237 related articles for article (PubMed ID: 37115931)
1. Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy.
Chen YJ; Li GN; Li XJ; Wei LX; Fu MJ; Cheng ZL; Yang Z; Zhu GQ; Wang XD; Zhang C; Zhang JY; Sun YP; Saiyin H; Zhang J; Liu WR; Zhu WW; Guan KL; Xiong Y; Yang Y; Ye D; Chen LL
Sci Adv; 2023 Apr; 9(17):eadg0654. PubMed ID: 37115931
[TBL] [Abstract][Full Text] [Related]
2. Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.
Chen LL; Morcelle C; Cheng ZL; Chen X; Xu Y; Gao Y; Song J; Li Z; Smith MD; Shi M; Zhu Y; Zhou N; Cheng M; He C; Liu KY; Lu G; Zhang L; Zhang C; Zhang J; Sun Y; Qi T; Lyu Y; Ren ZZ; Tan XM; Yin J; Lan F; Liu Y; Yang H; Qian M; Duan C; Chang X; Zhou Y; Shen L; Baldwin AS; Guan KL; Xiong Y; Ye D
Nat Cell Biol; 2022 Mar; 24(3):353-363. PubMed ID: 35256775
[TBL] [Abstract][Full Text] [Related]
3. Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Michelucci A; Cordes T; Ghelfi J; Pailot A; Reiling N; Goldmann O; Binz T; Wegner A; Tallam A; Rausell A; Buttini M; Linster CL; Medina E; Balling R; Hiller K
Proc Natl Acad Sci U S A; 2013 May; 110(19):7820-5. PubMed ID: 23610393
[TBL] [Abstract][Full Text] [Related]
4. Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides.
Schofield JH; Longo J; Sheldon RD; Albano E; Ellis AE; Hawk MA; Murphy S; Duong L; Rahmy S; Lu X; Jones RG; Schafer ZT
Cell Rep; 2024 Apr; 43(4):113984. PubMed ID: 38520689
[TBL] [Abstract][Full Text] [Related]
5. Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages.
Tallam A; Perumal TM; Antony PM; Jäger C; Fritz JV; Vallar L; Balling R; Del Sol A; Michelucci A
PLoS One; 2016; 11(2):e0149050. PubMed ID: 26872335
[TBL] [Abstract][Full Text] [Related]
6. Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency.
Pires-Afonso Y; Muller A; Grzyb K; Oudin A; Yabo YA; Sousa C; Scafidi A; Poli A; Cosma A; Halder R; Coowar D; Golebiewska A; Skupin A; Niclou SP; Michelucci A
Mol Oncol; 2022 Sep; 16(17):3167-3191. PubMed ID: 35838338
[TBL] [Abstract][Full Text] [Related]
7. Targeted macrophage phagocytosis by Irg1/itaconate axis improves the prognosis of intracerebral hemorrhagic stroke and peritonitis.
Luo Z; Sheng Z; Hu L; Shi L; Tian Y; Zhao X; Yang W; Xiao Z; Shen D; Wu W; Lan T; Zhao B; Wang X; Zhuang N; Zhang JN; Wang Y; Lu Y; Wang L; Zhang C; Wang P; An J; Yang F; Li Q
EBioMedicine; 2024 Mar; 101():104993. PubMed ID: 38324982
[TBL] [Abstract][Full Text] [Related]
8. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.
Weiss JM; Davies LC; Karwan M; Ileva L; Ozaki MK; Cheng RY; Ridnour LA; Annunziata CM; Wink DA; McVicar DW
J Clin Invest; 2018 Aug; 128(9):3794-3805. PubMed ID: 29920191
[TBL] [Abstract][Full Text] [Related]
9. Mycobacterium paratuberculosis, Mycobacterium smegmatis, and lipopolysaccharide induce different transcriptional and post-transcriptional regulation of the IRG1 gene in murine macrophages.
