173 related articles for article (PubMed ID: 37216473)
1. Role of complementarity-determining regions 1 and 3 in pathologic amyloid formation by human immunoglobulin κ1 light chains.
Klimtchuk ES; Peterle D; Bullitt E; Connors LH; Engen JR; Gursky O
Amyloid; 2023 Dec; 30(4):364-378. PubMed ID: 37216473
[TBL] [Abstract][Full Text] [Related]
2. Role of Complementarity-Determining Regions 1 and 3 in Pathologic Amyloid Formation by Human Immunoglobulin κ1 Light Chains.
Klimtchuk ES; Peterle D; Bullitt EA; Connors LH; Engen JR; Gursky O
bioRxiv; 2023 Feb; ():. PubMed ID: 36778378
[TBL] [Abstract][Full Text] [Related]
3. A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation.
Peterle D; Klimtchuk ES; Wales TE; Georgescauld F; Connors LH; Engen JR; Gursky O
J Mol Biol; 2021 Dec; 433(24):167310. PubMed ID: 34678302
[TBL] [Abstract][Full Text] [Related]
4. Protease-sensitive regions in amyloid light chains: what a common pattern of fragmentation across organs suggests about aggregation.
Mazzini G; Ricagno S; Caminito S; Rognoni P; Milani P; Nuvolone M; Basset M; Foli A; Russo R; Merlini G; Palladini G; Lavatelli F
FEBS J; 2022 Jan; 289(2):494-506. PubMed ID: 34482629
[TBL] [Abstract][Full Text] [Related]
5. Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains.
Rottenaicher GJ; Weber B; Rührnößl F; Kazman P; Absmeier RM; Hitzenberger M; Zacharias M; Buchner J
J Biol Chem; 2021; 296():100334. PubMed ID: 33508322
[TBL] [Abstract][Full Text] [Related]
6. The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.
Morgan GJ; Kelly JW
J Mol Biol; 2016 Oct; 428(21):4280-4297. PubMed ID: 27569045
[TBL] [Abstract][Full Text] [Related]
7. Differential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils-A metric for predicting amyloid propensity.
Martin EB; Williams A; Wooliver C; Heidel RE; Adams S; Dunlap J; Ramirez-Alvarado M; Blancas-Mejia LM; Lands RH; Kennel SJ; Wall JS
PLoS One; 2017; 12(3):e0174152. PubMed ID: 28350808
[TBL] [Abstract][Full Text] [Related]
8. Dynamic protein structures in normal function and pathologic misfolding in systemic amyloidosis.
Lewkowicz E; Gursky O
Biophys Chem; 2022 Jan; 280():106699. PubMed ID: 34773861
[TBL] [Abstract][Full Text] [Related]
9. Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis.
Lavatelli F; Mazzini G; Ricagno S; Iavarone F; Rognoni P; Milani P; Nuvolone M; Swuec P; Caminito S; Tasaki M; Chaves-Sanjuan A; Urbani A; Merlini G; Palladini G
J Biol Chem; 2020 Dec; 295(49):16572-16584. PubMed ID: 32952127
[TBL] [Abstract][Full Text] [Related]
10. Decreased amyloidogenicity caused by mutational modulation of surface properties of the immunoglobulin light chain BRE variable domain.
Kobayashi Y; Tsutsumi H; Abe T; Ikeda K; Tashiro Y; Unzai S; Kamikubo H; Kataoka M; Hiroaki H; Hamada D
Biochemistry; 2014 Aug; 53(31):5162-73. PubMed ID: 25062800
[TBL] [Abstract][Full Text] [Related]
11. Effect of single point mutations in a form of systemic amyloidosis.
Bhavaraju M; Hansmann UH
Protein Sci; 2015 Sep; 24(9):1451-62. PubMed ID: 26105812
[TBL] [Abstract][Full Text] [Related]
12. The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation.
Ruiz-Zamora RA; Guillaumé S; Al-Hilaly YK; Al-Garawi Z; Rodríguez-Alvarez FJ; Zavala-Padilla G; Pérez-Carreón JI; Rodríguez-Ambriz SL; Herrera GA; Becerril-Luján B; Ochoa-Leyva A; Melendez-Zajgla J; Serpell L; Del Pozo-Yauner L
Sci Rep; 2019 Feb; 9(1):3123. PubMed ID: 30816248
[TBL] [Abstract][Full Text] [Related]
13. The critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chain.
Klimtchuk ES; Gursky O; Patel RS; Laporte KL; Connors LH; Skinner M; Seldin DC
Biochemistry; 2010 Nov; 49(45):9848-57. PubMed ID: 20936823
[TBL] [Abstract][Full Text] [Related]
14. Identification and location of a cysteinyl posttranslational modification in an amyloidogenic kappa1 light chain protein by electrospray ionization and matrix-assisted laser desorption/ionization mass spectrometry.
Lim A; Wally J; Walsh MT; Skinner M; Costello CE
Anal Biochem; 2001 Aug; 295(1):45-56. PubMed ID: 11476544
[TBL] [Abstract][Full Text] [Related]
15. Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate.
Andrich K; Hegenbart U; Kimmich C; Kedia N; Bergen HR; Schönland S; Wanker E; Bieschke J
J Biol Chem; 2017 Feb; 292(6):2328-2344. PubMed ID: 28031465
[TBL] [Abstract][Full Text] [Related]
16. A constant domain mutation in a patient-derived antibody light chain reveals principles of AL amyloidosis.
Rottenaicher GJ; Absmeier RM; Meier L; Zacharias M; Buchner J
Commun Biol; 2023 Feb; 6(1):209. PubMed ID: 36823438
[TBL] [Abstract][Full Text] [Related]
17. Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.
Poshusta TL; Sikkink LA; Leung N; Clark RJ; Dispenzieri A; Ramirez-Alvarado M
PLoS One; 2009; 4(4):e5169. PubMed ID: 19365555
[TBL] [Abstract][Full Text] [Related]
18. Identification of AL proteins from 10 λ-AL amyloidosis patients by mass spectrometry extracted from abdominal fat and heart tissue.
Baur J; Berghaus N; Schreiner S; Hegenbart U; Schönland SO; Wiese S; Huhn S; Haupt C
Amyloid; 2023 Mar; 30(1):27-37. PubMed ID: 35792725
[TBL] [Abstract][Full Text] [Related]
19. Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chains.
Connors LH; Jiang Y; Budnik M; Théberge R; Prokaeva T; Bodi KL; Seldin DC; Costello CE; Skinner M
Biochemistry; 2007 Dec; 46(49):14259-71. PubMed ID: 18004879
[TBL] [Abstract][Full Text] [Related]
20. Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Oberti L; Rognoni P; Barbiroli A; Lavatelli F; Russo R; Maritan M; Palladini G; Bolognesi M; Merlini G; Ricagno S
Sci Rep; 2017 Dec; 7(1):16809. PubMed ID: 29196671
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
