149 related articles for article (PubMed ID: 37068727)
1. Identification of molecular initiating events (MIE) using chemical database analysis and nuclear receptor activity assays for screening potential inhalation toxicants.
Jeong J; Kim J; Choi J
Regul Toxicol Pharmacol; 2023 Jun; 141():105391. PubMed ID: 37068727
[TBL] [Abstract][Full Text] [Related]
2. Identification of toxicity pathway of diesel particulate matter using AOP of PPARγ inactivation leading to pulmonary fibrosis.
Jeong J; Bae SY; Choi J
Environ Int; 2021 Feb; 147():106339. PubMed ID: 33422967
[TBL] [Abstract][Full Text] [Related]
3. Development of Adverse Outcome Pathway for PPARγ Antagonism Leading to Pulmonary Fibrosis and Chemical Selection for Its Validation: ToxCast Database and a Deep Learning Artificial Neural Network Model-Based Approach.
Jeong J; Garcia-Reyero N; Burgoon L; Perkins E; Park T; Kim C; Roh JY; Choi J
Chem Res Toxicol; 2019 Jun; 32(6):1212-1222. PubMed ID: 31074622
[TBL] [Abstract][Full Text] [Related]
4. Advancing the Adverse Outcome Pathway for PPARγ Inactivation Leading to Pulmonary Fibrosis Using Bradford-Hill Consideration and the Comparative Toxicogenomics Database.
Jeong J; Choi J
Chem Res Toxicol; 2022 Feb; 35(2):233-243. PubMed ID: 35143163
[TBL] [Abstract][Full Text] [Related]
5. The application of molecular modelling in the safety assessment of chemicals: A case study on ligand-dependent PPARγ dysregulation.
Al Sharif M; Tsakovska I; Pajeva I; Alov P; Fioravanzo E; Bassan A; Kovarich S; Yang C; Mostrag-Szlichtyng A; Vitcheva V; Worth AP; Richarz AN; Cronin MTD
Toxicology; 2017 Dec; 392():140-154. PubMed ID: 26836498
[TBL] [Abstract][Full Text] [Related]
6. A toxicity pathway-oriented approach to develop adverse outcome pathway: AHR activation as a case study.
Jin Y; Feng M; Ma W; Wei Y; Qi G; Luo J; Xu L; Li X; Li C; Wang Y; Li D; Chen J; Zhao Y; Hou Y; Zhao Q; Jiang L; Xie M; Zheng Y; Yu D
Environ Pollut; 2021 Jan; 268(Pt B):115733. PubMed ID: 33011576
[TBL] [Abstract][Full Text] [Related]
7. AOP-helpFinder 2.0: Integration of an event-event searches module.
Jaylet T; Coustillet T; Jornod F; Margaritte-Jeannin P; Audouze K
Environ Int; 2023 Jul; 177():108017. PubMed ID: 37295163
[TBL] [Abstract][Full Text] [Related]
8. AOPERA: A proposed methodology and inventory of effective tools to link chemicals to adverse outcome pathways.
Rycroft TE; Foran CM; Thrash A; Cegan JC; Zollinger R; Linkov I; Perkins EJ; Garcia-Reyero N
ALTEX; 2020; 37(1):64-74. PubMed ID: 31453632
[TBL] [Abstract][Full Text] [Related]
9. An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis.
Negi CK; Bajard L; Kohoutek J; Blaha L
Environ Pollut; 2021 Nov; 289():117855. PubMed ID: 34340181
[TBL] [Abstract][Full Text] [Related]
10. Molecular modelling study of the PPARγ receptor in relation to the mode of action/adverse outcome pathway framework for liver steatosis.
Tsakovska I; Al Sharif M; Alov P; Diukendjieva A; Fioravanzo E; Cronin MT; Pajeva I
Int J Mol Sci; 2014 May; 15(5):7651-66. PubMed ID: 24857909
[TBL] [Abstract][Full Text] [Related]
11. Novel QSAR Models for Molecular Initiating Event Modeling in Two Intersecting Adverse Outcome Pathways Based Pulmonary Fibrosis Prediction for Biocidal Mixtures.
