180 related articles for article (PubMed ID: 37216510)
1. Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Hegron A; Peach CJ; Tonello R; Seemann P; Teng S; Latorre R; Huebner H; Weikert D; Rientjes J; Veldhuis NA; Poole DP; Jensen DD; Thomsen ARB; Schmidt BL; Imlach WL; Gmeiner P; Bunnett NW
Proc Natl Acad Sci U S A; 2023 May; 120(22):e2220979120. PubMed ID: 37216510
[TBL] [Abstract][Full Text] [Related]
2. Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.
Jensen DD; Lieu T; Halls ML; Veldhuis NA; Imlach WL; Mai QN; Poole DP; Quach T; Aurelio L; Conner J; Herenbrink CK; Barlow N; Simpson JS; Scanlon MJ; Graham B; McCluskey A; Robinson PJ; Escriou V; Nassini R; Materazzi S; Geppetti P; Hicks GA; Christie MJ; Porter CJH; Canals M; Bunnett NW
Sci Transl Med; 2017 May; 9(392):. PubMed ID: 28566424
[TBL] [Abstract][Full Text] [Related]
3. A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
Mai QN; Shenoy P; Quach T; Retamal JS; Gondin AB; Yeatman HR; Aurelio L; Conner JW; Poole DP; Canals M; Nowell CJ; Graham B; Davis TP; Briddon SJ; Hill SJ; Porter CJH; Bunnett NW; Halls ML; Veldhuis NA
J Biol Chem; 2021; 296():100345. PubMed ID: 33515548
[TBL] [Abstract][Full Text] [Related]
4. Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain.
Latorre R; Ramírez-Garcia PD; Hegron A; Grace JL; Retamal JS; Shenoy P; Tran M; Aurelio L; Flynn B; Poole DP; Klein-Cloud R; Jensen DD; Davis TP; Schmidt BL; Quinn JF; Whittaker MR; Veldhuis NA; Bunnett NW
Biomaterials; 2022 Jun; 285():121536. PubMed ID: 35533442
[TBL] [Abstract][Full Text] [Related]
5. A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Ramírez-García PD; Retamal JS; Shenoy P; Imlach W; Sykes M; Truong N; Constandil L; Pelissier T; Nowell CJ; Khor SY; Layani LM; Lumb C; Poole DP; Lieu T; Stewart GD; Mai QN; Jensen DD; Latorre R; Scheff NN; Schmidt BL; Quinn JF; Whittaker MR; Veldhuis NA; Davis TP; Bunnett NW
Nat Nanotechnol; 2019 Dec; 14(12):1150-1159. PubMed ID: 31686009
[TBL] [Abstract][Full Text] [Related]
6. Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Yarwood RE; Imlach WL; Lieu T; Veldhuis NA; Jensen DD; Klein Herenbrink C; Aurelio L; Cai Z; Christie MJ; Poole DP; Porter CJH; McLean P; Hicks GA; Geppetti P; Halls ML; Canals M; Bunnett NW
Proc Natl Acad Sci U S A; 2017 Nov; 114(46):12309-12314. PubMed ID: 29087309
[TBL] [Abstract][Full Text] [Related]
7. Endothelin-converting enzyme 1 and β-arrestins exert spatiotemporal control of substance P-induced inflammatory signals.
Jensen DD; Halls ML; Murphy JE; Canals M; Cattaruzza F; Poole DP; Lieu T; Koon HW; Pothoulakis C; Bunnett NW
J Biol Chem; 2014 Jul; 289(29):20283-94. PubMed ID: 24898255
[TBL] [Abstract][Full Text] [Related]
8. Hepatoblastoma cells express truncated neurokinin-1 receptor and can be growth inhibited by aprepitant in vitro and in vivo.
Berger M; Neth O; Ilmer M; Garnier A; Salinas-Martín MV; de Agustín Asencio JC; von Schweinitz D; Kappler R; Muñoz M
J Hepatol; 2014 May; 60(5):985-94. PubMed ID: 24412605
[TBL] [Abstract][Full Text] [Related]
9. Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system.
