BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 37110810)

  • 21. The role of orexin in Alzheimer disease: From sleep-wake disturbance to therapeutic target.
    Gao F; Liu T; Tuo M; Chi S
    Neurosci Lett; 2021 Nov; 765():136247. PubMed ID: 34530113
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The Quest for the Best Dual Orexin Receptor Antagonist (Daridorexant) for the Treatment of Insomnia Disorders.
    Boss C; Gatfield J; Brotschi C; Heidmann B; Sifferlen T; von Raumer M; Schmidt G; Williams JT; Treiber A; Roch C
    ChemMedChem; 2020 Dec; 15(23):2286-2305. PubMed ID: 32937014
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The Insomnia-Addiction Positive Feedback Loop: Role of the Orexin System.
    Fragale JE; James MH; Avila JA; Spaeth AM; Aurora RN; Langleben D; Aston-Jones G
    Front Neurol Neurosci; 2021; 45():117-127. PubMed ID: 34052815
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structure-based development of a subtype-selective orexin 1 receptor antagonist.
    Hellmann J; Drabek M; Yin J; Gunera J; Pröll T; Kraus F; Langmead CJ; Hübner H; Weikert D; Kolb P; Rosenbaum DM; Gmeiner P
    Proc Natl Acad Sci U S A; 2020 Jul; 117(30):18059-18067. PubMed ID: 32669442
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia.
    Coleman PJ; Gotter AL; Herring WJ; Winrow CJ; Renger JJ
    Annu Rev Pharmacol Toxicol; 2017 Jan; 57():509-533. PubMed ID: 27860547
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery and development of orexin receptor antagonists as therapeutics for insomnia.
    Winrow CJ; Renger JJ
    Br J Pharmacol; 2014 Jan; 171(2):283-93. PubMed ID: 23731216
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder.
    Recourt K; de Boer P; Zuiker R; Luthringer R; Kent J; van der Ark P; Van Hove I; van Gerven J; Jacobs G; van Nueten L; Drevets W
    Transl Psychiatry; 2019 Sep; 9(1):216. PubMed ID: 31481683
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Orexin research: patent news from 2016.
    Boss C; Roch C
    Expert Opin Ther Pat; 2017 Oct; 27(10):1123-1133. PubMed ID: 28631980
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Orexin A in adolescents with anxiety disorders.
    Akça ÖF; Uzun N; Kılınç İ
    Int J Psychiatry Clin Pract; 2020 Jun; 24(2):127-134. PubMed ID: 31913740
    [No Abstract]   [Full Text] [Related]  

  • 30. Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and depression.
    Staton CD; Yaeger JDW; Khalid D; Haroun F; Fernandez BS; Fernandez JS; Summers BK; Summers TR; Sathyanesan M; Newton SS; Summers CH
    Neuropharmacology; 2018 Dec; 143():79-94. PubMed ID: 30240784
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia.
    Futamura A; Suzuki R; Tamura Y; Kawamoto H; Ohmichi M; Hino N; Tokumaru Y; Kirinuki S; Hiyoshi T; Aoki T; Kambe D; Nozawa D
    Bioorg Med Chem; 2020 Jul; 28(13):115489. PubMed ID: 32482533
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Hypocretin/Orexin Receptor Pharmacology and Sleep Phases.
    Sun Y; Tisdale RK; Kilduff TS
    Front Neurol Neurosci; 2021; 45():22-37. PubMed ID: 34052813
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model.
    Federici LM; Caliman IF; Molosh AI; Fitz SD; Truitt WA; Bonaventure P; Carpenter JS; Shekhar A; Johnson PL
    Psychoneuroendocrinology; 2016 Mar; 65():127-37. PubMed ID: 26765933
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Efficacy and Safety of Seltorexant as Adjunctive Therapy in Major Depressive Disorder: A Phase 2b, Randomized, Placebo-Controlled, Adaptive Dose-Finding Study.
    Savitz A; Wajs E; Zhang Y; Xu H; Etropolski M; Thase ME; Drevets WC
    Int J Neuropsychopharmacol; 2021 Dec; 24(12):965-976. PubMed ID: 34324636
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanism of action of suvorexant.
    Stahl SM
    CNS Spectr; 2016 Jun; 21(3):215-8. PubMed ID: 27322687
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Orexinergic modulation of serotonin neurons in the dorsal raphe of a diurnal rodent, Arvicanthis niloticus.
    Adidharma W; Deats SP; Ikeno T; Lipton JW; Lonstein JS; Yan L
    Horm Behav; 2019 Nov; 116():104584. PubMed ID: 31445011
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SB-334867, an orexin receptor 1 antagonist, decreased seizure and anxiety in pentylenetetrazol-kindled rats.
    Kordi Jaz E; Moghimi A; Fereidoni M; Asadi S; Shamsizadeh A; Roohbakhsh A
    Fundam Clin Pharmacol; 2017 Apr; 31(2):201-207. PubMed ID: 27739093
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of novel substituted octahydropyrrolo[3,4-c]pyrroles as dual orexin receptor antagonists for insomnia treatment.
    Wu S; Sun Y; Hu Y; Zhang H; Hou L; Liu X; Li Y; He H; Luo Z; Chen Y; Wang Y; Shi W; Shen L; Cao C; Liang W; Xu Q; Lv Q; Lan J; Li J; Chen S
    Bioorg Med Chem Lett; 2017 Mar; 27(6):1458-1462. PubMed ID: 28216404
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Intra-accumbal orexin-1 receptor inhibition prevents the anxiolytic-like effect of ethanol and leads to increases in orexin-A content and receptor expression.
    Morales-Mulia M
    Pharmacol Biochem Behav; 2019 Oct; 185():172761. PubMed ID: 31425712
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Substituted cyclopentanes, tetrahydrofurans and pyrrolidines as orexin-1-receptor antagonists for treatment of various CNS disorders (WO2015/055994; WO2015/124932; WO2015/124934).
    Boss C; Roch C
    Expert Opin Ther Pat; 2016; 26(3):409-15. PubMed ID: 26593218
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.