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5. BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1. Zong D; Gu J; Cavalcante GC; Yao W; Zhang G; Wang S; Owonikoko TK; He X; Sun SY Cancer Res; 2020 Jun; 80(11):2380-2393. PubMed ID: 32156781 [TBL] [Abstract][Full Text] [Related]
6. The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation. Pastori C; Kapranov P; Penas C; Peschansky V; Volmar CH; Sarkaria JN; Bregy A; Komotar R; St Laurent G; Ayad NG; Wahlestedt C Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8326-31. PubMed ID: 26111795 [TBL] [Abstract][Full Text] [Related]
7. Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma. Xu L; Chen Y; Mayakonda A; Koh L; Chong YK; Buckley DL; Sandanaraj E; Lim SW; Lin RY; Ke XY; Huang ML; Chen J; Sun W; Wang LZ; Goh BC; Dinh HQ; Kappei D; Winter GE; Ding LW; Ang BT; Berman BP; Bradner JE; Tang C; Koeffler HP Proc Natl Acad Sci U S A; 2018 May; 115(22):E5086-E5095. PubMed ID: 29764999 [TBL] [Abstract][Full Text] [Related]
8. Systematic analysis of the BET family in adrenocortical carcinoma: The expression, prognosis, gene regulation network, and regulation targets. Situ Y; Liang Q; Zeng Z; Chen J; Shao Z; Xu Q; Lu X; Cui Y; Zhang J; Lu L; Deng L Front Endocrinol (Lausanne); 2023; 14():1089531. PubMed ID: 36793283 [TBL] [Abstract][Full Text] [Related]
9. BRD4 degraders may effectively counteract therapeutic resistance of leukemic stem cells in AML and ALL. Bauer K; Hauswirth A; Gleixner KV; Greiner G; Thaler J; Bettelheim P; Filik Y; Koller E; Hoermann G; Staber PB; Sperr WR; Keil F; Valent P Am J Hematol; 2024 Sep; 99(9):1721-1731. PubMed ID: 38822666 [TBL] [Abstract][Full Text] [Related]
11. Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression. Dai J; Zhou S; Ge Q; Qin J; Li J; Ju H; Cao Y; Zheng M; Li C; Gao X; Teng H; Jiang Q J Orthop Surg Res; 2019 Feb; 14(1):59. PubMed ID: 30786900 [TBL] [Abstract][Full Text] [Related]
12. Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression. Gao Z; Yuan T; Zhou X; Ni P; Sun G; Li P; Cheng Z; Wang X Cancer Biol Ther; 2018 May; 19(5):407-415. PubMed ID: 29333921 [TBL] [Abstract][Full Text] [Related]
14. A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma. Kling MJ; Kesherwani V; Mishra NK; Alexander G; McIntyre EM; Ray S; Challagundla KB; Joshi SS; Coulter DW; Chaturvedi NK J Exp Clin Cancer Res; 2022 Nov; 41(1):321. PubMed ID: 36357906 [TBL] [Abstract][Full Text] [Related]
15. Enhanced efficacy of histone deacetylase inhibitor combined with bromodomain inhibitor in glioblastoma. Meng W; Wang B; Mao W; Wang J; Zhao Y; Li Q; Zhang C; Tang Y; Ma J J Exp Clin Cancer Res; 2018 Oct; 37(1):241. PubMed ID: 30285808 [TBL] [Abstract][Full Text] [Related]
16. BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity. Khoueiry P; Ward Gahlawat A; Petretich M; Michon AM; Simola D; Lam E; Furlong EE; Benes V; Dawson MA; Prinjha RK; Drewes G; Grandi P Epigenetics Chromatin; 2019 Jul; 12(1):39. PubMed ID: 31266503 [TBL] [Abstract][Full Text] [Related]
17. BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes. Wu S; Jiang Y; Hong Y; Chu X; Zhang Z; Tao Y; Fan Z; Bai Z; Li X; Chen Y; Li Z; Ding X; Lv H; Du X; Lim SL; Zhang Y; Huang S; Lu J; Pan J; Hu S Cancer Cell Int; 2021 Apr; 21(1):230. PubMed ID: 33888130 [TBL] [Abstract][Full Text] [Related]
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19. MZ1, a BRD4 inhibitor, exerted its anti-cancer effects by suppressing SDC1 in glioblastoma. Li G; Ma L; Feng C; Yin H; Bao J; Wu D; Zhang Z; Li X; Li Z; Yang C; Wang H; Fang F; Hu X; Li M; Xu L; Xu Y; Liang H; Yang T; Wang J; Pan J BMC Cancer; 2024 Feb; 24(1):220. PubMed ID: 38365636 [TBL] [Abstract][Full Text] [Related]
20. Degradation of BRD4 - a promising treatment approach not only for hematologic but also for solid cancer. Bauer K; Berghoff AS; Preusser M; Heller G; Zielinski CC; Valent P; Grunt TW Am J Cancer Res; 2021; 11(2):530-545. PubMed ID: 33575085 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]