BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 37132604)

  • 1. NAD(P)H: quinone oxidoreductase 1 activatable toll-like receptor 7/8 agonist designed for precise immunotherapy.
    Li G; Xu Y; Kong X; Gu L; Qin Y; Wu L
    Chem Commun (Camb); 2023 May; 59(42):6343-6346. PubMed ID: 37132604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An NAD(P)H:Quinone Oxidoreductase 1 Responsive and Self-Immolative Prodrug of 5-Fluorouracil for Safe and Effective Cancer Therapy.
    Zhang X; Li X; Li Z; Wu X; Wu Y; You Q; Zhang X
    Org Lett; 2018 Jun; 20(12):3635-3638. PubMed ID: 29847952
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human NAD(P)H:quinone oxidoreductase type I (hNQO1) activation of quinone propionic acid trigger groups.
    Mendoza MF; Hollabaugh NM; Hettiarachchi SU; McCarley RL
    Biochemistry; 2012 Oct; 51(40):8014-26. PubMed ID: 22989153
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NAD(P)H:Quinone Oxidoreductase 1 (NQO1) as a Therapeutic and Diagnostic Target in Cancer.
    Zhang K; Chen D; Ma K; Wu X; Hao H; Jiang S
    J Med Chem; 2018 Aug; 61(16):6983-7003. PubMed ID: 29712428
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemical synthesis and biological evaluation of a NAD(P)H:quinone oxidoreductase-1 targeted tripartite quinone drug delivery system.
    Volpato M; Abou-Zeid N; Tanner RW; Glassbrook LT; Taylor J; Stratford I; Loadman PM; Jaffar M; Phillips RM
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3122-30. PubMed ID: 18089707
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Research advances in NQO1-responsive prodrugs and nanocarriers for cancer treatment.
    Yang X; Duan J; Wu L
    Future Med Chem; 2022 Mar; 14(5):363-383. PubMed ID: 35102756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of NAD(P)H: Quinone oxidoreductase (NQO1)-activated prodrugs of 23-hydroxybetulinic acid with enhanced antitumor properties.
    Zhu H; Lu L; Zhu W; Tan Y; Duan Y; Liu J; Ye W; Zhu Z; Xu J; Xu S
    Eur J Med Chem; 2022 Oct; 240():114575. PubMed ID: 35803175
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NAD(P)H:Quinone Acceptor Oxidoreductase 1 (NQO1) Activatable Salicylamide H
    Roy NJ; Save SN; Sharma VK; Abraham B; Kuttanamkuzhi A; Sharma S; Lahiri M; Talukdar P
    Chemistry; 2023 Sep; 29(51):e202301412. PubMed ID: 37345998
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance.
    Li X; Liu Z; Zhang A; Han C; Shen A; Jiang L; Boothman DA; Qiao J; Wang Y; Huang X; Fu YX
    Nat Commun; 2019 Jul; 10(1):3251. PubMed ID: 31324798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones.
    Siegel D; Yan C; Ross D
    Biochem Pharmacol; 2012 Apr; 83(8):1033-40. PubMed ID: 22209713
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones.
    Winski SL; Swann E; Hargreaves RH; Dehn DL; Butler J; Moody CJ; Ross D
    Biochem Pharmacol; 2001 Jun; 61(12):1509-16. PubMed ID: 11377380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.
    den Braver-Sewradj SP; den Braver MW; Toorneman RM; van Leeuwen S; Zhang Y; Dekker SJ; Vermeulen NPE; Commandeur JNM; Vos JC
    Chem Res Toxicol; 2018 Feb; 31(2):116-126. PubMed ID: 29281794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development of a new isogenic cell-xenograft system for evaluation of NAD(P)H:quinone oxidoreductase-directed antitumor quinones: evaluation of the activity of RH1.
    Dehn DL; Winski SL; Ross D
    Clin Cancer Res; 2004 May; 10(9):3147-55. PubMed ID: 15131056
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.
    Colucci MA; Moody CJ; Couch GD
    Org Biomol Chem; 2008 Feb; 6(4):637-56. PubMed ID: 18264564
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of beta-lapachone prodrugs for therapy against human cancer cells with elevated NAD(P)H:quinone oxidoreductase 1 levels.
    Reinicke KE; Bey EA; Bentle MS; Pink JJ; Ingalls ST; Hoppel CL; Misico RI; Arzac GM; Burton G; Bornmann WG; Sutton D; Gao J; Boothman DA
    Clin Cancer Res; 2005 Apr; 11(8):3055-64. PubMed ID: 15837761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intracellular Enzyme-Responsive Profluorophore and Prodrug Nanoparticles for Tumor-Specific Imaging and Precise Chemotherapy.
    Pei Q; Lu S; Zhou J; Jiang B; Li C; Xie Z; Jing X
    ACS Appl Mater Interfaces; 2021 Dec; 13(50):59708-59719. PubMed ID: 34879654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of NQO1-activated prodrugs of podophyllotoxin as antitumor agents.
    Qu Y; Zhang C; Ma X; Gao Y; Liu J; Wu L
    Bioorg Med Chem; 2020 Dec; 28(24):115821. PubMed ID: 33091789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.
    Huang X; Dong Y; Bey EA; Kilgore JA; Bair JS; Li LS; Patel M; Parkinson EI; Wang Y; Williams NS; Gao J; Hergenrother PJ; Boothman DA
    Cancer Res; 2012 Jun; 72(12):3038-47. PubMed ID: 22532167
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors.
    Han Y; Shen H; Carr BI; Wipf P; Lazo JS; Pan SS
    J Pharmacol Exp Ther; 2004 Apr; 309(1):64-70. PubMed ID: 14718602
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Indolequinone antitumor agents: correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity.
    Beall HD; Winski S; Swann E; Hudnott AR; Cotterill AS; O'Sullivan N; Green SJ; Bien R; Siegel D; Ross D; Moody CJ
    J Med Chem; 1998 Nov; 41(24):4755-66. PubMed ID: 9822546
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.