180 related articles for article (PubMed ID: 37175873)
1.
Galeana-Ascencio RA; Mendieta L; Limon DI; Gnecco D; Terán JL; Orea ML; Carrasco-Carballo A
Int J Mol Sci; 2023 May; 24(9):. PubMed ID: 37175873
[TBL] [Abstract][Full Text] [Related]
2. Flavonols and flavones as BACE-1 inhibitors: structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features.
Shimmyo Y; Kihara T; Akaike A; Niidome T; Sugimoto H
Biochim Biophys Acta; 2008 May; 1780(5):819-25. PubMed ID: 18295609
[TBL] [Abstract][Full Text] [Related]
3. Guanidine-based β amyloid precursor protein cleavage enzyme 1 (BACE-1) inhibitors for the Alzheimer's disease (AD): A review.
Gehlot P; Kumar S; Kumar Vyas V; Singh Choudhary B; Sharma M; Malik R
Bioorg Med Chem; 2022 Nov; 74():117047. PubMed ID: 36265268
[TBL] [Abstract][Full Text] [Related]
4. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Roberds SL; Anderson J; Basi G; Bienkowski MJ; Branstetter DG; Chen KS; Freedman SB; Frigon NL; Games D; Hu K; Johnson-Wood K; Kappenman KE; Kawabe TT; Kola I; Kuehn R; Lee M; Liu W; Motter R; Nichols NF; Power M; Robertson DW; Schenk D; Schoor M; Shopp GM; Shuck ME; Sinha S; Svensson KA; Tatsuno G; Tintrup H; Wijsman J; Wright S; McConlogue L
Hum Mol Genet; 2001 Jun; 10(12):1317-24. PubMed ID: 11406613
[TBL] [Abstract][Full Text] [Related]
5. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
[TBL] [Abstract][Full Text] [Related]
6. The potential of natural product vs neurodegenerative disorders: In silico study of artoflavanocoumarin as BACE-1 inhibitor.
Razzaghi-Asl N; Karimi A; Ebadi A
Comput Biol Chem; 2018 Dec; 77():307-317. PubMed ID: 30445338
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of 2'-Aminochalcone: A multi-target approach to find drug candidates to treat Alzheimer's disease.
Sakata RP; Antoniolli G; Lancellotti M; Kawano DF; Guimarães Barbosa E; Almeida WP
Bioorg Chem; 2020 Oct; 103():104201. PubMed ID: 32890999
[TBL] [Abstract][Full Text] [Related]
8. In silico repurposing of antipsychotic drugs for Alzheimer's disease.
Kumar S; Chowdhury S; Kumar S
BMC Neurosci; 2017 Oct; 18(1):76. PubMed ID: 29078760
[TBL] [Abstract][Full Text] [Related]
9. BACE-1 Inhibitors Targeting Alzheimer's Disease.
Monteiro KLC; Dos Santos Alcântara MG; Freire NML; Brandão EM; do Nascimento VL; Dos Santos Viana LM; de Aquino TM; da Silva-Júnior EF
Curr Alzheimer Res; 2023; 20(3):131-148. PubMed ID: 37309767
[TBL] [Abstract][Full Text] [Related]
10. Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer's Disease: From In Silico to In Vivo.
Stern N; Gacs A; Tátrai E; Flachner B; Hajdú I; Dobi K; Bágyi I; Dormán G; Lőrincz Z; Cseh S; Kígyós A; Tóvári J; Goldblum A
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361906
[TBL] [Abstract][Full Text] [Related]
11. Repurposing of phyto-ligand molecules from the honey bee products for Alzheimer's disease as novel inhibitors of BACE-1: small molecule bioinformatics strategies as amyloid-based therapy.
Nisa N; Rasmita B; Arati C; Uditraj C; Siddhartha R; Dinata R; Bhanushree B; Bidanchi RM; Manikandan B; Laskar SA; Abinash G; Pori B; Roy VK; Gurusubramanian G
Environ Sci Pollut Res Int; 2023 Apr; 30(17):51143-51169. PubMed ID: 36808033
[TBL] [Abstract][Full Text] [Related]
12. Concatenation of molecular docking and molecular simulation of BACE-1, γ-secretase targeted ligands: in pursuit of Alzheimer's treatment.
Jabir NR; Rehman MT; Alsolami K; Shakil S; Zughaibi TA; Alserihi RF; Khan MS; AlAjmi MF; Tabrez S
Ann Med; 2021 Dec; 53(1):2332-2344. PubMed ID: 34889159
[TBL] [Abstract][Full Text] [Related]
13. Design, Synthesis and Evaluation of 2,4,6-substituted Pyrimidine Derivatives as BACE-1 Inhibitor: Plausible Lead for Alzheimer's Disease.
Jain P; Wadhwa PK; Jadhav HR
Med Chem; 2021; 17(10):1194-1206. PubMed ID: 33349218
[TBL] [Abstract][Full Text] [Related]
14. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.
Li R; Lindholm K; Yang LB; Yue X; Citron M; Yan R; Beach T; Sue L; Sabbagh M; Cai H; Wong P; Price D; Shen Y
Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3632-7. PubMed ID: 14978286
[TBL] [Abstract][Full Text] [Related]
15. Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.
Fu H; Dou J; Li W; Cui W; Mak S; Hu Q; Luo J; Lam CS; Pang Y; Youdim MB; Han Y
Eur J Pharmacol; 2009 Nov; 623(1-3):14-21. PubMed ID: 19765582
[TBL] [Abstract][Full Text] [Related]
16. Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.
Hook VY; Toneff T; Aaron W; Yasothornsrikul S; Bundey R; Reisine T
J Neurochem; 2002 Apr; 81(2):237-56. PubMed ID: 12064471
[TBL] [Abstract][Full Text] [Related]
17. Potent BACE-1 inhibitor design using pharmacophore modeling, in silico screening and molecular docking studies.
John S; Thangapandian S; Sakkiah S; Lee KW
BMC Bioinformatics; 2011 Feb; 12 Suppl 1(Suppl 1):S28. PubMed ID: 21342558
[TBL] [Abstract][Full Text] [Related]
18. Exploring the Molecular Structural Requirements of Flavonoids as Beta- Secretase-1 Inhibitors Using Molecular Modeling Studies.
More UA; Noolvi MN; Kumar D; Tripathi A
Curr Drug Discov Technol; 2023; 20(3):e290323215095. PubMed ID: 36999415
[TBL] [Abstract][Full Text] [Related]
19. In-silico Studies and Biological Activity of Potential BACE-1 Inhibitors.
Arya R; Paliwal S; Gupta SP; Sharma S; Madan K; Mishra A; Verma K; Chauhan N
Comb Chem High Throughput Screen; 2021; 24(5):729-736. PubMed ID: 32957879
[TBL] [Abstract][Full Text] [Related]
20. Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production.
Strömberg K; Eketjäll S; Georgievska B; Tunblad K; Eliason K; Olsson F; Radesäter AC; Klintenberg R; Arvidsson PI; von Berg S; Fälting J; Cowburn RF; Dabrowski M
FEBS J; 2015 Jan; 282(1):65-73. PubMed ID: 25303711
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]