BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 37087895)

  • 1. Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells.
    Wang H; Wang C; Li B; Zheng C; Liu G; Liu Z; Zhang L; Xu P
    Eur J Med Chem; 2023 Jun; 254():115343. PubMed ID: 37087895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A potent GPX4 degrader to induce ferroptosis in HT1080 cells.
    Song H; Liang J; Guo Y; Liu Y; Sa K; Yan G; Xu W; Xu W; Chen L; Li H
    Eur J Med Chem; 2024 Feb; 265():116110. PubMed ID: 38194774
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders.
    Li X; Hu M; Zhang Y; Hua H; Sun Y; Xiang Q; Zhu D
    Bioorg Chem; 2024 Mar; 144():107115. PubMed ID: 38232684
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual degradation mechanism of GPX4 degrader in induction of ferroptosis exerting anti-resistant tumor effect.
    Wang C; Zheng C; Wang H; Shui S; Jin H; Liu G; Xu F; Liu Z; Zhang L; Sun D; Xu P
    Eur J Med Chem; 2023 Feb; 247():115072. PubMed ID: 36603510
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery and optimization of indirubin derivatives as novel ferroptosis inducers for the treatment of colon cancer.
    Zhu JM; Chen C; Kong M; Zhu L; Li YL; Zhang JF; Yu ZP; Xu SS; Kong LY; Luo JG
    Eur J Med Chem; 2023 Dec; 261():115829. PubMed ID: 37801824
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prospects for Anti-Tumor Mechanism and Potential Clinical Application Based on Glutathione Peroxidase 4 Mediated Ferroptosis.
    Chen M; Shi Z; Sun Y; Ning H; Gu X; Zhang L
    Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36675129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Significance of glutathione peroxidase 4 and intracellular iron level in ovarian cancer cells-"utilization" of ferroptosis mechanism.
    Li D; Zhang M; Chao H
    Inflamm Res; 2021 Dec; 70(10-12):1177-1189. PubMed ID: 34537856
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization.
    Zheng C; Wang C; Sun D; Wang H; Li B; Liu G; Liu Z; Zhang L; Xu P
    Eur J Med Chem; 2023 Jul; 255():115393. PubMed ID: 37098297
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular Delivery of Glutathione Peroxidase Degrader Induces Ferroptosis In Vivo.
    Luo T; Zheng Q; Shao L; Ma T; Mao L; Wang M
    Angew Chem Int Ed Engl; 2022 Sep; 61(39):e202206277. PubMed ID: 35924720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of proteolysis-targeting chimeras (PROTACs) as degraders of glutathione peroxidase 4.
    Cai M; Ma F; Hu C; Li H; Cao F; Li Y; Dong J; Qin JJ
    Bioorg Med Chem; 2023 Jul; 90():117352. PubMed ID: 37257255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting GPX4 in human cancer: Implications of ferroptosis induction for tackling cancer resilience.
    Lee J; Roh JL
    Cancer Lett; 2023 Apr; 559():216119. PubMed ID: 36893895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ZX703: A Small-Molecule Degrader of GPX4 Inducing Ferroptosis in Human Cancer Cells.
    Hu M; Li X; Wang L; Zhang Y; Sun Y; Hua H; Liu H; Cai T; Zhu D; Xiang Q
    ACS Med Chem Lett; 2024 Mar; 15(3):406-412. PubMed ID: 38505849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent nanoreactor-mediated ferroptosis-based strategy for the reversal of cancer chemoresistance to Sorafenib.
    Wang X; Zhao L; Wang C; Wang L; Wu H; Song X; Wang W; Xu H; Dong X
    Acta Biomater; 2023 Mar; 159():237-246. PubMed ID: 36736851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer.
    Chen T; Leng J; Tan J; Zhao Y; Xie S; Zhao S; Yan X; Zhu L; Luo J; Kong L; Yin Y
    J Med Chem; 2023 Jul; 66(14):10036-10059. PubMed ID: 37452764
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1.
    Cheff DM; Huang C; Scholzen KC; Gencheva R; Ronzetti MH; Cheng Q; Hall MD; Arnér ESJ
    Redox Biol; 2023 Jun; 62():102703. PubMed ID: 37087975
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells.
    Peng C; Fu X; Wang K; Chen L; Luo B; Huang N; Luo Y; Chen W
    Eur J Pharmacol; 2022 Jan; 914():174461. PubMed ID: 34469757
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GPX4: The hub of lipid oxidation, ferroptosis, disease and treatment.
    Liu Y; Wan Y; Jiang Y; Zhang L; Cheng W
    Biochim Biophys Acta Rev Cancer; 2023 May; 1878(3):188890. PubMed ID: 37001616
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis.
    Imai H; Matsuoka M; Kumagai T; Sakamoto T; Koumura T
    Curr Top Microbiol Immunol; 2017; 403():143-170. PubMed ID: 28204974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death.
    Krümmel B; Plötz T; Jörns A; Lenzen S; Mehmeti I
    Biochim Biophys Acta Mol Basis Dis; 2021 Jun; 1867(6):166114. PubMed ID: 33662571
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer.
    Sekhar KR; Hanna DN; Cyr S; Baechle JJ; Kuravi S; Balusu R; Rathmell K; Baregamian N
    Sci Rep; 2022 Nov; 12(1):19396. PubMed ID: 36371529
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.