Poole DP; Lieu T; Pelayo JC; Eriksson EM; Veldhuis NA; Bunnett NW
Am J Physiol Gastrointest Liver Physiol; 2015 Aug; 309(4):G248-59. PubMed ID: 26138465
[TBL] [Abstract][Full Text] [Related]
10. Recycling and resensitization of the neurokinin 1 receptor. Influence of agonist concentration and Rab GTPases.
Roosterman D; Cottrell GS; Schmidlin F; Steinhoff M; Bunnett NW
J Biol Chem; 2004 Jul; 279(29):30670-9. PubMed ID: 15128739
[TBL] [Abstract][Full Text] [Related]
11. The SP/NK1R system promotes the proliferation of breast cancer cells through NF-κB-mediated inflammatory responses.
Jafarinezhad S; Assaran Darban R; Javid H; Hashemy SI
Cell Biochem Biophys; 2023 Dec; 81(4):787-794. PubMed ID: 37740877
[TBL] [Abstract][Full Text] [Related]
12. Dynamin and Rab5a-dependent trafficking and signaling of the neurokinin 1 receptor.
Schmidlin F; Dery O; DeFea KO; Slice L; Patierno S; Sternini C; Grady EF; Bunnett NW
J Biol Chem; 2001 Jul; 276(27):25427-37. PubMed ID: 11306580
[TBL] [Abstract][Full Text] [Related]
13. Substance P dependence of endosomal fusion during bladder inflammation.
Hammond TG; Saban R; Bost KL; Harris HW; Kaysen JH; Goda FO; Wang XC; Lewis FC; Navar GL; Campbell WC; Bjorling DE; Saban M; Zeidel ML
Am J Physiol Renal Physiol; 2000 Mar; 278(3):F440-51. PubMed ID: 10710549
[TBL] [Abstract][Full Text] [Related]
14. SP/NK1R system regulates carcinogenesis in prostate cancer: Shedding light on the antitumoral function of aprepitant.
Ebrahimi S; Mirzavi F; Aghaee-Bakhtiari SH; Hashemy SI
Biochim Biophys Acta Mol Cell Res; 2022 May; 1869(5):119221. PubMed ID: 35134443
[TBL] [Abstract][Full Text] [Related]
15. Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling.
Roosterman D; Cottrell GS; Padilla BE; Muller L; Eckman CB; Bunnett NW; Steinhoff M
Proc Natl Acad Sci U S A; 2007 Jul; 104(28):11838-43. PubMed ID: 17592116
[TBL] [Abstract][Full Text] [Related]
16. Substance P-induced trafficking of beta-arrestins. The role of beta-arrestins in endocytosis of the neurokinin-1 receptor.
McConalogue K; Déry O; Lovett M; Wong H; Walsh JH; Grady EF; Bunnett NW
J Biol Chem; 1999 Jun; 274(23):16257-68. PubMed ID: 10347182
[TBL] [Abstract][Full Text] [Related]
17. The Effect of Blocking Neurokinin-1 Receptor by Aprepitant on the Inflammatory and Apoptosis Pathways in Human Ovarian Cancer Cells.
AlAlikhan A; Ghahremanloo A; Javid H; Ebrahimi S; Hashemy SI
Cell Biochem Biophys; 2022 Dec; 80(4):819-827. PubMed ID: 36197642
[TBL] [Abstract][Full Text] [Related]
18. Potential in vitro therapeutic effects of targeting SP/NK1R system in cervical cancer.
Mozafari M; Ebrahimi S; Darban RA; Hashemy SI
Mol Biol Rep; 2022 Feb; 49(2):1067-1076. PubMed ID: 34766230
[TBL] [Abstract][Full Text] [Related]
19. Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons.
Taylor BK; Fu W; Kuphal KE; Stiller CO; Winter MK; Chen W; Corder GF; Urban JH; McCarson KE; Marvizon JC
Neuroscience; 2014 Jan; 256():178-94. PubMed ID: 24184981
[TBL] [Abstract][Full Text] [Related]
20. Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons.
Yu YJ; Arttamangkul S; Evans CJ; Williams JT; von Zastrow M
J Neurosci; 2009 Jan; 29(1):222-33. PubMed ID: 19129399
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]