BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 37082953)

  • 1. The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.
    Lin H; Cossu IG; Leu NA; Deshpande AJ; Bernt KM; Luo M; Wang PJ
    Development; 2023 May; 150(9):. PubMed ID: 37082953
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement.
    Malla AB; Rainsford SR; Smith ZD; Lesch BJ
    Development; 2023 May; 150(9):. PubMed ID: 37082969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DOT1L regulates chromatin reorganization and gene expression during sperm differentiation.
    Blanco M; El Khattabi L; Gobé C; Crespo M; Coulée M; de la Iglesia A; Ialy-Radio C; Lapoujade C; Givelet M; Delessard M; Seller-Corona I; Yamaguchi K; Vernet N; Van Leeuwen F; Lermine A; Okada Y; Daveau R; Oliva R; Fouchet P; Ziyyat A; Pflieger D; Cocquet J
    EMBO Rep; 2023 Jun; 24(6):e56316. PubMed ID: 37099396
    [TBL] [Abstract][Full Text] [Related]  

  • 4. H3K79 methylation directly precedes the histone-to-protamine transition in mammalian spermatids and is sensitive to bacterial infections.
    Dottermusch-Heidel C; Klaus ES; Gonzalez NH; Bhushan S; Meinhardt A; Bergmann M; Renkawitz-Pohl R; Rathke C; Steger K
    Andrology; 2014 Sep; 2(5):655-65. PubMed ID: 25079683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.
    Mahmoudi T; Boj SF; Hatzis P; Li VS; Taouatas N; Vries RG; Teunissen H; Begthel H; Korving J; Mohammed S; Heck AJ; Clevers H
    PLoS Biol; 2010 Nov; 8(11):e1000539. PubMed ID: 21103407
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
    Jones B; Su H; Bhat A; Lei H; Bajko J; Hevi S; Baltus GA; Kadam S; Zhai H; Valdez R; Gonzalo S; Zhang Y; Li E; Chen T
    PLoS Genet; 2008 Sep; 4(9):e1000190. PubMed ID: 18787701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Maternal DOT1L is dispensable for mouse development.
    Liao J; Szabó PE
    Sci Rep; 2020 Nov; 10(1):20636. PubMed ID: 33244015
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer.
    Yang L; Lei Q; Li L; Yang J; Dong Z; Cui H
    Clin Epigenetics; 2019 Dec; 11(1):199. PubMed ID: 31888761
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.
    FitzGerald J; Moureau S; Drogaris P; O'Connell E; Abshiru N; Verreault A; Thibault P; Grenon M; Lowndes NF
    PLoS One; 2011 Feb; 6(2):e14714. PubMed ID: 21383990
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
    Ho LL; Sinha A; Verzi M; Bernt KM; Armstrong SA; Shivdasani RA
    Mol Cell Biol; 2013 May; 33(9):1735-45. PubMed ID: 23428873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation.
    Uğurlu-Çimen D; Odluyurt D; Sevinç K; Özkan-Küçük NE; Özçimen B; Demirtaş D; Enüstün E; Aztekin C; Philpott M; Oppermann U; Özlü N; Önder TT
    Epigenetics Chromatin; 2021 Jul; 14(1):32. PubMed ID: 34215314
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes.
    Ontoso D; Kauppi L; Keeney S; San-Segundo PA
    Chromosoma; 2014 Mar; 123(1-2):147-64. PubMed ID: 24105599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
    Steger DJ; Lefterova MI; Ying L; Stonestrom AJ; Schupp M; Zhuo D; Vakoc AL; Kim JE; Chen J; Lazar MA; Blobel GA; Vakoc CR
    Mol Cell Biol; 2008 Apr; 28(8):2825-39. PubMed ID: 18285465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages.
    Chen X; Liu X; Zhang Y; Huai W; Zhou Q; Xu S; Chen X; Li N; Cao X
    Cell Mol Immunol; 2020 Jan; 17(1):76-84. PubMed ID: 30275539
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.
    Wang F; Ngo J; Li Y; Liu H; Chen CH; Saifudeen Z; Sequeira-Lopez MLS; El-Dahr SS
    Epigenetics; 2021 Nov; 16(11):1235-1250. PubMed ID: 33315499
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation.
    Kim W; Kim R; Park G; Park JW; Kim JE
    J Biol Chem; 2012 Feb; 287(8):5588-99. PubMed ID: 22190683
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity.
    Wille CK; Neumann EN; Deshpande AJ; Sridharan R
    Stem Cell Reports; 2023 Dec; 18(12):2451-2463. PubMed ID: 37995701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.
    Wang WT; Chen TQ; Zeng ZC; Pan Q; Huang W; Han C; Fang K; Sun LY; Yang QQ; Wang D; Luo XQ; Sun YM; Chen YQ
    J Hematol Oncol; 2020 Jun; 13(1):78. PubMed ID: 32552847
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2.
    Whitcomb SJ; Fierz B; McGinty RK; Holt M; Ito T; Muir TW; Allis CD
    J Biol Chem; 2012 Jul; 287(28):23718-25. PubMed ID: 22619169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development.
    Ogoh H; Yamagata K; Nakao T; Sandell LL; Yamamoto A; Yamashita A; Tanga N; Suzuki M; Abe T; Kitabayashi I; Watanabe T; Sakai D
    Sci Rep; 2017 Sep; 7(1):11922. PubMed ID: 28931923
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.