175 related articles for article (PubMed ID: 37131962)
1. Targeting the vital non-structural proteins (NSP12, NSP7, NSP8 and NSP3) from SARS-CoV-2 and inhibition of RNA polymerase by natural bioactive compound naringenin as a promising drug candidate against COVID-19.
Aleebrahim-Dehkordi E; Ghoshouni H; Koochaki P; Esmaili-Dehkordi M; Aleebrahim E; Chichagi F; Jafari A; Hanaei S; Heidari-Soureshjani E; Rezaei N
J Mol Struct; 2023 Sep; 1287():135642. PubMed ID: 37131962
[TBL] [Abstract][Full Text] [Related]
2. Comparison of Binding Site of Remdesivir and Its Metabolites with NSP12-NSP7-NSP8, and NSP3 of SARS CoV-2 Virus and Alternative Potential Drugs for COVID-19 Treatment.
Jung LS; Gund TM; Narayan M
Protein J; 2020 Dec; 39(6):619-630. PubMed ID: 33185784
[TBL] [Abstract][Full Text] [Related]
3. Molecular modelling and structure-activity relationship of a natural derivative of
Ayipo YO; Ahmad I; Najib YS; Sheu SK; Patel H; Mordi MN
J Biomol Struct Dyn; 2023 Mar; 41(5):1959-1977. PubMed ID: 35037841
[TBL] [Abstract][Full Text] [Related]
4. SARS-CoV-2 and SARS-CoV: Virtual screening of potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12).
Ruan Z; Liu C; Guo Y; He Z; Huang X; Jia X; Yang T
J Med Virol; 2021 Jan; 93(1):389-400. PubMed ID: 32579254
[TBL] [Abstract][Full Text] [Related]
5. Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resistance to remdesivir.
Martin R; Li J; Parvangada A; Perry J; Cihlar T; Mo H; Porter D; Svarovskaia E
Antiviral Res; 2021 Apr; 188():105033. PubMed ID: 33549572
[TBL] [Abstract][Full Text] [Related]
6. Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an
Mutlu O; Ugurel OM; Sariyer E; Ata O; Inci TG; Ugurel E; Kocer S; Turgut-Balik D
J Biomol Struct Dyn; 2022 Feb; 40(2):918-930. PubMed ID: 32933378
[TBL] [Abstract][Full Text] [Related]
7. Multi-targeting approach for nsp3, nsp9, nsp12 and nsp15 proteins of SARS-CoV-2 by Diosmin as illustrated by molecular docking and molecular dynamics simulation methodologies.
Kumar S; Sharma PP; Upadhyay C; Kempaiah P; Rathi B; Poonam
Methods; 2021 Nov; 195():44-56. PubMed ID: 33639316
[TBL] [Abstract][Full Text] [Related]
8. Peptide inhibitors derived from the nsp7 and nsp8 cofactors of nsp12 targeting different substrate binding sites of nsp12 of the SARS-CoV-2.
Jena NR; Pant S
J Biomol Struct Dyn; 2023 Jul; ():1-13. PubMed ID: 37434315
[TBL] [Abstract][Full Text] [Related]
9. Transient SARS-CoV-2 RNA-Dependent RNA Polymerase Mutations after Remdesivir Treatment for Chronic COVID-19 in Two Transplant Recipients: Case Report and Intra-Host Viral Genomic Investigation.
Yang S; Multani A; Garrigues JM; Oh MS; Hemarajata P; Burleson T; Green NM; Oliai C; Gaynor PT; Beaird OE; Winston DJ; Seet CS; Schaenman JM
Microorganisms; 2023 Aug; 11(8):. PubMed ID: 37630656
[TBL] [Abstract][Full Text] [Related]
10. Potential inhibitors of SARS-cov-2 RNA dependent RNA polymerase protein: molecular docking, molecular dynamics simulations and MM-PBSA analyses.
