BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 37038975)

  • 1. Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists.
    Zhang D; Liu Y; Zaidi SA; Xu L; Zhan Y; Chen A; Guo J; Huang XP; Roth BL; Katritch V; Cherezov V; Zhang H
    EMBO J; 2023 Jun; 42(11):e112940. PubMed ID: 37038975
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.
    Cabana J; Holleran B; Leduc R; Escher E; Guillemette G; Lavigne P
    J Biol Chem; 2015 Jun; 290(25):15835-15854. PubMed ID: 25934394
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.
    Tang W; Strachan RT; Lefkowitz RJ; Rockman HA
    J Biol Chem; 2014 Oct; 289(41):28271-83. PubMed ID: 25170081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.
    Galandrin S; Denis C; Boularan C; Marie J; M'Kadmi C; Pilette C; Dubroca C; Nicaise Y; Seguelas MH; N'Guyen D; Banères JL; Pathak A; Sénard JM; Galés C
    Hypertension; 2016 Dec; 68(6):1365-1374. PubMed ID: 27698068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cardiovascular angiotensin II type 1 receptor biased signaling: Focus on non-Gq-, non-βarrestin-dependent signaling.
    Lymperopoulos A; Borges JI; Carbone AM; Cora N; Sizova A
    Pharmacol Res; 2021 Dec; 174():105943. PubMed ID: 34662735
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
    Wilson PC; Lee MH; Appleton KM; El-Shewy HM; Morinelli TA; Peterson YK; Luttrell LM; Jaffa AA
    J Biol Chem; 2013 Jun; 288(26):18872-84. PubMed ID: 23661707
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adrenal angiotensin II type 1 receptor biased signaling: The case for "biased" inverse agonism for effective aldosterone suppression.
    Ferraino KE; Cora N; Pollard CM; Sizova A; Maning J; Lymperopoulos A
    Cell Signal; 2021 Jun; 82():109967. PubMed ID: 33640432
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of biased signaling at a G protein-coupled receptor in overexpressed systems.
    Li A; Liu S; Huang R; Ahn S; Lefkowitz RJ
    PLoS One; 2023; 18(3):e0283477. PubMed ID: 36961836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Angiotensin II cyclic analogs as tools to investigate AT
    St-Pierre D; Cabana J; Holleran BJ; Besserer-Offroy É; Escher E; Guillemette G; Lavigne P; Leduc R
    Biochem Pharmacol; 2018 Aug; 154():104-117. PubMed ID: 29684376
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biased agonists differentially modulate the receptor conformation ensembles in Angiotensin II type 1 receptor.
    Nivedha AK; Lee S; Vaidehi N
    J Mol Graph Model; 2023 Jan; 118():108365. PubMed ID: 36335829
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
    Wingler LM; Skiba MA; McMahon C; Staus DP; Kleinhenz ALW; Suomivuori CM; Latorraca NR; Dror RO; Lefkowitz RJ; Kruse AC
    Science; 2020 Feb; 367(6480):888-892. PubMed ID: 32079768
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of the fate of type I angiotensin receptor after biased activation.
    Szakadáti G; Tóth AD; Oláh I; Erdélyi LS; Balla T; Várnai P; Hunyady L; Balla A
    Mol Pharmacol; 2015 Jun; 87(6):972-81. PubMed ID: 25804845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative evaluation of biased agonists Sarcosine
    Noto NM; Restrepo YM; Pang HW; Stoyell-Conti F; West CA; Speth RC
    Pharmacol Res Perspect; 2023 Feb; 11(1):e01053. PubMed ID: 36639940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT
    Teixeira LB; Parreiras-E-Silva LT; Bruder-Nascimento T; Duarte DA; Simões SC; Costa RM; Rodríguez DY; Ferreira PAB; Silva CAA; Abrao EP; Oliveira EB; Bouvier M; Tostes RC; Costa-Neto CM
    Sci Rep; 2017 Sep; 7(1):11903. PubMed ID: 28928410
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes.
    Delaitre C; Boisbrun M; Lecat S; Dupuis F
    Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34201646
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity.
    Domazet I; Holleran BJ; Richard A; Vandenberghe C; Lavigne P; Escher E; Leduc R; Guillemette G
    Mol Pharmacol; 2015 Jun; 87(6):982-95. PubMed ID: 25808928
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel high molecular weight albumin-conjugated angiotensin II activates β-arrestin and G-protein pathways.
    Pang HW; Linares A; Couling L; Santollo J; Ancheta L; Daniels D; Speth RC
    Endocrine; 2019 Nov; 66(2):349-359. PubMed ID: 31020463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis.
    Kendall RT; Lee MH; Pleasant DL; Robinson K; Kuppuswamy D; McDermott PJ; Luttrell LM
    J Biol Chem; 2014 Sep; 289(38):26155-26166. PubMed ID: 25081544
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ezrin, radixin, and moesin phosphorylation in NIH3T3 cells revealed angiotensin II type 1 receptor cell-type-dependent biased signaling.
    Ibrahim IA; Nakaya M; Kurose H
    J Pharmacol Sci; 2013; 122(1):1-9. PubMed ID: 23575451
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Angiotensin (1-7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptor.
    Gaidarov I; Adams J; Frazer J; Anthony T; Chen X; Gatlin J; Semple G; Unett DJ
    Cell Signal; 2018 Oct; 50():9-24. PubMed ID: 29928987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.