BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 37130459)

  • 1. ALS-causing hPFN1 mutants differentially disrupt LLPS of FUS prion-like domain.
    Kang J; Lim L; Song J
    Biochem Biophys Res Commun; 2023 Jul; 664():35-42. PubMed ID: 37130459
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanisms of phase separation and amyloidosis of ALS/FTD-linked FUS and TDP-43.
    Song J
    Aging Dis; 2023 Nov; ():. PubMed ID: 38029395
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids.
    Kang J; Lim L; Lu Y; Song J
    PLoS Biol; 2019 Jun; 17(6):e3000327. PubMed ID: 31188823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATP enhances at low concentrations but dissolves at high concentrations liquid-liquid phase separation (LLPS) of ALS/FTD-causing FUS.
    Kang J; Lim L; Song J
    Biochem Biophys Res Commun; 2018 Oct; 504(2):545-551. PubMed ID: 30205960
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
    Patel A; Lee HO; Jawerth L; Maharana S; Jahnel M; Hein MY; Stoynov S; Mahamid J; Saha S; Franzmann TM; Pozniakovski A; Poser I; Maghelli N; Royer LA; Weigert M; Myers EW; Grill S; Drechsel D; Hyman AA; Alberti S
    Cell; 2015 Aug; 162(5):1066-77. PubMed ID: 26317470
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATP induces folding of ALS-causing C71G-hPFN1 and nascent hSOD1.
    Kang J; Lim L; Song J
    Commun Chem; 2023 Sep; 6(1):186. PubMed ID: 37670116
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism underlying liquid-to-solid phase transition in fused in sarcoma liquid droplets.
    Li S; Yoshizawa T; Shiramasa Y; Kanamaru M; Ide F; Kitamura K; Kashiwagi N; Sasahara N; Kitazawa S; Kitahara R
    Phys Chem Chem Phys; 2022 Aug; 24(32):19346-19353. PubMed ID: 35943083
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS.
    Rhoads SN; Monahan ZT; Yee DS; Shewmaker FP
    Int J Mol Sci; 2018 Mar; 19(3):. PubMed ID: 29547565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
    Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
    Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ALS-causing profilin-1-mutant forms a non-native helical structure in membrane environments.
    Lim L; Kang J; Song J
    Biochim Biophys Acta Biomembr; 2017 Nov; 1859(11):2161-2170. PubMed ID: 28847504
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A dynamic regulatory switch for phase separation of FUS protein: Zinc ions and zinc finger domain.
    Chen Y; Pei X; Chen L; Chen L
    Biochem Biophys Res Commun; 2024 May; 710():149862. PubMed ID: 38593618
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Implications of the prion-related Q/N domains in TDP-43 and FUS.
    Udan M; Baloh RH
    Prion; 2011; 5(1):1-5. PubMed ID: 21135580
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ALS-linked FUS mutations dysregulate G-quadruplex-dependent liquid-liquid phase separation and liquid-to-solid transition.
    Ishiguro A; Lu J; Ozawa D; Nagai Y; Ishihama A
    J Biol Chem; 2021 Nov; 297(5):101284. PubMed ID: 34624313
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid-solid phase transition.
    Shiramasa Y; Yamamoto R; Kashiwagi N; Sasaki F; Imai S; Ike M; Kitazawa S; Kameda T; Kitahara R
    Sci Rep; 2024 Apr; 14(1):8914. PubMed ID: 38632300
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
    Finelli MJ; Liu KX; Wu Y; Oliver PL; Davies KE
    Hum Mol Genet; 2015 Jun; 24(12):3529-44. PubMed ID: 25792726
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.
    Lim L; Wei Y; Lu Y; Song J
    PLoS Biol; 2016 Jan; 14(1):e1002338. PubMed ID: 26735904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FUS fibrillation occurs through a nucleation-based process below the critical concentration required for liquid-liquid phase separation.
    Bertrand E; Demongin C; Dobra I; Rengifo-Gonzalez JC; Singatulina AS; Sukhanova MV; Lavrik OI; Pastré D; Hamon L
    Sci Rep; 2023 May; 13(1):7772. PubMed ID: 37179431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.
    Ito D; Suzuki N
    Neurology; 2011 Oct; 77(17):1636-43. PubMed ID: 21956718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
    Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
    Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein aggregates and regional disease spread in ALS is reminiscent of prion-like pathogenesis.
    Verma A
    Neurol India; 2013; 61(2):107-10. PubMed ID: 23644307
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.