BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 37156396)

  • 21. Reconstitution and characterization of the polynuclear iron-sulfur cluster in pyruvate formate-lyase-activating enzyme. Molecular properties of the holoenzyme form.
    Külzer R; Pils T; Kappl R; Hüttermann J; Knappe J
    J Biol Chem; 1998 Feb; 273(9):4897-903. PubMed ID: 9478932
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.
    Byer AS; Yang H; McDaniel EC; Kathiresan V; Impano S; Pagnier A; Watts H; Denler C; Vagstad AL; Piel J; Duschene KS; Shepard EM; Shields TP; Scott LG; Lilla EA; Yokoyama K; Broderick WE; Hoffman BM; Broderick JB
    J Am Chem Soc; 2018 Jul; 140(28):8634-8638. PubMed ID: 29954180
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pyruvate formate-lyase activating enzyme: elucidation of a novel mechanism for glycyl radical formation.
    Buis JM; Broderick JB
    Arch Biochem Biophys; 2005 Jan; 433(1):288-96. PubMed ID: 15581584
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Pyruvate formate-lyase-activating enzyme: strictly anaerobic isolation yields active enzyme containing a [3Fe-4S](+) cluster.
    Broderick JB; Henshaw TF; Cheek J; Wojtuszewski K; Smith SR; Trojan MR; McGhan RM; Kopf A; Kibbey M; Broderick WE
    Biochem Biophys Res Commun; 2000 Mar; 269(2):451-6. PubMed ID: 10708574
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Auxiliary iron-sulfur cofactors in radical SAM enzymes.
    Lanz ND; Booker SJ
    Biochim Biophys Acta; 2015 Jun; 1853(6):1316-34. PubMed ID: 25597998
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Binding energy in the one-electron reductive cleavage of S-adenosylmethionine in lysine 2,3-aminomutase, a radical SAM enzyme.
    Wang SC; Frey PA
    Biochemistry; 2007 Nov; 46(45):12889-95. PubMed ID: 17944492
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Active-Site Controlled, Jahn-Teller Enabled Regioselectivity in Reductive S-C Bond Cleavage of
    Impano S; Yang H; Jodts RJ; Pagnier A; Swimley R; McDaniel EC; Shepard EM; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2021 Jan; 143(1):335-348. PubMed ID: 33372786
    [TBL] [Abstract][Full Text] [Related]  

  • 28. [2Fe-2S] to [4Fe-4S] cluster conversion in Escherichia coli biotin synthase.
    Duin EC; Lafferty ME; Crouse BR; Allen RM; Sanyal I; Flint DH; Johnson MK
    Biochemistry; 1997 Sep; 36(39):11811-20. PubMed ID: 9305972
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Spectroscopic, steady-state kinetic, and mechanistic characterization of the radical SAM enzyme QueE, which catalyzes a complex cyclization reaction in the biosynthesis of 7-deazapurines.
    McCarty RM; Krebs C; Bandarian V
    Biochemistry; 2013 Jan; 52(1):188-98. PubMed ID: 23194065
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Paramagnetic intermediates generated by radical S-adenosylmethionine (SAM) enzymes.
    Stich TA; Myers WK; Britt RD
    Acc Chem Res; 2014 Aug; 47(8):2235-43. PubMed ID: 24991701
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
    Dong M; Horitani M; Dzikovski B; Freed JH; Ealick SE; Hoffman BM; Lin H
    J Am Chem Soc; 2017 Apr; 139(16):5680-5683. PubMed ID: 28383907
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Spectroscopic approaches to elucidating novel iron-sulfur chemistry in the "radical-Sam" protein superfamily.
    Walsby CJ; Ortillo D; Yang J; Nnyepi MR; Broderick WE; Hoffman BM; Broderick JB
    Inorg Chem; 2005 Feb; 44(4):727-41. PubMed ID: 15859242
    [TBL] [Abstract][Full Text] [Related]  

  • 33. In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters.
    Grove TL; Lee KH; St Clair J; Krebs C; Booker SJ
    Biochemistry; 2008 Jul; 47(28):7523-38. PubMed ID: 18558715
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.
    Horitani M; Shisler K; Broderick WE; Hutcheson RU; Duschene KS; Marts AR; Hoffman BM; Broderick JB
    Science; 2016 May; 352(6287):822-5. PubMed ID: 27174986
    [TBL] [Abstract][Full Text] [Related]  

  • 35. S-Adenosylmethionine-dependent reduction of lysine 2,3-aminomutase and observation of the catalytically functional iron-sulfur centers by electron paramagnetic resonance.
    Lieder KW; Booker S; Ruzicka FJ; Beinert H; Reed GH; Frey PA
    Biochemistry; 1998 Feb; 37(8):2578-85. PubMed ID: 9485408
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Radical S-Adenosyl-L-methionine Enzyme QhpD Catalyzes Sequential Formation of Intra-protein Sulfur-to-Methylene Carbon Thioether Bonds.
    Nakai T; Ito H; Kobayashi K; Takahashi Y; Hori H; Tsubaki M; Tanizawa K; Okajima T
    J Biol Chem; 2015 Apr; 290(17):11144-66. PubMed ID: 25778402
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Trapping and Electron Paramagnetic Resonance Characterization of the 5'dAdo
    Sayler RI; Stich TA; Joshi S; Cooper N; Shaw JT; Begley TP; Tantillo DJ; Britt RD
    ACS Cent Sci; 2019 Nov; 5(11):1777-1785. PubMed ID: 31807679
    [No Abstract]   [Full Text] [Related]  

  • 38. Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy.
    Yokoyama K; Ohmori D; Kudo F; Eguchi T
    Biochemistry; 2008 Aug; 47(34):8950-60. PubMed ID: 18672902
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA.
    Pang H; Walker LM; Silakov A; Zhang P; Yang W; Elliott SJ; Yokoyama K
    J Am Chem Soc; 2021 Sep; 143(34):13835-13844. PubMed ID: 34423974
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site.
    Frey M; Rothe M; Wagner AF; Knappe J
    J Biol Chem; 1994 Apr; 269(17):12432-7. PubMed ID: 8175649
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.