198 related articles for article (PubMed ID: 37176010)
1. In Vivo and In Vitro Characterization of Close Analogs of Compound KA-11, a New Antiseizure Drug Candidate.
Andres-Mach M; Zagaja M; Szala-Rycaj J; Szewczyk A; Abram M; Jakubiec M; Ciepiela K; Socała K; Wlaź P; Latacz G; Khan N; Kaminski K
Int J Mol Sci; 2023 May; 24(9):. PubMed ID: 37176010
[TBL] [Abstract][Full Text] [Related]
2. Validated animal models for antiseizure drug (ASD) discovery: Advantages and potential pitfalls in ASD screening.
Barker-Haliski M; Steve White H
Neuropharmacology; 2020 May; 167():107750. PubMed ID: 31469995
[TBL] [Abstract][Full Text] [Related]
3. KA-11, a Novel Pyrrolidine-2,5-dione Derived Broad-Spectrum Anticonvulsant: Its Antiepileptogenic, Antinociceptive Properties and in Vitro Characterization.
Socała K; Mogilski S; Pieróg M; Nieoczym D; Abram M; Szulczyk B; Lubelska A; Latacz G; Doboszewska U; Wlaź P; Kamiński K
ACS Chem Neurosci; 2019 Jan; 10(1):636-648. PubMed ID: 30247871
[TBL] [Abstract][Full Text] [Related]
4. Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Koneval Z; Knox KM; Memon A; Zierath DK; White HS; Barker-Haliski M
Epilepsia; 2020 Sep; 61(9):2022-2034. PubMed ID: 32757210
[TBL] [Abstract][Full Text] [Related]
5. Animal Models of Seizures and Epilepsy: Past, Present, and Future Role for the Discovery of Antiseizure Drugs.
Löscher W
Neurochem Res; 2017 Jul; 42(7):1873-1888. PubMed ID: 28290134
[TBL] [Abstract][Full Text] [Related]
6. New Phenylglycinamide Derivatives with Hybrid Structure as Candidates for New Broad-Spectrum Anticonvulsants.
Jakubiec M; Abram M; Zagaja M; Andres-Mach M; Szewczyk A; Latacz G; Szulczyk B; Socała K; Nieoczym D; Wlaź P; Metcalf CS; Wilcox K; Kamiński RM; Kamiński K
Cells; 2022 Jun; 11(12):. PubMed ID: 35740990
[TBL] [Abstract][Full Text] [Related]
7. Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides.
Abram M; Jakubiec M; Rapacz A; Mogilski S; Latacz G; Szulczyk B; Szafarz M; Socała K; Nieoczym D; Wyska E; Wlaź P; Kamiński RM; Kamiński K
Int J Mol Sci; 2021 Dec; 22(23):. PubMed ID: 34884898
[TBL] [Abstract][Full Text] [Related]
8. Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs.
West PJ; Thomson K; Billingsley P; Pruess T; Rueda C; Saunders GW; Smith MD; Metcalf CS; Wilcox KS
Exp Neurol; 2022 Mar; 349():113954. PubMed ID: 34922908
[TBL] [Abstract][Full Text] [Related]
9. Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A
Copmans D; Rateb M; Tabudravu JN; Pérez-Bonilla M; Dirkx N; Vallorani R; Diaz C; Pérez Del Palacio J; Smith AJ; Ebel R; Reyes F; Jaspars M; de Witte PAM
ACS Chem Neurosci; 2018 Jul; 9(7):1652-1662. PubMed ID: 29672015
[TBL] [Abstract][Full Text] [Related]
10.
Gunia-Krzyżak A; Żesławska E; Słoczyńska K; Żelaszczyk D; Sowa A; Koczurkiewicz-Adamczyk P; Popiół J; Nitek W; Pękala E; Marona H
Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32575479
[TBL] [Abstract][Full Text] [Related]
11. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.
White HS; Alex AB; Pollock A; Hen N; Shekh-Ahmad T; Wilcox KS; McDonough JH; Stables JP; Kaufmann D; Yagen B; Bialer M
Epilepsia; 2012 Jan; 53(1):134-46. PubMed ID: 22150444
[TBL] [Abstract][Full Text] [Related]
12. Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Characterization in Rodent Seizure and Epilepsy Models.
Leclercq K; Matagne A; Provins L; Klitgaard H; Kaminski RM
J Pharmacol Exp Ther; 2020 Jan; 372(1):11-20. PubMed ID: 31619464
[TBL] [Abstract][Full Text] [Related]
13. The novel dual-mechanism Kv7 potassium channel/TSPO receptor activator GRT-X is more effective than the Kv7 channel opener retigabine in the 6-Hz refractory seizure mouse model.
Bloms-Funke P; Bankstahl M; Bankstahl J; Kneip C; Schröder W; Löscher W
Neuropharmacology; 2022 Feb; 203():108884. PubMed ID: 34785163
[TBL] [Abstract][Full Text] [Related]
14. Lamotrigine-resistant corneal-kindled mice: A model of pharmacoresistant partial epilepsy for moderate-throughput drug discovery.
Koneval Z; Knox KM; White HS; Barker-Haliski M
Epilepsia; 2018 Jun; 59(6):1245-1256. PubMed ID: 29750337
[TBL] [Abstract][Full Text] [Related]
15. Discovery of (
Abram M; Jakubiec M; Reeb K; Cheng MH; Gedschold R; Rapacz A; Mogilski S; Socała K; Nieoczym D; Szafarz M; Latacz G; Szulczyk B; Kalinowska-Tłuścik J; Gawel K; Esguerra CV; Wyska E; Müller CE; Bahar I; Fontana ACK; Wlaź P; Kamiński RM; Kamiński K
J Med Chem; 2022 Sep; 65(17):11703-11725. PubMed ID: 35984707
[No Abstract] [Full Text] [Related]
16. The Pharmacology and Clinical Efficacy of Antiseizure Medications: From Bromide Salts to Cenobamate and Beyond.
Löscher W; Klein P
CNS Drugs; 2021 Sep; 35(9):935-963. PubMed ID: 34145528
[TBL] [Abstract][Full Text] [Related]
17. The current approach of the Epilepsy Therapy Screening Program contract site for identifying improved therapies for the treatment of pharmacoresistant seizures in epilepsy.
Wilcox KS; West PJ; Metcalf CS
Neuropharmacology; 2020 Apr; 166():107811. PubMed ID: 31790717
[TBL] [Abstract][Full Text] [Related]
18. Development and pharmacologic characterization of the rat 6 Hz model of partial seizures.
Metcalf CS; West PJ; Thomson KE; Edwards SF; Smith MD; White HS; Wilcox KS
Epilepsia; 2017 Jun; 58(6):1073-1084. PubMed ID: 28449218
[TBL] [Abstract][Full Text] [Related]
19. The Search for New Screening Models of Pharmacoresistant Epilepsy: Is Induction of Acute Seizures in Epileptic Rodents a Suitable Approach?
Löscher W
Neurochem Res; 2017 Jul; 42(7):1926-1938. PubMed ID: 27502939
[TBL] [Abstract][Full Text] [Related]
20. Recurrent epileptiform discharges in the medial entorhinal cortex of kainate-treated rats are differentially sensitive to antiseizure drugs.
West PJ; Saunders GW; Billingsley P; Smith MD; White HS; Metcalf CS; Wilcox KS
Epilepsia; 2018 Nov; 59(11):2035-2048. PubMed ID: 30328622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]