Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 37086156)

  • 1. Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer.
    Gonthier K; Weidmann C; Berthiaume L; Jobin C; Lacouture A; Lafront C; Harvey M; Neveu B; Loehr J; Bergeron A; Fradet Y; Lacombe L; Riopel J; Latulippe É; Atallah C; Shum M; Lambert JP; Pouliot F; Pelletier M; Audet-Walsh É
    Mol Oncol; 2023 Oct; 17(10):2109-2125. PubMed ID: 37086156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reprogramming of Isocitrate Dehydrogenases Expression and Activity by the Androgen Receptor in Prostate Cancer.
    Gonthier K; Poluri RTK; Weidmann C; Tadros M; Audet-Walsh É
    Mol Cancer Res; 2019 Aug; 17(8):1699-1709. PubMed ID: 31068457
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.
    MacDonald MJ; Brown LJ; Longacre MJ; Stoker SW; Kendrick MA; Hasan NM
    Biochim Biophys Acta; 2013 Nov; 1830(11):5104-11. PubMed ID: 23876293
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism.
    Grassian AR; Parker SJ; Davidson SM; Divakaruni AS; Green CR; Zhang X; Slocum KL; Pu M; Lin F; Vickers C; Joud-Caldwell C; Chung F; Yin H; Handly ED; Straub C; Growney JD; Vander Heiden MG; Murphy AN; Pagliarini R; Metallo CM
    Cancer Res; 2014 Jun; 74(12):3317-31. PubMed ID: 24755473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.
    Wen H; Cho HR; Yun T; Kim H; Park CK; Lee SH; Choi SH; Park S
    J Neurochem; 2015 Jan; 132(2):183-93. PubMed ID: 25251602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological inhibition of androgen receptor expression induces cell death in prostate cancer cells.
    Song IS; Jeong YJ; Kim J; Seo KH; Baek NI; Kim Y; Kim CS; Jang SW
    Cell Mol Life Sci; 2020 Nov; 77(22):4663-4673. PubMed ID: 31894360
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging drug profile: Krebs cycle and cancer: IDH mutations and therapeutic implications.
    Lee S; Urman A; Desai P
    Leuk Lymphoma; 2019 Nov; 60(11):2635-2645. PubMed ID: 30958073
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
    Bader DA; Hartig SM; Putluri V; Foley C; Hamilton MP; Smith EA; Saha PK; Panigrahi A; Walker C; Zong L; Martini-Stoica H; Chen R; Rajapakshe K; Coarfa C; Sreekumar A; Mitsiades N; Bankson JA; Ittmann MM; O'Malley BW; Putluri N; McGuire SE
    Nat Metab; 2019 Jan; 1(1):70-85. PubMed ID: 31198906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.
    Ward PS; Lu C; Cross JR; Abdel-Wahab O; Levine RL; Schwartz GK; Thompson CB
    J Biol Chem; 2013 Feb; 288(6):3804-15. PubMed ID: 23264629
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cloning and characterization of the gene encoding the IDH1 subunit of NAD(+)-dependent isocitrate dehydrogenase from Saccharomyces cerevisiae.
    Cupp JR; McAlister-Henn L
    J Biol Chem; 1992 Aug; 267(23):16417-23. PubMed ID: 1644826
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wild-type IDH1 Knockout Leads to G0/G1 Arrest, Impairs Cancer Cell Proliferation, Altering Glycolysis, and the TCA Cycle in Colon Cancer.
    Atalay EB; Senturk S; Kayali HA
    Biochem Genet; 2023 Aug; 61(4):1470-1486. PubMed ID: 36633771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer.
    Lee YG; Nam Y; Shin KJ; Yoon S; Park WS; Joung JY; Seo JK; Jang J; Lee S; Nam D; Caino MC; Suh PG; Chan Chae Y
    Cancer Lett; 2020 Feb; 471():72-87. PubMed ID: 31838085
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation.
    Zhou L; Wang Z; Hu C; Zhang C; Kovatcheva-Datchary P; Yu D; Liu S; Ren F; Wang X; Li Y; Hou X; Piao H; Lu X; Zhang Y; Xu G
    J Proteome Res; 2019 Mar; 18(3):960-969. PubMed ID: 30596429
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IDH3α regulates one-carbon metabolism in glioblastoma.
    May JL; Kouri FM; Hurley LA; Liu J; Tommasini-Ghelfi S; Ji Y; Gao P; Calvert AE; Lee A; Chandel NS; Davuluri RV; Horbinski CM; Locasale JW; Stegh AH
    Sci Adv; 2019 Jan; 5(1):eaat0456. PubMed ID: 30613765
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Androgen receptor reverses the oncometabolite R-2-hydroxyglutarate-induced prostate cancer cell invasion via suppressing the circRNA-51217/miRNA-646/TGFβ1/p-Smad2/3 signaling.
    Xu H; Sun Y; You B; Huang CP; Ye D; Chang C
    Cancer Lett; 2020 Mar; 472():151-164. PubMed ID: 31846689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
    Chotirat S; Thongnoppakhun W; Promsuwicha O; Boonthimat C; Auewarakul CU
    J Hematol Oncol; 2012 Mar; 5():5. PubMed ID: 22397365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
    Jiang L; Shestov AA; Swain P; Yang C; Parker SJ; Wang QA; Terada LS; Adams ND; McCabe MT; Pietrak B; Schmidt S; Metallo CM; Dranka BP; Schwartz B; DeBerardinis RJ
    Nature; 2016 Apr; 532(7598):255-8. PubMed ID: 27049945
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reductive TCA cycle catalyzed by wild-type IDH2 promotes acute myeloid leukemia and is a metabolic vulnerability for potential targeted therapy.
    Zeng P; Lu W; Tian J; Qiao S; Li J; Glorieux C; Wen S; Zhang H; Li Y; Huang P
    J Hematol Oncol; 2022 Mar; 15(1):30. PubMed ID: 35313945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PAX5-induced upregulation of IDH1-AS1 promotes tumor growth in prostate cancer by regulating ATG5-mediated autophagy.
    Zhang N; Li Z; Bai F; Zhang S
    Cell Death Dis; 2019 Sep; 10(10):734. PubMed ID: 31570703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two phenotypically compensating isocitrate dehydrogenases in Ralstonia eutropha.
    Wang ZX; Brämer C; Steinbüchel A
    FEMS Microbiol Lett; 2003 Oct; 227(1):9-16. PubMed ID: 14568142
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.