BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

347 related articles for article (PubMed ID: 37138318)

  • 1. The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson's disease.
    Lau HHC; Martinez-Valbuena I; So RWL; Mehra S; Silver NRG; Mao A; Stuart E; Schmitt-Ulms C; Hyman BT; Ingelsson M; Kovacs GG; Watts JC
    Acta Neuropathol Commun; 2023 May; 11(1):72. PubMed ID: 37138318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation.
    Kiely AP; Ling H; Asi YT; Kara E; Proukakis C; Schapira AH; Morris HR; Roberts HC; Lubbe S; Limousin P; Lewis PA; Lees AJ; Quinn N; Hardy J; Love S; Revesz T; Houlden H; Holton JL
    Mol Neurodegener; 2015 Aug; 10():41. PubMed ID: 26306801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.
    Woerman AL; Oehler A; Kazmi SA; Lee J; Halliday GM; Middleton LT; Gentleman SM; Mordes DA; Spina S; Grinberg LT; Olson SH; Prusiner SB
    Acta Neuropathol; 2019 Mar; 137(3):437-454. PubMed ID: 30690664
    [TBL] [Abstract][Full Text] [Related]  

  • 4. α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?
    Kiely AP; Asi YT; Kara E; Limousin P; Ling H; Lewis P; Proukakis C; Quinn N; Lees AJ; Hardy J; Revesz T; Houlden H; Holton JL
    Acta Neuropathol; 2013 May; 125(5):753-69. PubMed ID: 23404372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetics of Synucleinopathies.
    Nussbaum RL
    Cold Spring Harb Perspect Med; 2018 Jun; 8(6):. PubMed ID: 28213435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.
    Fares MB; Ait-Bouziad N; Dikiy I; Mbefo MK; Jovičić A; Kiely A; Holton JL; Lee SJ; Gitler AD; Eliezer D; Lashuel HA
    Hum Mol Genet; 2014 Sep; 23(17):4491-509. PubMed ID: 24728187
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein.
    Rutherford NJ; Moore BD; Golde TE; Giasson BI
    J Neurochem; 2014 Dec; 131(6):859-67. PubMed ID: 24984882
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
    Ferreira N; Gram H; Sorrentino ZA; Gregersen E; Schmidt SI; Reimer L; Betzer C; Perez-Gozalbo C; Beltoja M; Nagaraj M; Wang J; Nowak JS; Dong M; Willén K; Cholak E; Bjerregaard-Andersen K; Mendez N; Rabadia P; Shahnawaz M; Soto C; Otzen DE; Akbey Ü; Meyer M; Giasson BI; Romero-Ramos M; Jensen PH
    Acta Neuropathol; 2021 Jul; 142(1):87-115. PubMed ID: 33978813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics.
    Yamasaki TR; Holmes BB; Furman JL; Dhavale DD; Su BW; Song ES; Cairns NJ; Kotzbauer PT; Diamond MI
    J Biol Chem; 2019 Jan; 294(3):1045-1058. PubMed ID: 30478174
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice.
    Lavenir I; Passarella D; Masuda-Suzukake M; Curry A; Holton JL; Ghetti B; Goedert M
    Acta Neuropathol Commun; 2019 Sep; 7(1):148. PubMed ID: 31522685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation of TWO G51D SNCA missense mutation iPSC lines (CRICKi011-A, CRICKi012-A) from two individuals at risk of Parkinson's disease.
    Devito LG; Zanjani ZS; Evans JR; Scardamaglia A; Houlden H; Gandhi S; Healy L
    Stem Cell Res; 2023 Sep; 71():103134. PubMed ID: 37336145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein.
    Holec SAM; Lee J; Oehler A; Ooi FK; Mordes DA; Olson SH; Prusiner SB; Woerman AL
    Acta Neuropathol; 2022 Oct; 144(4):677-690. PubMed ID: 36018376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing.
    Perez-Rodriguez D; Kalyva M; Leija-Salazar M; Lashley T; Tarabichi M; Chelban V; Gentleman S; Schottlaender L; Franklin H; Vasmatzis G; Houlden H; Schapira AHV; Warner TT; Holton JL; Jaunmuktane Z; Proukakis C
    Acta Neuropathol Commun; 2019 Dec; 7(1):219. PubMed ID: 31870437
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies.
    Van der Perren A; Gelders G; Fenyi A; Bousset L; Brito F; Peelaerts W; Van den Haute C; Gentleman S; Melki R; Baekelandt V
    Acta Neuropathol; 2020 Jun; 139(6):977-1000. PubMed ID: 32356200
    [TBL] [Abstract][Full Text] [Related]  

  • 15. α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species.
    Morgan SA; Lavenir I; Fan J; Masuda-Suzukake M; Passarella D; DeTure MA; Dickson DW; Ghetti B; Goedert M
    J Biol Chem; 2020 May; 295(19):6652-6664. PubMed ID: 32209651
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.
    Bernis ME; Babila JT; Breid S; Wüsten KA; Wüllner U; Tamgüney G
    Acta Neuropathol Commun; 2015 Nov; 3():75. PubMed ID: 26612754
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physicochemical characterization of the G51D mutation of α-synuclein that is responsible for its severe cytotoxicity.
    Murata T; Tochio N; Utsunomiya-Tate N
    Neurosci Lett; 2021 Aug; 760():136077. PubMed ID: 34161822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lysosomal response in relation to α-synuclein pathology differs between Parkinson's disease and multiple system atrophy.
    Puska G; Lutz MI; Molnar K; Regelsberger G; Ricken G; Pirker W; Laszlo L; Kovacs GG
    Neurobiol Dis; 2018 Jun; 114():140-152. PubMed ID: 29505813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structurally distinct α-synuclein fibrils induce robust parkinsonian pathology.
    Hayakawa H; Nakatani R; Ikenaka K; Aguirre C; Choong CJ; Tsuda H; Nagano S; Koike M; Ikeuchi T; Hasegawa M; Papa SM; Nagai Y; Mochizuki H; Baba K
    Mov Disord; 2020 Feb; 35(2):256-267. PubMed ID: 31643109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.
    Prusiner SB; Woerman AL; Mordes DA; Watts JC; Rampersaud R; Berry DB; Patel S; Oehler A; Lowe JK; Kravitz SN; Geschwind DH; Glidden DV; Halliday GM; Middleton LT; Gentleman SM; Grinberg LT; Giles K
    Proc Natl Acad Sci U S A; 2015 Sep; 112(38):E5308-17. PubMed ID: 26324905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.