BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 37100771)

  • 1. Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F.
    Ivanchenko MV; Hathaway DM; Klein AJ; Pan B; Strelkova O; De-la-Torre P; Wu X; Peters CW; Mulhall EM; Booth KT; Goldstein C; Brower J; Sotomayor M; Indzhykulian AA; Corey DP
    Nat Commun; 2023 Apr; 14(1):2400. PubMed ID: 37100771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.
    Peters CW; Hanlon KS; Ivanchenko MV; Zinn E; Linarte EF; Li Y; Levy JM; Liu DR; Kleinstiver BP; Indzhykulian AA; Corey DP
    Mol Ther; 2023 Aug; 31(8):2439-2453. PubMed ID: 37312453
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elasticity and Thermal Stability are Key Determinants of Hearing Rescue by Mini-Protocadherin-15 Proteins.
    Pedro De-la-Torre ; Wen H; Brower J; Martínez-Pérez K; Narui Y; Yeh F; Hale E; Ivanchenko MV; Corey DP; Sotomayor M; Indzhykulian AA
    bioRxiv; 2024 Jun; ():. PubMed ID: 38948700
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PCDH15 Dual-AAV Gene Therapy for Deafness and Blindness in Usher Syndrome Type 1F.
    Ivanchenko MV; Hathaway DM; Mulhall EM; Booth KT; Wang M; Peters CW; Klein AJ; Chen X; Li Y; György B; Corey DP
    bioRxiv; 2023 Nov; ():. PubMed ID: 38014037
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual AAV-based PCDH15 gene therapy achieves sustained rescue of visual function in a mouse model of Usher syndrome 1F.
    Riaz S; Sethna S; Duncan T; Naeem MA; Redmond TM; Riazuddin S; Riazuddin S; Carvalho LS; Ahmed ZM
    Mol Ther; 2023 Dec; 31(12):3490-3501. PubMed ID: 37864333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain.
    Webb SW; Grillet N; Andrade LR; Xiong W; Swarthout L; Della Santina CC; Kachar B; Müller U
    Development; 2011 Apr; 138(8):1607-17. PubMed ID: 21427143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells.
    Geng R; Sotomayor M; Kinder KJ; Gopal SR; Gerka-Stuyt J; Chen DH; Hardisty-Hughes RE; Ball G; Parker A; Gaudet R; Furness D; Brown SD; Corey DP; Alagramam KN
    J Neurosci; 2013 Mar; 33(10):4395-404. PubMed ID: 23467356
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proposed therapy, developed in a
    Sethna S; Zein WM; Riaz S; Giese AP; Schultz JM; Duncan T; Hufnagel RB; Brewer CC; Griffith AJ; Redmond TM; Riazuddin S; Friedman TB; Ahmed ZM
    Elife; 2021 Nov; 10():. PubMed ID: 34751129
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Case report: novel PCDH15 variant causes usher syndrome type 1F with congenital hearing loss and syndromic retinitis pigmentosa.
    Chen N; Lee H; Kim AH; Liu PK; Kang EY; Tseng YJ; Seo GH; Khang R; Liu L; Chen KJ; Wu WC; Hsiao MC; Wang NK
    BMC Ophthalmol; 2022 Nov; 22(1):441. PubMed ID: 36384460
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tuning Inner-Ear Tip-Link Affinity Through Alternatively Spliced Variants of Protocadherin-15.
    Narui Y; Sotomayor M
    Biochemistry; 2018 Mar; 57(11):1702-1710. PubMed ID: 29443515
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells.
    Pepermans E; Michel V; Goodyear R; Bonnet C; Abdi S; Dupont T; Gherbi S; Holder M; Makrelouf M; Hardelin JP; Marlin S; Zenati A; Richardson G; Avan P; Bahloul A; Petit C
    EMBO Mol Med; 2014 Jul; 6(7):984-92. PubMed ID: 24940003
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Usher protein functions in hair cells and photoreceptors.
    Cosgrove D; Zallocchi M
    Int J Biochem Cell Biol; 2014 Jan; 46():80-9. PubMed ID: 24239741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.
    Kazmierczak P; Sakaguchi H; Tokita J; Wilson-Kubalek EM; Milligan RA; Müller U; Kachar B
    Nature; 2007 Sep; 449(7158):87-91. PubMed ID: 17805295
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation screening of the PCDH15 gene in Spanish patients with Usher syndrome type I.
    Jaijo T; Oshima A; Aller E; Carney C; Usami S; Millán JM; Kimberling WJ
    Mol Vis; 2012; 18():1719-26. PubMed ID: 22815625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ames Waltzer deaf mice have reduced electroretinogram amplitudes and complex alternative splicing of Pcdh15 transcripts.
    Haywood-Watson RJ; Ahmed ZM; Kjellstrom S; Bush RA; Takada Y; Hampton LL; Battey JF; Sieving PA; Friedman TB
    Invest Ophthalmol Vis Sci; 2006 Jul; 47(7):3074-84. PubMed ID: 16799054
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Progression of inner ear pathology in Ames waltzer mice and the role of protocadherin 15 in hair cell development.
    Pawlowski KS; Kikkawa YS; Wright CG; Alagramam KN
    J Assoc Res Otolaryngol; 2006 Jun; 7(2):83-94. PubMed ID: 16408167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the Kyoto circling (KCI) rat carrying a spontaneous nonsense mutation in the protocadherin 15 (Pcdh15) gene.
    Naoi K; Kuramoto T; Kuwamura Y; Gohma H; Kuwamura M; Serikawa T
    Exp Anim; 2009 Jan; 58(1):1-10. PubMed ID: 19151506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells.
    Adato A; Lefèvre G; Delprat B; Michel V; Michalski N; Chardenoux S; Weil D; El-Amraoui A; Petit C
    Hum Mol Genet; 2005 Dec; 14(24):3921-32. PubMed ID: 16301217
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23.
    Ahmed ZM; Riazuddin S; Ahmad J; Bernstein SL; Guo Y; Sabar MF; Sieving P; Riazuddin S; Griffith AJ; Friedman TB; Belyantseva IA; Wilcox ER
    Hum Mol Genet; 2003 Dec; 12(24):3215-23. PubMed ID: 14570705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of vestibular dysfunction in the mouse model for Usher syndrome 1F.
    Alagramam KN; Stahl JS; Jones SM; Pawlowski KS; Wright CG
    J Assoc Res Otolaryngol; 2005 Jun; 6(2):106-18. PubMed ID: 15952048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.