213 related articles for article (PubMed ID: 37039381)
1. Notch signaling inactivation by small molecule γ-secretase inhibitors restores the multiciliated cell population in the airway epithelium.
Vladar EK; Kunimoto K; Rojas-Hernandez LS; Spano JM; Sellers ZM; Joo NS; Cooney RA; Axelrod JD; Milla CE
Am J Physiol Lung Cell Mol Physiol; 2023 Jun; 324(6):L771-L782. PubMed ID: 37039381
[TBL] [Abstract][Full Text] [Related]
2. Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells.
Kazanjian A; Noah T; Brown D; Burkart J; Shroyer NF
Gastroenterology; 2010 Sep; 139(3):918-28, 928.e1-6. PubMed ID: 20621629
[TBL] [Abstract][Full Text] [Related]
3. Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells.
Firth AL; Dargitz CT; Qualls SJ; Menon T; Wright R; Singer O; Gage FH; Khanna A; Verma IM
Proc Natl Acad Sci U S A; 2014 Apr; 111(17):E1723-30. PubMed ID: 24706852
[TBL] [Abstract][Full Text] [Related]
4. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
[TBL] [Abstract][Full Text] [Related]
5. Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros.
Liu Y; Pathak N; Kramer-Zucker A; Drummond IA
Development; 2007 Mar; 134(6):1111-22. PubMed ID: 17287248
[TBL] [Abstract][Full Text] [Related]
6. More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment.
López-Nieva P; González-Sánchez L; Cobos-Fernández MÁ; Córdoba R; Santos J; Fernández-Piqueras J
Oncologist; 2021 Feb; 26(2):e298-e305. PubMed ID: 33191568
[TBL] [Abstract][Full Text] [Related]
7. Molecular and Functional Characteristics of Airway Epithelium under Chronic Hypoxia.
Wong SL; Kardia E; Vijayan A; Umashankar B; Pandzic E; Zhong L; Jaffe A; Waters SA
Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047450
[TBL] [Abstract][Full Text] [Related]
8. Blocking Notch3 Signaling Abolishes MUC5AC Production in Airway Epithelial Cells from Individuals with Asthma.
Reid AT; Nichol KS; Chander Veerati P; Moheimani F; Kicic A; Stick SM; Bartlett NW; Grainge CL; Wark PAB; Hansbro PM; Knight DA
Am J Respir Cell Mol Biol; 2020 Apr; 62(4):513-523. PubMed ID: 31922915
[TBL] [Abstract][Full Text] [Related]
9. Gamma-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses.
Kang JH; Kim BS; Uhm TG; Lee SH; Lee GR; Park CS; Chung IY
Am J Respir Crit Care Med; 2009 May; 179(10):875-82. PubMed ID: 19234107
[TBL] [Abstract][Full Text] [Related]
10. Blockade of Notch Signalling by γ-Secretase Inhibitor in Lung T Cells of Asthmatic Mice Affects T Cell Differentiation and Pulmonary Inflammation.
Zhou M; Cui ZL; Guo XJ; Ren LP; Yang M; Fan ZW; Han RC; Xu WG
Inflammation; 2015; 38(3):1281-8. PubMed ID: 25586485
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological properties of a novel and potent γ-secretase modulator as a therapeutic option for the treatment of Alzheimer's disease.
Murakami K; Watanabe T; Koike T; Kamata M; Igari T; Kondo S
Brain Res; 2016 Feb; 1633():73-86. PubMed ID: 26707977
[TBL] [Abstract][Full Text] [Related]
12. In vivo manifestation of Notch related phenotypes in zebrafish treated with Alzheimer's amyloid reducing gamma-secretase inhibitors.
Yang T; Arslanova D; Xu X; Li YM; Xia W
J Neurochem; 2010 Jun; 113(5):1200-9. PubMed ID: 20345767
[TBL] [Abstract][Full Text] [Related]
13. Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
Yang T; Arslanova D; Gu Y; Augelli-Szafran C; Xia W
Mol Brain; 2008 Nov; 1():15. PubMed ID: 18983676
[TBL] [Abstract][Full Text] [Related]
14. Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells.
Berical A; Beermann ML; Suzuki S; LeSuer J; Matte T; Davis B; Kotton D; Hawkins F
J Vis Exp; 2022 Jun; (184):. PubMed ID: 35781291
[TBL] [Abstract][Full Text] [Related]
15. NOTCH inhibition promotes bronchial stem cell renewal and epithelial barrier integrity after irradiation.
Giuranno L; Roig EM; Wansleeben C; van den Berg A; Groot AJ; Dubois L; Vooijs M
Stem Cells Transl Med; 2020 Jul; 9(7):799-812. PubMed ID: 32297712
[TBL] [Abstract][Full Text] [Related]
16. Notch signaling controls the balance of ciliated and secretory cell fates in developing airways.
Tsao PN; Vasconcelos M; Izvolsky KI; Qian J; Lu J; Cardoso WV
Development; 2009 Jul; 136(13):2297-307. PubMed ID: 19502490
[TBL] [Abstract][Full Text] [Related]
17. Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation.
Wang C; Shen J; Yukata K; Inzana JA; O'Keefe RJ; Awad HA; Hilton MJ
Bone; 2015 Apr; 73():77-89. PubMed ID: 25527421
[TBL] [Abstract][Full Text] [Related]
18. Inhibiting the Notch signaling pathway suppresses Th17-associated airway hyperresponsiveness in obese asthmatic mice.
Zeng Z; Wang L; Ma W; Zheng R; Zhang H; Zeng X; Zhang H; Zhang W
Lab Invest; 2019 Dec; 99(12):1784-1794. PubMed ID: 31409887
[TBL] [Abstract][Full Text] [Related]
19. BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cells.
Jämsä A; Belda O; Edlund M; Lindström E
J Biomed Sci; 2011 Oct; 18(1):76. PubMed ID: 22018341
[TBL] [Abstract][Full Text] [Related]
20. γ-Secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets.
Dorneburg C; Goß AV; Fischer M; Roels F; Barth TF; Berthold F; Kappler R; Oswald F; Siveke JT; Molenaar JJ; Debatin KM; Beltinger C
Oncotarget; 2016 Sep; 7(39):62799-62813. PubMed ID: 27588497
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