Seo M; Chae CH; Lee Y; Kim HR; Kim J
Toxics; 2021 Mar; 9(3):. PubMed ID: 33809804
[TBL] [Abstract][Full Text] [Related]
12. Integrative Data Mining Approach: Case Study with Adverse Outcome Pathway Network Leading to Pulmonary Fibrosis.
Jeong J; Kim D; Choi J
Chem Res Toxicol; 2023 Jun; 36(6):838-847. PubMed ID: 37093963
[TBL] [Abstract][Full Text] [Related]
13. When Are Adverse Outcome Pathways and Associated Assays "Fit for Purpose" for Regulatory Decision-Making and Management of Chemicals?
Coady K; Browne P; Embry M; Hill T; Leinala E; Steeger T; Maślankiewicz L; Hutchinson T
Integr Environ Assess Manag; 2019 Jul; 15(4):633-647. PubMed ID: 30908812
[TBL] [Abstract][Full Text] [Related]
14. A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions.
Nelms MD; Mellor CL; Enoch SJ; Judson RS; Patlewicz G; Richard AM; Madden JM; Cronin MTD; Edwards SW
Comput Toxicol; 2018 Nov; 8():1-12. PubMed ID: 36779220
[TBL] [Abstract][Full Text] [Related]
15. An In vitro dimerization assay for the adverse outcome pathway approach in risk assessment of human estrogen receptor α-mediated endocrine-disrupting chemicals.
Lee SH; Seo H; Seo H; Lazari M; D'Agostino M; Byrd N; Yoon KS; Lee HS; Park Y
Chemosphere; 2022 Mar; 290():133267. PubMed ID: 34914963
[TBL] [Abstract][Full Text] [Related]
16. Example of Adverse Outcome Pathway Concept Enabling Genome-to-Phenome Discovery in Toxicology.
Gust KA; Ji Q; Luo X
Integr Comp Biol; 2020 Aug; 60(2):375-384. PubMed ID: 32516358
[TBL] [Abstract][Full Text] [Related]
17. A strategy towards the generation of testable adverse outcome pathways for nanomaterials.
Murugadoss S; Vinković Vrček I; Pem B; Jagiello K; Judzinska B; Sosnowska A; Martens M; Willighagen EL; Puzyn T; Dusinska M; Cimpan MR; Fessard V; Hoet PH
ALTEX; 2021; 38(4):580-594. PubMed ID: 34008034
[TBL] [Abstract][Full Text] [Related]
18. Optimization of an adverse outcome pathway network on chemical-induced cholestasis using an artificial intelligence-assisted data collection and confidence level quantification approach.
van Ertvelde J; Verhoeven A; Maerten A; Cooreman A; Santos Rodrigues BD; Sanz-Serrano J; Mihajlovic M; Tripodi I; Teunis M; Jover R; Luechtefeld T; Vanhaecke T; Jiang J; Vinken M
J Biomed Inform; 2023 Sep; 145():104465. PubMed ID: 37541407
[TBL] [Abstract][Full Text] [Related]
19. Advancing the adverse outcome pathway framework-An international horizon scanning approach.
LaLone CA; Ankley GT; Belanger SE; Embry MR; Hodges G; Knapen D; Munn S; Perkins EJ; Rudd MA; Villeneuve DL; Whelan M; Willett C; Zhang X; Hecker M
Environ Toxicol Chem; 2017 Jun; 36(6):1411-1421. PubMed ID: 28543973
[TBL] [Abstract][Full Text] [Related]
20. Adverse outcome pathway: a path toward better data consolidation and global co-ordination of radiation research.
Chauhan V; Beaton D; Hamada N; Wilkins R; Burtt J; Leblanc J; Cool D; Garnier-Laplace J; Laurier D; Le Y; Yamada Y; Tollefsen KE
Int J Radiat Biol; 2022; 98(12):1694-1703. PubMed ID: 34919011
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]