BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 37040764)

  • 1. Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
    Hou X; Zhang X; Zou H; Guan M; Fu C; Wang W; Zhang ZR; Geng Y; Chen Y
    Neuron; 2023 Jun; 111(12):1898-1913.e5. PubMed ID: 37040764
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
    Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
    J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex.
    Sun Y; Islam S; Gao Y; Nakamura T; Zou K; Michikawa M
    J Neurochem; 2023 Mar; 164(6):858-874. PubMed ID: 36582176
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
    Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
    J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer's Disease.
    Nakamura T; Kawarabayashi T; Ueda T; Shimomura S; Hoshino M; Itoh K; Ihara K; Nakaji S; Takatama M; Ikeda Y; Shoji M
    J Alzheimers Dis; 2023; 93(1):333-348. PubMed ID: 36970894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
    Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
    Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
    Aleshkov S; Abraham CR; Zannis VI
    Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.
    Williams T; Bathe T; Vo Q; Sacilotto P; McFarland K; Ruiz AJ; Hery GP; Sullivan P; Borchelt DR; Prokop S; Chakrabarty P
    Acta Neuropathol Commun; 2023 Jun; 11(1):99. PubMed ID: 37337279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention.
    Keeney JT; Ibrahimi S; Zhao L
    J Alzheimers Dis; 2015; 48(2):411-24. PubMed ID: 26402005
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apolipoprotein E genotype and alpha-tocopherol modulate amyloid precursor protein metabolism and cell cycle regulation.
    Huebbe P; Schaffer S; Jofre-Monseny L; Boesch-Saadatmandi C; Minihane AM; Müller WE; Eckert GP; Rimbach G
    Mol Nutr Food Res; 2007 Dec; 51(12):1510-7. PubMed ID: 18030662
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
    Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
    J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of APOE genotype on prion-type propagation of tauopathy.
    Williams T; Ruiz AJ; Ruiz AM; Vo Q; Tsering W; Xu G; McFarland K; Giasson BI; Sullivan P; Borchelt DR; Chakrabarty P
    Acta Neuropathol Commun; 2022 Apr; 10(1):57. PubMed ID: 35440098
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma.
    Yang DS; Smith JD; Zhou Z; Gandy SE; Martins RN
    J Neurochem; 1997 Feb; 68(2):721-5. PubMed ID: 9003062
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
    Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
    Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
    Honda K; Saito Y; Saito H; Toyoda M; Abe R; Saito T; Saido TC; Michikawa M; Taru H; Sobu Y; Hata S; Nakaya T; Suzuki T
    Neurobiol Aging; 2023 Mar; 123():63-74. PubMed ID: 36638682
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer's disease patients and controls.
    Martínez-Morillo E; Hansson O; Atagi Y; Bu G; Minthon L; Diamandis EP; Nielsen HM
    Acta Neuropathol; 2014 May; 127(5):633-43. PubMed ID: 24633805
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Butterfield DA; Mattson MP
    Neurobiol Dis; 2020 May; 138():104795. PubMed ID: 32036033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.
    Baum L; Chen L; Ng HK; Pang CP
    Microsc Res Tech; 2000 Aug; 50(4):278-81. PubMed ID: 10936880
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis.
    Adaku N; Ostendorf BN; Mei W; Tavazoie SF
    Cancer Res; 2023 Sep; 83(18):3013-3025. PubMed ID: 37335131
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
    Arold S; Sullivan P; Bilousova T; Teng E; Miller CA; Poon WW; Vinters HV; Cornwell LB; Saing T; Cole GM; Gylys KH
    Acta Neuropathol; 2012 Jan; 123(1):39-52. PubMed ID: 22020632
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.