BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 37235776)

  • 1. Total Chemical Synthesis of Glycosylated TREM2 Ectodomain.
    Wijegunawardena G; Castillo E; Henrickson B; Davis R; Condello C; Wu H
    ACS Chem Neurosci; 2023 Jun; 14(11):2243-2251. PubMed ID: 37235776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of TREM2 N-glycans in trafficking to the cell surface and signal transduction of TREM2.
    Shirotani K; Hatta D; Wakita N; Watanabe K; Iwata N
    J Biochem; 2022 Dec; 172(6):347-353. PubMed ID: 36095053
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
    McQuade A; Kang YJ; Hasselmann J; Jairaman A; Sotelo A; Coburn M; Shabestari SK; Chadarevian JP; Fote G; Tu CH; Danhash E; Silva J; Martinez E; Cotman C; Prieto GA; Thompson LM; Steffan JS; Smith I; Davtyan H; Cahalan M; Cho H; Blurton-Jones M
    Nat Commun; 2020 Oct; 11(1):5370. PubMed ID: 33097708
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid-β by microglia.
    Huang S; Liao X; Wu J; Zhang X; Li Y; Xiang D; Luo S
    FEBS Lett; 2022 Apr; 596(8):1059-1071. PubMed ID: 35292963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
    Schlepckow K; Kleinberger G; Fukumori A; Feederle R; Lichtenthaler SF; Steiner H; Haass C
    EMBO Mol Med; 2017 Oct; 9(10):1356-1365. PubMed ID: 28855300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
    Popescu AS; Butler CA; Allendorf DH; Piers TM; Mallach A; Roewe J; Reinhardt P; Cinti A; Redaelli L; Boudesco C; Pradier L; Pocock JM; Thornton P; Brown GC
    Glia; 2023 Apr; 71(4):974-990. PubMed ID: 36480007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
    Wang Y; Cella M; Mallinson K; Ulrich JD; Young KL; Robinette ML; Gilfillan S; Krishnan GM; Sudhakar S; Zinselmeyer BH; Holtzman DM; Cirrito JR; Colonna M
    Cell; 2015 Mar; 160(6):1061-71. PubMed ID: 25728668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Disease-Associated Mutations of TREM2 Alter the Processing of N-Linked Oligosaccharides in the Golgi Apparatus.
    Park JS; Ji IJ; An HJ; Kang MJ; Kang SW; Kim DH; Yoon SY
    Traffic; 2015 May; 16(5):510-8. PubMed ID: 25615530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
    Ulland TK; Song WM; Huang SC; Ulrich JD; Sergushichev A; Beatty WL; Loboda AA; Zhou Y; Cairns NJ; Kambal A; Loginicheva E; Gilfillan S; Cella M; Virgin HW; Unanue ER; Wang Y; Artyomov MN; Holtzman DM; Colonna M
    Cell; 2017 Aug; 170(4):649-663.e13. PubMed ID: 28802038
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells.
    Varnum MM; Clayton KA; Yoshii-Kitahara A; Yonemoto G; Koro L; Ikezu S; Ikezu T
    J Biol Chem; 2017 Jun; 292(25):10651-10663. PubMed ID: 28490631
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer's disease.
    Dhandapani R; Neri M; Bernhard M; Brzak I; Schweizer T; Rudin S; Joller S; Berth R; Kernen J; Neuhaus A; Waldt A; Cuttat R; Naumann U; Keller CG; Roma G; Feuerbach D; Shimshek DR; Neumann U; Gasparini F; Galimberti I
    Cell Rep; 2022 May; 39(9):110883. PubMed ID: 35649351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the
    Shi Q; Chang C; Saliba A; Bhat MA
    J Neurosci; 2022 Jul; 42(27):5294-5313. PubMed ID: 35672148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway.
    Zheng H; Jia L; Liu CC; Rong Z; Zhong L; Yang L; Chen XF; Fryer JD; Wang X; Zhang YW; Xu H; Bu G
    J Neurosci; 2017 Feb; 37(7):1772-1784. PubMed ID: 28077724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
    Ellwanger DC; Wang S; Brioschi S; Shao Z; Green L; Case R; Yoo D; Weishuhn D; Rathanaswami P; Bradley J; Rao S; Cha D; Luan P; Sambashivan S; Gilfillan S; Hasson SA; Foltz IN; van Lookeren Campagne M; Colonna M
    Proc Natl Acad Sci U S A; 2021 Jan; 118(3):. PubMed ID: 33446504
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vps35-dependent recycling of Trem2 regulates microglial function.
    Yin J; Liu X; He Q; Zhou L; Yuan Z; Zhao S
    Traffic; 2016 Dec; 17(12):1286-1296. PubMed ID: 27717139
    [TBL] [Abstract][Full Text] [Related]  

  • 16. What happens to microglial TREM2 in Alzheimer's disease: Immunoregulatory turned into immunopathogenic?
    Lue LF; Schmitz C; Walker DG
    Neuroscience; 2015 Aug; 302():138-50. PubMed ID: 25281879
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TREM2, microglia, and Alzheimer's disease.
    Qin Q; Teng Z; Liu C; Li Q; Yin Y; Tang Y
    Mech Ageing Dev; 2021 Apr; 195():111438. PubMed ID: 33516818
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia.
    Piers TM; Cosker K; Mallach A; Johnson GT; Guerreiro R; Hardy J; Pocock JM
    FASEB J; 2020 Feb; 34(2):2436-2450. PubMed ID: 31907987
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease.
    Schlepckow K; Morenas-Rodríguez E; Hong S; Haass C
    Lancet Neurol; 2023 Nov; 22(11):1048-1060. PubMed ID: 37863592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. γ-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics.
    Steiner A; Schlepckow K; Brunner B; Steiner H; Haass C; Hagn F
    EMBO J; 2020 Oct; 39(20):e104247. PubMed ID: 32830336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.