Basler T; Jeckstadt S; Valentin-Weigand P; Goethe R
J Leukoc Biol; 2006 Mar; 79(3):628-38. PubMed ID: 16415166
[TBL] [Abstract][Full Text] [Related]
10. Deficiency of IRG1/ itaconate aggravates endotoxemia-induced acute lung injury by inhibiting autophagy in mice.
Qiu JH; Zhang L; Li KX; Zhang QH; Fan KR; Chen K; Jiang Y; Liu G
Exp Anim; 2023 May; 72(2):164-172. PubMed ID: 36288955
[TBL] [Abstract][Full Text] [Related]
11. USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer.
Dai X; Lu L; Deng S; Meng J; Wan C; Huang J; Sun Y; Hu Y; Wu B; Wu G; Lovell JF; Jin H; Yang K
Theranostics; 2020; 10(20):9332-9347. PubMed ID: 32802195
[No Abstract] [Full Text] [Related]
12. IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila.
Price JV; Russo D; Ji DX; Chavez RA; DiPeso L; Lee AY; Coers J; Vance RE
mBio; 2019 Nov; 10(6):. PubMed ID: 31719183
[TBL] [Abstract][Full Text] [Related]
13. TNF and type I IFN induction of the IRG1-itaconate pathway restricts
Boyer MA; Fischer NL; Shin S
bioRxiv; 2023 Jul; ():. PubMed ID: 37461589
[TBL] [Abstract][Full Text] [Related]
14. Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8
Fang W; Zhou T; Shi H; Yao M; Zhang D; Qian H; Zeng Q; Wang Y; Jin F; Chai C; Chen T
J Exp Clin Cancer Res; 2021 Jan; 40(1):4. PubMed ID: 33390170
[TBL] [Abstract][Full Text] [Related]
15. Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever.
Kohl L; Siddique MNAA; Bodendorfer B; Berger R; Preikschat A; Daniel C; Ölke M; Liebler-Tenorio E; Schulze-Luehrmann J; Mauermeir M; Yang KT; Hayek I; Szperlinski M; Andrack J; Schleicher U; Bozec A; Krönke G; Murray PJ; Wirtz S; Yamamoto M; Schatz V; Jantsch J; Oefner P; Degrandi D; Pfeffer K; Mertens-Scholz K; Rauber S; Bogdan C; Dettmer K; Lührmann A; Lang R
EMBO Mol Med; 2023 Feb; 15(2):e15931. PubMed ID: 36479617
[TBL] [Abstract][Full Text] [Related]
16. Cepharanthine Alleviates DSS-Induced Ulcerative Colitis via Regulating Aconitate Decarboxylase 1 Expression and Macrophage Infiltration.
Zhang MN; Xie R; Wang HG; Wen X; Wang JY; He L; Zhang MH; Yang XZ
Molecules; 2023 Jan; 28(3):. PubMed ID: 36770726
[TBL] [Abstract][Full Text] [Related]
17. CXCL9-expressing tumor-associated macrophages: new players in the fight against cancer.
Marcovecchio PM; Thomas G; Salek-Ardakani S
J Immunother Cancer; 2021 Feb; 9(2):. PubMed ID: 33637602
[TBL] [Abstract][Full Text] [Related]
18. Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species.
Li Y; Zhang P; Wang C; Han C; Meng J; Liu X; Xu S; Li N; Wang Q; Shi X; Cao X
J Biol Chem; 2013 Jun; 288(23):16225-16234. PubMed ID: 23609450
[TBL] [Abstract][Full Text] [Related]
19. Suppression of IRG-1 Reduces Inflammatory Cell Infiltration and Lung Injury in Respiratory Syncytial Virus Infection by Reducing Production of Reactive Oxygen Species.
Ren K; Lv Y; Zhuo Y; Chen C; Shi H; Guo L; Yang G; Hou Y; Tan RX; Li E
J Virol; 2016 Aug; 90(16):7313-7322. PubMed ID: 27252532
[TBL] [Abstract][Full Text] [Related]
20. Total glucosides of paeony inhibit breast cancer growth by inhibiting TAMs infiltration through NF-κB/CCL2 signaling.
Jin L; Guo Y; Mao W; Wang J; Jin L; Liu X; Shou Q; Fu H
Phytomedicine; 2022 Sep; 104():154307. PubMed ID: 35841664
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