Elkarhat Z; Charoute H; Elkhattabi L; Barakat A; Rouba H
J Biomol Struct Dyn; 2022 Jan; 40(1):361-374. PubMed ID: 32873176
[TBL] [Abstract][Full Text] [Related]
11. The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
Gordon CJ; Tchesnokov EP; Feng JY; Porter DP; Götte M
J Biol Chem; 2020 Apr; 295(15):4773-4779. PubMed ID: 32094225
[TBL] [Abstract][Full Text] [Related]
12. Plant-Derived Natural Non-Nucleoside Analog Inhibitors (NNAIs) against
Naidu SAG; Mustafa G; Clemens RA; Naidu AS
J Diet Suppl; 2023; 20(2):254-283. PubMed ID: 34850656
[TBL] [Abstract][Full Text] [Related]
13. Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants.
Pitts J; Li J; Perry JK; Du Pont V; Riola N; Rodriguez L; Lu X; Kurhade C; Xie X; Camus G; Manhas S; Martin R; Shi PY; Cihlar T; Porter DP; Mo H; Maiorova E; Bilello JP
Antimicrob Agents Chemother; 2022 Jun; 66(6):e0022222. PubMed ID: 35532238
[TBL] [Abstract][Full Text] [Related]
14. Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
Biswal M; Diggs S; Xu D; Khudaverdyan N; Lu J; Fang J; Blaha G; Hai R; Song J
Nucleic Acids Res; 2021 Jun; 49(10):5956-5966. PubMed ID: 33999154
[TBL] [Abstract][Full Text] [Related]
15. Investigation of protein-protein interactions and hotspot region on the NSP7-NSP8 binding site in NSP12 of SARS-CoV-2.
Lima Neto JX; Bezerra KS; Barbosa ED; Araujo RL; Galvão DS; Lyra ML; Oliveira JIN; Akash S; Jardan YAB; Nafidi HA; Bourhia M; Fulco UL
Front Mol Biosci; 2023; 10():1325588. PubMed ID: 38304231
[No Abstract] [Full Text] [Related]
16. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Wang Q; Wu J; Wang H; Gao Y; Liu Q; Mu A; Ji W; Yan L; Zhu Y; Zhu C; Fang X; Yang X; Huang Y; Gao H; Liu F; Ge J; Sun Q; Yang X; Xu W; Liu Z; Yang H; Lou Z; Jiang B; Guddat LW; Gong P; Rao Z
Cell; 2020 Jul; 182(2):417-428.e13. PubMed ID: 32526208
[TBL] [Abstract][Full Text] [Related]
17. Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency.
Gordon CJ; Tchesnokov EP; Woolner E; Perry JK; Feng JY; Porter DP; Götte M
J Biol Chem; 2020 May; 295(20):6785-6797. PubMed ID: 32284326
[TBL] [Abstract][Full Text] [Related]
18. In silico studies of selected multi-drug targeting against 3CLpro and nsp12 RNA-dependent RNA-polymerase proteins of SARS-CoV-2 and SARS-CoV.
Udofia IA; Gbayo KO; Oloba-Whenu OA; Ogunbayo TB; Isanbor C
Netw Model Anal Health Inform Bioinform; 2021; 10(1):22. PubMed ID: 33786291
[TBL] [Abstract][Full Text] [Related]
19. Revealing the Inhibition Mechanism of RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Remdesivir and Nucleotide Analogues: A Molecular Dynamics Simulation Study.
Wakchaure PD; Ghosh S; Ganguly B
J Phys Chem B; 2020 Nov; 124(47):10641-10652. PubMed ID: 33190493
[TBL] [Abstract][Full Text] [Related]
20. Genetic Study of SARS-CoV-2 Non Structural Protein 12 in COVID-19 Patients Non Responders to Remdesivir.
Santos Bravo M; Alonso R; Soria D; Sánchez Palomino S; Sanzo Machuca Á; Rodríguez C; Alcamí J; Díez-Fuertes F; Simarro Redon À; Hurtado JC; Fernández Avilés F; Bodro M; Rubio E; Villanueva JL; Vergara A; Castro P; Tuset M; Cuesta G; Puerta P; García C; Mosquera Gutiérrez MDM; Martínez MJ; Vila J; Soriano A; Marcos MÁ
Microbiol Spectr; 2022 Dec; 10(6):e0244822. PubMed ID: 36354320
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
