BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 37047137)

  • 21. Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders.
    Wu X; Daniels T; Molinaro C; Lilly MB; Casiano CA
    Cell Death Differ; 2002 Sep; 9(9):915-25. PubMed ID: 12181742
    [TBL] [Abstract][Full Text] [Related]  

  • 22. HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.
    Wang H; Jurado KA; Wu X; Shun MC; Li X; Ferris AL; Smith SJ; Patel PA; Fuchs JR; Cherepanov P; Kvaratskhelia M; Hughes SH; Engelman A
    Nucleic Acids Res; 2012 Dec; 40(22):11518-30. PubMed ID: 23042676
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.
    Cavalluzzo C; Christ F; Voet A; Sharma A; Singh BK; Zhang KY; Lescrinier E; De Maeyer M; Debyser Z; Van der Eycken E
    J Pept Sci; 2013 Oct; 19(10):651-8. PubMed ID: 24014475
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dynamics of the ternary complex formed by c-Myc interactor JPO2, transcriptional co-activator LEDGF/p75, and chromatin.
    Hendrix J; van Heertum B; Vanstreels E; Daelemans D; De Rijck J
    J Biol Chem; 2014 May; 289(18):12494-506. PubMed ID: 24634210
    [TBL] [Abstract][Full Text] [Related]  

  • 25. High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region.
    De Rijck J; Bartholomeeusen K; Ceulemans H; Debyser Z; Gijsbers R
    Nucleic Acids Res; 2010 Oct; 38(18):6135-47. PubMed ID: 20484370
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75.
    Mediavilla-Varela M; Pacheco FJ; Almaguel F; Perez J; Sahakian E; Daniels TR; Leoh LS; Padilla A; Wall NR; Lilly MB; De Leon M; Casiano CA
    Mol Cancer; 2009 Aug; 8():68. PubMed ID: 19715609
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding.
    Busschots K; Vercammen J; Emiliani S; Benarous R; Engelborghs Y; Christ F; Debyser Z
    J Biol Chem; 2005 May; 280(18):17841-7. PubMed ID: 15749713
    [TBL] [Abstract][Full Text] [Related]  

  • 28. LEDGF/p75-mediated chemoresistance of mixed-lineage leukemia involves cell survival pathways and super enhancer activators.
    Canella A; Van Belle S; Brouns T; Nigita G; Carlon MS; Christ F; Debyser Z
    Cancer Gene Ther; 2022 Feb; 29(2):133-140. PubMed ID: 33795806
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression.
    Messiaen P; De Spiegelaere W; Alcami J; Vervisch K; Van Acker P; Verhasselt B; Meuwissen P; Calonge E; Gonzalez N; Gutierrez-Rodero F; Rodriguez-Martín C; Sermijn E; Poppe B; Vogelaers D; Verhofstede C; Vandekerckhove L
    PLoS One; 2012; 7(11):e50204. PubMed ID: 23226247
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.
    Cherepanov P; Devroe E; Silver PA; Engelman A
    J Biol Chem; 2004 Nov; 279(47):48883-92. PubMed ID: 15371438
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase.
    Llano M; Delgado S; Vanegas M; Poeschla EM
    J Biol Chem; 2004 Dec; 279(53):55570-7. PubMed ID: 15475359
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia.
    Cermáková K; Tesina P; Demeulemeester J; El Ashkar S; Méreau H; Schwaller J; Rezáčová P; Veverka V; De Rijck J
    Cancer Res; 2014 Sep; 74(18):5139-51. PubMed ID: 25082813
    [TBL] [Abstract][Full Text] [Related]  

  • 33. HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.
    Schrijvers R; Vets S; De Rijck J; Malani N; Bushman FD; Debyser Z; Gijsbers R
    Retrovirology; 2012 Oct; 9():84. PubMed ID: 23046603
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.
    Bartholomeeusen K; Christ F; Hendrix J; Rain JC; Emiliani S; Benarous R; Debyser Z; Gijsbers R; De Rijck J
    J Biol Chem; 2009 Apr; 284(17):11467-77. PubMed ID: 19244240
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transcriptional protein Sp1 regulates LEDGF transcription by directly interacting with its cis-elements in GC-rich region of TATA-less gene promoter.
    Singh DP; Bhargavan B; Chhunchha B; Kubo E; Kumar A; Fatma N
    PLoS One; 2012; 7(5):e37012. PubMed ID: 22615874
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering.
    Hendrix J; Gijsbers R; De Rijck J; Voet A; Hotta J; McNeely M; Hofkens J; Debyser Z; Engelborghs Y
    Nucleic Acids Res; 2011 Mar; 39(4):1310-25. PubMed ID: 20974633
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Implication of serine residues 271, 273, and 275 in the human immunodeficiency virus type 1 cofactor activity of lens epithelium-derived growth factor/p75.
    Garcia-Rivera JA; Bueno MT; Morales E; Kugelman JR; Rodriguez DF; Llano M
    J Virol; 2010 Jan; 84(2):740-52. PubMed ID: 19889764
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Lens epithelium-derived growth factor/p75 qualifies as a target for HIV gene therapy in the NSG mouse model.
    Vets S; Kimpel J; Volk A; De Rijck J; Schrijvers R; Verbinnen B; Maes W; Von Laer D; Debyser Z; Gijsbers R
    Mol Ther; 2012 May; 20(5):908-17. PubMed ID: 22334021
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [LEDGF/p75: a novel target for anti-HIV therapy and advances in the study of its related inhibitors].
    Chen WM; Liu XY
    Yao Xue Xue Bao; 2009 Sep; 44(9):953-60. PubMed ID: 20055168
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins.
    Levin A; Rosenbluh J; Hayouka Z; Friedler A; Loyter A
    Mol Med; 2010; 16(1-2):34-44. PubMed ID: 19855849
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.