BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 37204046)

  • 1. Exploiting Cancer Vulnerabilities by Blocking of the DHODH and GPX4 Pathways: A Multifunctional Bodipy/PROTAC Nanoplatform for the Efficient Synergistic Ferroptosis Therapy.
    Yao L; Yang N; Zhou W; Akhtar MH; Zhou W; Liu C; Song S; Li Y; Han W; Yu C
    Adv Healthc Mater; 2023 Oct; 12(26):e2300871. PubMed ID: 37204046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.
    Mao C; Liu X; Zhang Y; Lei G; Yan Y; Lee H; Koppula P; Wu S; Zhuang L; Fang B; Poyurovsky MV; Olszewski K; Gan B
    Nature; 2021 May; 593(7860):586-590. PubMed ID: 33981038
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A GPX4 non-enzymatic domain and MDM2 targeting peptide PROTAC for acute lymphoid leukemia therapy through ferroptosis induction.
    Niu F; Yang R; Feng H; Liu Y; Liu R; Ma B
    Biochem Biophys Res Commun; 2023 Dec; 684():149125. PubMed ID: 37897912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Warburg effect modulates DHODH role in ferroptosis: a review.
    Amos A; Amos A; Wu L; Xia H
    Cell Commun Signal; 2023 May; 21(1):100. PubMed ID: 37147673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutathione depletion and dihydroorotate dehydrogenase inhibition actuated ferroptosis-augment to surmount triple-negative breast cancer.
    Zhou TJ; Zhang MM; Liu DM; Huang LL; Yu HQ; Wang Y; Xing L; Jiang HL
    Biomaterials; 2024 Mar; 305():122447. PubMed ID: 38154441
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual degradation mechanism of GPX4 degrader in induction of ferroptosis exerting anti-resistant tumor effect.
    Wang C; Zheng C; Wang H; Shui S; Jin H; Liu G; Xu F; Liu Z; Zhang L; Sun D; Xu P
    Eur J Med Chem; 2023 Feb; 247():115072. PubMed ID: 36603510
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase.
    Zhang S; Kang L; Dai X; Chen J; Chen Z; Wang M; Jiang H; Wang X; Bu S; Liu X; Zhang G; Tang H
    Free Radic Biol Med; 2022 Nov; 193(Pt 1):202-212. PubMed ID: 36228830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DHODH tangoing with GPX4 on the ferroptotic stage.
    Wang F; Min J
    Signal Transduct Target Ther; 2021 Jun; 6(1):244. PubMed ID: 34145214
    [No Abstract]   [Full Text] [Related]  

  • 9. Mitochondria-Targeted Prodrug Nanoassemblies for Efficient Ferroptosis-Based Therapy via Devastating Ferroptosis Defense Systems.
    Liu N; Lin Q; Huang Z; Liu C; Qin J; Yu Y; Chen W; Zhang J; Jiang M; Gao X; Huo S; Zhu X
    ACS Nano; 2024 Mar; 18(11):7945-7958. PubMed ID: 38452275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression.
    Hai Y; Fan R; Zhao T; Lin R; Zhuang J; Deng A; Meng S; Hou Z; Wei G
    Pharmacol Res; 2024 Apr; 202():107115. PubMed ID: 38423231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
    Amos A; Jiang N; Zong D; Gu J; Zhou J; Yin L; He X; Xu Y; Wu L
    BMC Cancer; 2023 Feb; 23(1):117. PubMed ID: 36737723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic Functional Nanomedicine Enhances Ferroptosis Therapy for Breast Tumors by a Blocking Defensive Redox System.
    Chen S; Yang J; Liang Z; Li Z; Xiong W; Fan Q; Shen Z; Liu J; Xu Y
    ACS Appl Mater Interfaces; 2023 Jan; 15(2):2705-2713. PubMed ID: 36622364
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting GPX4 in human cancer: Implications of ferroptosis induction for tackling cancer resilience.
    Lee J; Roh JL
    Cancer Lett; 2023 Apr; 559():216119. PubMed ID: 36893895
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dihydroorotate dehydrogenase promotes cell proliferation and suppresses cell death in esophageal squamous cell carcinoma and colorectal carcinoma.
    Shi ZZ; Jin X; Li WT; Tao H; Song SJ; Fan ZW; Jiang W; Liang JW; Bai J
    Transl Cancer Res; 2023 Sep; 12(9):2294-2307. PubMed ID: 37859742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway.
    Li D; Lu X; Xu G; Liu S; Gong Z; Lu F; Xia X; Jiang J; Wang H; Zou F; Ma X
    CNS Neurosci Ther; 2023 Jul; 29(7):1923-1939. PubMed ID: 36942513
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DHODH Inhibition Exerts Synergistic Therapeutic Effect with Cisplatin to Induce Ferroptosis in Cervical Cancer through Regulating mTOR Pathway.
    Jiang M; Song Y; Liu H; Jin Y; Li R; Zhu X
    Cancers (Basel); 2023 Jan; 15(2):. PubMed ID: 36672495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An all-in-one biomimetic iron-small interfering RNA nanoplatform induces ferroptosis for cancer therapy.
    Huang S; Le H; Hong G; Chen G; Zhang F; Lu L; Zhang X; Qiu Y; Wang Z; Zhang Q; Ouyang G; Shen J
    Acta Biomater; 2022 Aug; 148():244-257. PubMed ID: 35709941
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of proteolysis-targeting chimeras (PROTACs) as degraders of glutathione peroxidase 4.
    Cai M; Ma F; Hu C; Li H; Cao F; Li Y; Dong J; Qin JJ
    Bioorg Med Chem; 2023 Jul; 90():117352. PubMed ID: 37257255
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells.
    Wang H; Wang C; Li B; Zheng C; Liu G; Liu Z; Zhang L; Xu P
    Eur J Med Chem; 2023 Jun; 254():115343. PubMed ID: 37087895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prospects for Anti-Tumor Mechanism and Potential Clinical Application Based on Glutathione Peroxidase 4 Mediated Ferroptosis.
    Chen M; Shi Z; Sun Y; Ning H; Gu X; Zhang L
    Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36675129
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.