BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 37216195)

  • 1. Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase.
    Chisuga T; Murakami S; Miyanaga A; Kudo F; Eguchi T
    ACS Chem Biol; 2023 Jun; 18(6):1398-1404. PubMed ID: 37216195
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Insight into the Reaction Mechanism of Ketosynthase-Like Decarboxylase in a Loading Module of Modular Polyketide Synthases.
    Chisuga T; Nagai A; Miyanaga A; Goto E; Kishikawa K; Kudo F; Eguchi T
    ACS Chem Biol; 2022 Jan; 17(1):198-206. PubMed ID: 34985877
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A chain initiation factor common to both modular and aromatic polyketide synthases.
    Bisang C; Long PF; Cortés J; Westcott J; Crosby J; Matharu AL; Cox RJ; Simpson TJ; Staunton J; Leadlay PF
    Nature; 1999 Sep; 401(6752):502-5. PubMed ID: 10519556
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
    Tang L; Yoon YJ; Choi CY; Hutchinson CR
    Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Basis of Transient Interactions of Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase.
    Miyanaga A; Kawada K; Chisuga T; Kudo F; Eguchi T
    Biochemistry; 2023 Jan; 62(1):17-21. PubMed ID: 36512613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
    Dreier J; Khosla C
    Biochemistry; 2000 Feb; 39(8):2088-95. PubMed ID: 10684659
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.
    Feng Y; Zhang F; Huang S; Deng Z; Bai L; Zheng J
    Acta Crystallogr D Struct Biol; 2022 Jun; 78(Pt 6):779-791. PubMed ID: 35647924
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
    Liou GF; Lau J; Cane DE; Khosla C
    Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural rearrangements of a polyketide synthase module during its catalytic cycle.
    Whicher JR; Dutta S; Hansen DA; Hale WA; Chemler JA; Dosey AM; Narayan AR; Håkansson K; Sherman DH; Smith JL; Skiniotis G
    Nature; 2014 Jun; 510(7506):560-4. PubMed ID: 24965656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
    Hans M; Hornung A; Dziarnowski A; Cane DE; Khosla C
    J Am Chem Soc; 2003 May; 125(18):5366-74. PubMed ID: 12720450
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase.
    Long PF; Wilkinson CJ; Bisang CP; Cortés J; Dunster N; Oliynyk M; McCormick E; McArthur H; Mendez C; Salas JA; Staunton J; Leadlay PF
    Mol Microbiol; 2002 Mar; 43(5):1215-25. PubMed ID: 11918808
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions.
    Dell M; Tran MA; Capper MJ; Sundaram S; Fiedler J; Koehnke J; Hellmich UA; Hertweck C
    Angew Chem Int Ed Engl; 2024 Feb; 63(9):e202315850. PubMed ID: 38134222
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase.
    Chen AY; Schnarr NA; Kim CY; Cane DE; Khosla C
    J Am Chem Soc; 2006 Mar; 128(9):3067-74. PubMed ID: 16506788
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structural organization of substrate loading in iterative polyketide synthases.
    Herbst DA; Huitt-Roehl CR; Jakob RP; Kravetz JM; Storm PA; Alley JR; Townsend CA; Maier T
    Nat Chem Biol; 2018 May; 14(5):474-479. PubMed ID: 29610486
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases.
    Jenner M; Afonso JP; Bailey HR; Frank S; Kampa A; Piel J; Oldham NJ
    Angew Chem Int Ed Engl; 2015 Feb; 54(6):1817-21. PubMed ID: 25529827
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthase.
    Jiralerspong S; Rangaswamy V; Bender CL; Parry RJ
    Gene; 2001 May; 270(1-2):191-200. PubMed ID: 11404016
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of Unexpected Self-Acylation Activity of Acyl Carrier Proteins in a Modular Type I Apicomplexan Polyketide Synthase.
    Keeler AM; D'Ambrosio HK; Ganley JG; Derbyshire ER
    ACS Chem Biol; 2023 Apr; 18(4):785-793. PubMed ID: 36893402
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Vinylogous chain branching catalysed by a dedicated polyketide synthase module.
    Bretschneider T; Heim JB; Heine D; Winkler R; Busch B; Kusebauch B; Stehle T; Zocher G; Hertweck C
    Nature; 2013 Oct; 502(7469):124-8. PubMed ID: 24048471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY; Alekseyev VY; Chen AY; Tang Y; Cane DE; Khosla C
    Biochemistry; 2004 Nov; 43(44):13892-8. PubMed ID: 15518537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.