These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells. Leskelä S; Huber N; Hoffmann D; Rostalski H; Remes AM; Takalo M; Hiltunen M; Haapasalo A Biochim Biophys Acta Mol Cell Res; 2021 Jun; 1868(7):119021. PubMed ID: 33775797 [TBL] [Abstract][Full Text] [Related]
23. CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro. Meijboom KE; Abdallah A; Fordham NP; Nagase H; Rodriguez T; Kraus C; Gendron TF; Krishnan G; Esanov R; Andrade NS; Rybin MJ; Ramic M; Stephens ZD; Edraki A; Blackwood MT; Kahriman A; Henninger N; Kocher JA; Benatar M; Brodsky MH; Petrucelli L; Gao FB; Sontheimer EJ; Brown RH; Zeier Z; Mueller C Nat Commun; 2022 Oct; 13(1):6286. PubMed ID: 36271076 [TBL] [Abstract][Full Text] [Related]
28. Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases. Dedeene L; Van Schoor E; Vandenberghe R; Van Damme P; Poesen K; Thal DR Acta Neuropathol Commun; 2019 Dec; 7(1):189. PubMed ID: 31791419 [TBL] [Abstract][Full Text] [Related]
29. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress. Zhang YJ; Jansen-West K; Xu YF; Gendron TF; Bieniek KF; Lin WL; Sasaguri H; Caulfield T; Hubbard J; Daughrity L; Chew J; Belzil VV; Prudencio M; Stankowski JN; Castanedes-Casey M; Whitelaw E; Ash PE; DeTure M; Rademakers R; Boylan KB; Dickson DW; Petrucelli L Acta Neuropathol; 2014 Oct; 128(4):505-24. PubMed ID: 25173361 [TBL] [Abstract][Full Text] [Related]
30. The Genetics of Gijselinck I; Cruts M; Van Broeckhoven C Cold Spring Harb Perspect Med; 2018 Apr; 8(4):. PubMed ID: 28130313 [TBL] [Abstract][Full Text] [Related]
31. Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion. Waite AJ; Bäumer D; East S; Neal J; Morris HR; Ansorge O; Blake DJ Neurobiol Aging; 2014 Jul; 35(7):1779.e5-1779.e13. PubMed ID: 24559645 [TBL] [Abstract][Full Text] [Related]
33. Frequency of C9orf72 hexanucleotide repeat expansion and SOD1 mutations in Portuguese patients with amyotrophic lateral sclerosis. Gromicho M; Pinto S; Gisca E; Pronto-Laborinho AC; Andersen PM; de Carvalho M Neurobiol Aging; 2018 Oct; 70():325.e7-325.e15. PubMed ID: 29861044 [TBL] [Abstract][Full Text] [Related]
34. C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Fratta P; Mizielinska S; Nicoll AJ; Zloh M; Fisher EM; Parkinson G; Isaacs AM Sci Rep; 2012; 2():1016. PubMed ID: 23264878 [TBL] [Abstract][Full Text] [Related]
35. Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies. Davidson YS; Robinson AC; Rollinson S; Pickering-Brown S; Xiao S; Robertson J; Mann DMA Amyotroph Lateral Scler Frontotemporal Degener; 2018 Feb; 19(1-2):102-111. PubMed ID: 28766957 [TBL] [Abstract][Full Text] [Related]
36. C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia: gain or loss of function? Mizielinska S; Isaacs AM Curr Opin Neurol; 2014 Oct; 27(5):515-23. PubMed ID: 25188012 [TBL] [Abstract][Full Text] [Related]
37. C9ORF72, the new gene on the block, causes C9FTD/ALS: new insights provided by neuropathology. Bigio EH Acta Neuropathol; 2011 Dec; 122(6):653-5. PubMed ID: 22101324 [No Abstract] [Full Text] [Related]
38. Screening for C9orf72 repeat expansions in Chinese amyotrophic lateral sclerosis patients. Zou ZY; Li XG; Liu MS; Cui LY Neurobiol Aging; 2013 Jun; 34(6):1710.e5-6. PubMed ID: 23261768 [TBL] [Abstract][Full Text] [Related]
39. How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders? van Blitterswijk M; DeJesus-Hernandez M; Rademakers R Curr Opin Neurol; 2012 Dec; 25(6):689-700. PubMed ID: 23160421 [TBL] [Abstract][Full Text] [Related]
40. C9ORF72-ALS/FTD: Transgenic Mice Make a Come-BAC. Hayes LR; Rothstein JD Neuron; 2016 May; 90(3):427-31. PubMed ID: 27151634 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]