149 related articles for article (PubMed ID: 37232536)
1. Repressing expression of difficult-to-express recombinant proteins during the selection process increases productivity of CHO stable pools.
Maltais JS; Lord-Dufour S; Morasse A; Stuible M; Loignon M; Durocher Y
Biotechnol Bioeng; 2023 Oct; 120(10):2840-2852. PubMed ID: 37232536
[TBL] [Abstract][Full Text] [Related]
2. Reducing recombinant protein expression during CHO pool selection enhances frequency of high-producing cells.
Poulain A; Mullick A; Massie B; Durocher Y
J Biotechnol; 2019 Apr; 296():32-41. PubMed ID: 30885656
[TBL] [Abstract][Full Text] [Related]
3. Rapid protein production from stable CHO cell pools using plasmid vector and the cumate gene-switch.
Poulain A; Perret S; Malenfant F; Mullick A; Massie B; Durocher Y
J Biotechnol; 2017 Aug; 255():16-27. PubMed ID: 28625678
[TBL] [Abstract][Full Text] [Related]
4. A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens.
Joubert S; Stuible M; Lord-Dufour S; Lamoureux L; Vaillancourt F; Perret S; Ouimet M; Pelletier A; Bisson L; Mahimkar R; Pham PL; L Ecuyer-Coelho H; Roy M; Voyer R; Baardsnes J; Sauvageau J; St-Michael F; Robotham A; Kelly J; Acel A; Schrag JD; El Bakkouri M; Durocher Y
Biotechnol Bioeng; 2023 Jul; 120(7):1746-1761. PubMed ID: 36987713
[TBL] [Abstract][Full Text] [Related]
5. Selection of CHO host and recombinant cell pools by inhibition of the proteasome results in enhanced product yields and cell specific productivity.
Knight TJ; Turner S; Jaques CM; Smales CM
J Biotechnol; 2021 Aug; 337():35-45. PubMed ID: 34171439
[TBL] [Abstract][Full Text] [Related]
6. Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools.
Balasubramanian S; Matasci M; Kadlecova Z; Baldi L; Hacker DL; Wurm FM
J Biotechnol; 2015 Apr; 200():61-9. PubMed ID: 25758242
[TBL] [Abstract][Full Text] [Related]
7. STEP® vectors for rapid generation of stable transfected CHO cell pools and clones with high expression levels and product quality homogeneity of difficult-to-express proteins.
Luthra A; Spanjaard RA; Cheema S; Veith N; Kober L; Wang Y; Jing T; Zhao Y; Hoeksema F; Yallop C; Havenga M; Bakker WAM
Protein Expr Purif; 2021 Oct; 186():105920. PubMed ID: 34044134
[TBL] [Abstract][Full Text] [Related]
8. Utilizing targeted integration CHO pools to potentially accelerate the GMP manufacturing of monoclonal and bispecific antibodies.
Barnard GC; Zhou M; Shen A; Yuk IH; Laird MW
Biotechnol Prog; 2024; 40(1):e3399. PubMed ID: 37874920
[TBL] [Abstract][Full Text] [Related]
9. High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch.
Gaillet B; Gilbert R; Broussau S; Pilotte A; Malenfant F; Mullick A; Garnier A; Massie B
Biotechnol Bioeng; 2010 Jun; 106(2):203-15. PubMed ID: 20178120
[TBL] [Abstract][Full Text] [Related]
10. Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics.
Lin PC; Chan KF; Kiess IA; Tan J; Shahreel W; Wong SY; Song Z
MAbs; 2019 Jul; 11(5):965-976. PubMed ID: 31043114
[TBL] [Abstract][Full Text] [Related]
11. The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability.
Matasci M; Baldi L; Hacker DL; Wurm FM
Biotechnol Bioeng; 2011 Sep; 108(9):2141-50. PubMed ID: 21495018
[TBL] [Abstract][Full Text] [Related]
12. High-level production of wild-type and oxidation-resistant recombinant alpha-1-antitrypsin in glycoengineered CHO cells.
Koyuturk I; Kedia S; Robotham A; Star A; Brochu D; Sauvageau J; Kelly J; Gilbert M; Durocher Y
Biotechnol Bioeng; 2022 Sep; 119(9):2331-2344. PubMed ID: 35508753
[TBL] [Abstract][Full Text] [Related]
13. Weak promoters to drive selection marker expression: Improvement of cell line development process for therapeutic protein production in CHO-K1 cells.
Grindes L; Florimond C; Ribault S; Raymond C; Dieryck W; Joucla G; Corbin C
J Biotechnol; 2023 Jun; 369():43-54. PubMed ID: 37149043
[TBL] [Abstract][Full Text] [Related]
14. Overexpression of Serpinb1 in Chinese hamster ovary cells increases recombinant IgG productivity.
Lin N; Brooks J; Sealover N; George HJ; Kayser KJ
J Biotechnol; 2015 Jan; 193():91-9. PubMed ID: 25444873
[TBL] [Abstract][Full Text] [Related]
15. Limiting the metabolic burden of recombinant protein expression during selection yields pools with higher expression levels.
Ong EC; Smidt P; McGrew JT
Biotechnol Prog; 2019 Sep; 35(5):e2839. PubMed ID: 31090257
[TBL] [Abstract][Full Text] [Related]
16. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Figueroa B; Ailor E; Osborne D; Hardwick JM; Reff M; Betenbaugh MJ
Biotechnol Bioeng; 2007 Jul; 97(4):877-92. PubMed ID: 17099908
[TBL] [Abstract][Full Text] [Related]
17. Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production.
Budge JD; Knight TJ; Povey J; Roobol J; Brown IR; Singh G; Dean A; Turner S; Jaques CM; Young RJ; Racher AJ; Smales CM
Metab Eng; 2020 Jan; 57():203-216. PubMed ID: 31805379
[TBL] [Abstract][Full Text] [Related]
18. miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.
Fischer S; Marquart KF; Pieper LA; Fieder J; Gamer M; Gorr I; Schulz P; Bradl H
Biotechnol Bioeng; 2017 Jul; 114(7):1495-1510. PubMed ID: 28262952
[TBL] [Abstract][Full Text] [Related]
19. Generation of stable Chinese hamster ovary pools yielding antibody titers of up to 7.6 g/L using the piggyBac transposon system.
Rajendra Y; Peery RB; Barnard GC
Biotechnol Prog; 2016 Sep; 32(5):1301-1307. PubMed ID: 27254818
[TBL] [Abstract][Full Text] [Related]
20. Generation of High Expressing Chinese Hamster Ovary Cell Pools Using the Leap-In Transposon System.
Balasubramanian S; Peery RB; Minshull J; Lee M; White R; Kelly RM; Barnard GC
Biotechnol J; 2018 Oct; 13(10):e1700748. PubMed ID: 29797786
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
