These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 37057673)

  • 1. De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood.
    Reijnders MRF; Seibt A; Brugger M; Lamers IJC; Ott T; Klaas O; Horváth J; Rose AMS; Craghill IM; Brunet T; Graf E; Mayerhanser K; Hellebrekers D; Pauck D; Neuen-Jacob E; Rodenburg RJT; Wieczorek D; Klee D; Mayatepek E; Driessen G; Bindermann R; Averdunk L; Lohmeier K; Sinnema M; Stegmann APA; Roepman R; Poulter JA; Distelmaier F
    Genet Med; 2023 Jul; 25(7):100838. PubMed ID: 37057673
    [TBL] [Abstract][Full Text] [Related]  

  • 2. De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy.
    Long PA; Zimmermann MT; Kim M; Evans JM; Xu X; Olson TM
    Hum Genet; 2016 Aug; 135(8):909-917. PubMed ID: 27234373
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma.
    Liu Y; Zhu Y; Chen H; Zhou J; Niu P; Shi D
    BMC Complement Med Ther; 2023 Sep; 23(1):336. PubMed ID: 37749558
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagC
    Kim M; Lu L; Dvornikov AV; Ma X; Ding Y; Zhu P; Olson TM; Lin X; Xu X
    Int J Mol Sci; 2021 May; 22(11):. PubMed ID: 34071043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
    Oshiro N; Rapley J; Avruch J
    J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma.
    Ying ZX; Jin M; Peterson LF; Bernard D; Saiya-Cork K; Yildiz M; Wang S; Kaminski MS; Chang AE; Klionsky DJ; Malek SN
    Clin Cancer Res; 2016 Nov; 22(21):5383-5393. PubMed ID: 27267853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.
    Okosun J; Wolfson RL; Wang J; Araf S; Wilkins L; Castellano BM; Escudero-Ibarz L; Al Seraihi AF; Richter J; Bernhart SH; Efeyan A; Iqbal S; Matthews J; Clear A; Guerra-Assunção JA; Bödör C; Quentmeier H; Mansbridge C; Johnson P; Davies A; Strefford JC; Packham G; Barrans S; Jack A; Du MQ; Calaminici M; Lister TA; Auer R; Montoto S; Gribben JG; Siebert R; Chelala C; Zoncu R; Sabatini DM; Fitzgibbon J
    Nat Genet; 2016 Feb; 48(2):183-8. PubMed ID: 26691987
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTOR-Activating Mutations in
    Schlingmann KP; Jouret F; Shen K; Nigam A; Arjona FJ; Dafinger C; Houillier P; Jones DP; Kleinerüschkamp F; Oh J; Godefroid N; Eltan M; Güran T; Burtey S; Parotte MC; König J; Braun A; Bos C; Ibars Serra M; Rehmann H; Zwartkruis FJT; Renkema KY; Klingel K; Schulze-Bahr E; Schermer B; Bergmann C; Altmüller J; Thiele H; Beck BB; Dahan K; Sabatini D; Liebau MC; Vargas-Poussou R; Knoers NVAM; Konrad M; de Baaij JHF
    J Am Soc Nephrol; 2021 Nov; 32(11):2885-2899. PubMed ID: 34607910
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rag GTPase in amino acid signaling.
    Kim J; Kim E
    Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.
    Yoshida S; Hong S; Suzuki T; Nada S; Mannan AM; Wang J; Okada M; Guan KL; Inoki K
    J Biol Chem; 2011 Sep; 286(37):32651-60. PubMed ID: 21784859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
    Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
    Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
    Lin Y; Henderson P; Pettersson S; Satsangi J; Hupp T; Stevens C
    FEBS J; 2011 Jan; 278(2):354-70. PubMed ID: 21134130
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet.
    Kimball SR; Ravi S; Gordon BS; Dennis MD; Jefferson LS
    J Nutr; 2015 Nov; 145(11):2496-502. PubMed ID: 26400964
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RagC phosphorylation autoregulates mTOR complex 1.
    Yang G; Humphrey SJ; Murashige DS; Francis D; Wang QP; Cooke KC; Neely GG; James DE
    EMBO J; 2019 Feb; 38(3):. PubMed ID: 30552228
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rag GTPases are cardioprotective by regulating lysosomal function.
    Kim YC; Park HW; Sciarretta S; Mo JS; Jewell JL; Russell RC; Wu X; Sadoshima J; Guan KL
    Nat Commun; 2014 Jul; 5():4241. PubMed ID: 24980141
    [TBL] [Abstract][Full Text] [Related]  

  • 17. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
    Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
    Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
    Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
    Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation.
    Suryawan A; Davis TA
    J Nutr; 2018 Jun; 148(6):825-833. PubMed ID: 29796625
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.