Johansson E; Røder G; Rasch MG; Johnsen LB; Egebjerg T; Lund S; Rahbek-Nielsen H; Gandhi PS; Lamberth K; Loftager M; Andersen LM; Bonde AC; Stavenuiter F; Madsen DE; Li X; Holm TL; Ley CD; Thygesen P; Zhu H; Zhou R; Thorn K; Yang Z; Hermit MB; Bjelke JR; Hansen BG; Hilden I
    Blood; 2021 Oct; 138(14):1258-1268. PubMed ID: 34077951
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Administration of recombinant FVIIa (rFVIIa) to concizumab-dosed monkeys is safe, and concizumab does not affect the potency of rFVIIa in hemophilic rabbits.
    Lauritzen B; Olling J; Abel KL; Augustsson C; Balling K; Bjelke M; Hegelund AC; Hilden I
    J Thromb Haemost; 2019 Mar; 17(3):460-469. PubMed ID: 30614620
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thrombin generation for monitoring hemostatic therapy in hemophilia A: A narrative review.
    Verhagen MJA; Valke LLFG; Schols SEM
    J Thromb Haemost; 2022 Apr; 20(4):794-805. PubMed ID: 35034413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tissue factor and factor VIIa as therapeutic targets in disorders of hemostasis.
    Hedner U; Ezban M
    Annu Rev Med; 2008; 59():29-41. PubMed ID: 17845136
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro evidence of a tissue factor-independent mode of action of recombinant factor VIIa in hemophilia.
    Augustsson C; Persson E
    Blood; 2014 Nov; 124(20):3172-4. PubMed ID: 25232061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A next generation FVIII mimetic bispecific antibody, Mim8, the impact on non-factor VIII related haemostasis assays.
    Bowyer AE; Hickey K; Kitchen S; Ezban M
    Haemophilia; 2023 Nov; 29(6):1633-1637. PubMed ID: 37824563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. General haemostatic agents--fact or fiction?
    Hedner U
    Pathophysiol Haemost Thromb; 2002; 32 Suppl 1():33-6. PubMed ID: 12214145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue factor pathway inhibitor in activated prothrombin complex concentrates (aPCC) moderates the effectiveness of therapy in some severe hemophilia A patients with inhibitor.
    Ogiwara K; Nogami K; Matsumoto T; Shima M
    Int J Hematol; 2014; 99(5):577-87. PubMed ID: 24687919
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A modified thrombin generation assay to evaluate the plasma coagulation potential in the presence of emicizumab, the bispecific antibody to factors IXa/X.
    Ogiwara K; Nogami K; Matsumoto N; Noguchi-Sasaki M; Hirata M; Soeda T; Shima M
    Int J Hematol; 2020 Nov; 112(5):621-630. PubMed ID: 32748217
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.