BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 37193711)

  • 1. HUNK inhibits epithelial-mesenchymal transition of CRC via direct phosphorylation of GEF-H1 and activating RhoA/LIMK-1/CFL-1.
    Han X; Jiang S; Gu Y; Ding L; Zhao E; Cao D; Wang X; Wen Y; Pan Y; Yan X; Duan L; Sun M; Zhou T; Liu Y; Hu H; Ye Q; Gao S
    Cell Death Dis; 2023 May; 14(5):327. PubMed ID: 37193711
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization.
    Yamahashi Y; Saito Y; Murata-Kamiya N; Hatakeyama M
    J Biol Chem; 2011 Dec; 286(52):44576-84. PubMed ID: 22072711
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia inhibits HUNK kinase activity to induce epithelial-mesenchymal transition.
    Jiang S; Han X; Zhao Z; Song D; Cheng S; Liu T; Zhao X; Gu Y; Duan L; Gao S
    Biochem Biophys Res Commun; 2023 Nov; 681():271-275. PubMed ID: 37793312
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NDR2 kinase contributes to cell invasion and cytokinesis defects induced by the inactivation of RASSF1A tumor-suppressor gene in lung cancer cells.
    Keller M; Dubois F; Teulier S; Martin APJ; Levallet J; Maille E; Brosseau S; Elie N; Hergovich A; Bergot E; Camonis J; Zalcman G; Levallet G
    J Exp Clin Cancer Res; 2019 Apr; 38(1):158. PubMed ID: 30979377
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells.
    Eitaki M; Yamamori T; Meike S; Yasui H; Inanami O
    BMC Cancer; 2012 Oct; 12():469. PubMed ID: 23057787
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
    Gulhati P; Bowen KA; Liu J; Stevens PD; Rychahou PG; Chen M; Lee EY; Weiss HL; O'Connor KL; Gao T; Evers BM
    Cancer Res; 2011 May; 71(9):3246-56. PubMed ID: 21430067
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling.
    Cheng IK; Tsang BC; Lai KP; Ching AK; Chan AW; To KF; Lai PB; Wong N
    J Pathol; 2012 Dec; 228(4):575-85. PubMed ID: 22847784
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The epidermal growth factor receptor mediates tumor necrosis factor-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular epithelium.
    Kakiashvili E; Dan Q; Vandermeer M; Zhang Y; Waheed F; Pham M; Szászi K
    J Biol Chem; 2011 Mar; 286(11):9268-79. PubMed ID: 21212278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge.
    Nalbant P; Chang YC; Birkenfeld J; Chang ZF; Bokoch GM
    Mol Biol Cell; 2009 Sep; 20(18):4070-82. PubMed ID: 19625450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HUNK phosphorylates EGFR to regulate breast cancer metastasis.
    Williams CB; Phelps-Polirer K; Dingle IP; Williams CJ; Rhett MJ; Eblen ST; Armeson K; Hill EG; Yeh ES
    Oncogene; 2020 Jan; 39(5):1112-1124. PubMed ID: 31597954
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases.
    Birkenfeld J; Nalbant P; Bohl BP; Pertz O; Hahn KM; Bokoch GM
    Dev Cell; 2007 May; 12(5):699-712. PubMed ID: 17488622
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling.
    Cao J; Yang T; Tang D; Zhou F; Qian Y; Zou X
    Pathol Res Pract; 2019 May; 215(5):1012-1019. PubMed ID: 30846413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.
    Waheed F; Dan Q; Amoozadeh Y; Zhang Y; Tanimura S; Speight P; Kapus A; Szászi K
    Mol Biol Cell; 2013 Apr; 24(7):1068-82. PubMed ID: 23389627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.
    Quintela-Fandino M; Arpaia E; Brenner D; Goh T; Yeung FA; Blaser H; Alexandrova R; Lind EF; Tusche MW; Wakeham A; Ohashi PS; Mak TW
    Proc Natl Acad Sci U S A; 2010 Feb; 107(6):2622-7. PubMed ID: 20133759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Contribution of guanine exchange factor H1 in phorbol ester-induced apoptosis.
    Chang YC; Lee HH; Chen YJ; Bokoch GM; Chang ZF
    Cell Death Differ; 2006 Dec; 13(12):2023-32. PubMed ID: 16601754
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of β-catenin signaling.
    Zhang JX; Mai SJ; Huang XX; Wang FW; Liao YJ; Lin MC; Kung HF; Zeng YX; Xie D
    Ann Oncol; 2014 Nov; 25(11):2196-2204. PubMed ID: 25193986
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of guanine nucleotide exchange factor-H1 in complement-mediated RhoA activation in glomerular epithelial cells.
    Mouawad F; Aoudjit L; Jiang R; Szaszi K; Takano T
    J Biol Chem; 2014 Feb; 289(7):4206-18. PubMed ID: 24356971
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CSRP2 suppresses colorectal cancer progression
    Chen L; Long X; Duan S; Liu X; Chen J; Lan J; Liu X; Huang W; Geng J; Zhou J
    Theranostics; 2020; 10(24):11063-11079. PubMed ID: 33042270
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Claudin-2 suppresses GEF-H1, RHOA, and MRTF, thereby impacting proliferation and profibrotic phenotype of tubular cells.
    Dan Q; Shi Y; Rabani R; Venugopal S; Xiao J; Anwer S; Ding M; Speight P; Pan W; Alexander RT; Kapus A; Szászi K
    J Biol Chem; 2019 Oct; 294(42):15446-15465. PubMed ID: 31481470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets.
    Comer S; Nagy Z; Bolado A; von Kriegsheim A; Gambaryan S; Walter U; Pagel O; Zahedi RP; Jurk K; Smolenski A
    J Thromb Haemost; 2020 Nov; 18(11):3002-3012. PubMed ID: 32692911
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.