147 related articles for article (PubMed ID: 37247564)
1. Inhibitors of UHRF1 base flipping activity showing cytotoxicity against cancer cells.
Ciaco S; Mazzoleni V; Javed A; Eiler S; Ruff M; Mousli M; Mori M; Mély Y
Bioorg Chem; 2023 Aug; 137():106616. PubMed ID: 37247564
[TBL] [Abstract][Full Text] [Related]
2. The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation.
Vaughan RM; Rothbart SB; Dickson BM
J Biol Chem; 2019 Oct; 294(43):15724-15732. PubMed ID: 31481468
[TBL] [Abstract][Full Text] [Related]
3. Dynamics of Methylated Cytosine Flipping by UHRF1.
Kilin V; Gavvala K; Barthes NP; Michel BY; Shin D; Boudier C; Mauffret O; Yashchuk V; Mousli M; Ruff M; Granger F; Eiler S; Bronner C; Tor Y; Burger A; Mély Y
J Am Chem Soc; 2017 Feb; 139(6):2520-2528. PubMed ID: 28112929
[TBL] [Abstract][Full Text] [Related]
4. A Molecular Tool Targeting the Base-Flipping Activity of Human UHRF1.
Zaayter L; Mori M; Ahmad T; Ashraf W; Boudier C; Kilin V; Gavvala K; Richert L; Eiler S; Ruff M; Botta M; Bronner C; Mousli M; Mély Y
Chemistry; 2019 Oct; 25(58):13363-13375. PubMed ID: 31322780
[TBL] [Abstract][Full Text] [Related]
5. Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation.
Myrianthopoulos V; Cartron PF; Liutkevičiūtė Z; Klimašauskas S; Matulis D; Bronner C; Martinet N; Mikros E
Eur J Med Chem; 2016 May; 114():390-6. PubMed ID: 27049577
[TBL] [Abstract][Full Text] [Related]
6. Structure-based screening of chemical libraries to identify small molecules that are likely to bind with the SET and RING-associated (SRA) domain of Ubiquitin-like, PHD and Ring Finger-containing 1 (UHRF1).
Patnaik D
BMC Res Notes; 2020 May; 13(1):254. PubMed ID: 32448288
[TBL] [Abstract][Full Text] [Related]
7. Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1.
Kori S; Shibahashi Y; Ekimoto T; Nishiyama A; Yoshimi S; Yamaguchi K; Nagatoishi S; Ohta M; Tsumoto K; Nakanishi M; Defossez PA; Ikeguchi M; Arita K
Bioorg Med Chem; 2021 Dec; 52():116500. PubMed ID: 34801826
[TBL] [Abstract][Full Text] [Related]
8. The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.
Bashtrykov P; Jankevicius G; Jurkowska RZ; Ragozin S; Jeltsch A
J Biol Chem; 2014 Feb; 289(7):4106-15. PubMed ID: 24368767
[TBL] [Abstract][Full Text] [Related]
9. Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain.
Polepalli S; George SM; Valli Sri Vidya R; Rodrigues GS; Ramachandra L; Chandrashekar R; M DN; Rao PPN; Pestell RG; Rao M
Int J Biochem Cell Biol; 2019 Sep; 114():105558. PubMed ID: 31238111
[TBL] [Abstract][Full Text] [Related]
10. The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence.
Jung HJ; Byun HO; Jee BA; Min S; Jeoun UW; Lee YK; Seo Y; Woo HG; Yoon G
J Biol Chem; 2017 Mar; 292(9):3729-3739. PubMed ID: 28100769
[TBL] [Abstract][Full Text] [Related]
11. Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein.
Cheng J; Yang Y; Fang J; Xiao J; Zhu T; Chen F; Wang P; Li Z; Yang H; Xu Y
J Biol Chem; 2013 Jan; 288(2):1329-39. PubMed ID: 23161542
[TBL] [Abstract][Full Text] [Related]
12. The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.
Hashimoto H; Horton JR; Zhang X; Bostick M; Jacobsen SE; Cheng X
Nature; 2008 Oct; 455(7214):826-9. PubMed ID: 18772888
[TBL] [Abstract][Full Text] [Related]
13. Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties.
Alhosin M; Sharif T; Mousli M; Etienne-Selloum N; Fuhrmann G; Schini-Kerth VB; Bronner C
J Exp Clin Cancer Res; 2011 Apr; 30(1):41. PubMed ID: 21496237
[TBL] [Abstract][Full Text] [Related]
14. Screening inhibitors for blocking UHRF1-methylated DNA interaction with capillary electrophoresis.
Lou C; Ye X; Chen G; Zhu J; Kang J
J Chromatogr A; 2021 Jan; 1636():461790. PubMed ID: 33340746
[TBL] [Abstract][Full Text] [Related]
15. Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1.
Du W; Dong Q; Zhang Z; Liu B; Zhou T; Xu RM; Wang H; Zhu B; Li Y
J Biol Chem; 2019 May; 294(22):8907-8917. PubMed ID: 31018966
[No Abstract] [Full Text] [Related]
16. Structure and hemimethylated CpG binding of the SRA domain from human UHRF1.
Qian C; Li S; Jakoncic J; Zeng L; Walsh MJ; Zhou MM
J Biol Chem; 2008 Dec; 283(50):34490-4. PubMed ID: 18945682
[TBL] [Abstract][Full Text] [Related]
17. The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
Vaughan RM; Kupai A; Foley CA; Sagum CA; Tibben BM; Eden HE; Tiedemann RL; Berryhill CA; Patel V; Shaw KM; Krajewski K; Strahl BD; Bedford MT; Frye SV; Dickson BM; Rothbart SB
Epigenetics Chromatin; 2020 Oct; 13(1):44. PubMed ID: 33097091
[TBL] [Abstract][Full Text] [Related]
18. UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
Bostick M; Kim JK; Estève PO; Clark A; Pradhan S; Jacobsen SE
Science; 2007 Sep; 317(5845):1760-4. PubMed ID: 17673620
[TBL] [Abstract][Full Text] [Related]
19. UHRF1 Induces Methylation of the
Kim MJ; Lee HJ; Choi MY; Kang SS; Kim YS; Shin JK; Choi WS
Mol Cells; 2021 Mar; 44(3):146-159. PubMed ID: 33795533
[TBL] [Abstract][Full Text] [Related]
20. Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.
Yamaguchi K; Chen X; Rodgers B; Miura F; Bashtrykov P; Bonhomme F; Salinas-Luypaert C; Haxholli D; Gutekunst N; Aygenli BÖ; Ferry L; Kirsh O; Laisné M; Scelfo A; Ugur E; Arimondo PB; Leonhardt H; Kanemaki MT; Bartke T; Fachinetti D; Jeltsch A; Ito T; Defossez PA
Nat Commun; 2024 Apr; 15(1):2960. PubMed ID: 38580649
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
