BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 37247931)

  • 21. Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
    Nishikubo K; Ohgaki R; Liu X; Okanishi H; Xu M; Endou H; Kanai Y
    Cancer Cell Int; 2023 Jun; 23(1):116. PubMed ID: 37322479
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis.
    Markowicz-Piasecka M; Huttunen J; Montaser A; Huttunen KM
    Apoptosis; 2020 Jun; 25(5-6):426-440. PubMed ID: 32405891
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models.
    Shi Z; Kaneda-Nakashima K; Ohgaki R; Xu M; Okanishi H; Endou H; Nagamori S; Kanai Y
    Sci Rep; 2023 Aug; 13(1):13943. PubMed ID: 37626086
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
    Caumanns JJ; Berns K; Wisman GBA; Fehrmann RSN; Tomar T; Klip H; Meersma GJ; Hijmans EM; Gennissen AMC; Duiker EW; Weening D; Itamochi H; Kluin RJC; Reyners AKL; Birrer MJ; Salvesen HB; Vergote I; van Nieuwenhuysen E; Brenton J; Braicu EI; Kupryjanczyk J; Spiewankiewicz B; Mittempergher L; Bernards R; van der Zee AGJ; de Jong S
    Clin Cancer Res; 2018 Aug; 24(16):3928-3940. PubMed ID: 29685880
    [No Abstract]   [Full Text] [Related]  

  • 25. Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma.
    Bixel K; Saini U; Kumar Bid H; Fowler J; Riley M; Wanner R; Deepa Priya Dorayappan K; Rajendran S; Konishi I; Matsumura N; Cohn DE; Selvendiran K
    Int J Cancer; 2017 Nov; 141(9):1856-1866. PubMed ID: 28646535
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibition of PI3K/AKT/mTOR and MAPK signaling pathways decreases progranulin expression in ovarian clear cell carcinoma (OCCC) cell line: a potential biomarker for therapy response to signaling pathway inhibitors.
    Perez-Juarez CE; Arechavaleta-Velasco F; Zeferino-Toquero M; Alvarez-Arellano L; Estrada-Moscoso I; Diaz-Cueto L
    Med Oncol; 2019 Nov; 37(1):4. PubMed ID: 31713081
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting an autocrine IL-6-SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma.
    Mehner C; Miller E; Hockla A; Coban M; Weroha SJ; Radisky DC; Radisky ES
    Oncogene; 2020 Oct; 39(42):6606-6618. PubMed ID: 32929152
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The LAT1 inhibitor JPH203 suppresses the growth of castration-resistant prostate cancer through a CD24-mediated mechanism.
    Saito S; Ando K; Sakamoto S; Xu M; Yamada Y; Rii J; Kanaoka S; Wei J; Zhao X; Pae S; Kanesaka M; Goto Y; Sazuka T; Imamura Y; Reien Y; Hamaguchi-Suzuki N; Saito S; Hirayama Y; Hashimoto H; Kanai Y; Ichikawa T; Anzai N
    Cancer Sci; 2024 Apr; ():. PubMed ID: 38655663
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C.
    Kolendowski B; Valdes YR; Hirte H; Itamochi H; Lee W; Carey M; Shepherd TG; DiMattia GE
    Cells; 2020 Nov; 9(11):. PubMed ID: 33153119
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells.
    Ma Y; Okuda S; Okanishi H; Xu M; Jin C; Endou H; Ohgaki R; Kanai Y
    J Pharmacol Sci; 2024 May; 155(1):14-20. PubMed ID: 38553134
    [TBL] [Abstract][Full Text] [Related]  

  • 31. An evaluation of progression free survival and overall survival of ovarian cancer patients with clear cell carcinoma versus serous carcinoma treated with platinum therapy: An NRG Oncology/Gynecologic Oncology Group experience.
    Oliver KE; Brady WE; Birrer M; Gershenson DM; Fleming G; Copeland LJ; Tewari K; Argenta PA; Mannel RS; Secord AA; Stephan JM; Mutch DG; Stehman FB; Muggia FM; Rose PG; Armstrong DK; Bookman MA; Burger RA; Farley JH
    Gynecol Oncol; 2017 Nov; 147(2):243-249. PubMed ID: 28807367
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells.
    Kobayashi K; Ohnishi A; Promsuk J; Shimizu S; Kanai Y; Shiokawa Y; Nagane M
    Neurosurgery; 2008 Feb; 62(2):493-503; discussion 503-4. PubMed ID: 18382329
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Targeted Suppression and Knockout of ASCT2 or LAT1 in Epithelial and Mesenchymal Human Liver Cancer Cells Fail to Inhibit Growth.
    Bothwell PJ; Kron CD; Wittke EF; Czerniak BN; Bode BP
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30029480
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma.
    Higuchi K; Sakamoto S; Ando K; Maimaiti M; Takeshita N; Okunushi K; Reien Y; Imamura Y; Sazuka T; Nakamura K; Matsushima J; Furihata T; Ikehara Y; Ichikawa T; Anzai N
    Sci Rep; 2019 Nov; 9(1):16776. PubMed ID: 31748583
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
    Quan L; Ohgaki R; Hara S; Okuda S; Wei L; Okanishi H; Nagamori S; Endou H; Kanai Y
    J Exp Clin Cancer Res; 2020 Nov; 39(1):266. PubMed ID: 33256804
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer Cells.
    Xu M; Sakamoto S; Matsushima J; Kimura T; Ueda T; Mizokami A; Kanai Y; Ichikawa T
    J Urol; 2016 May; 195(5):1588-1597. PubMed ID: 26682754
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Relationship between LAT1 expression and response to platinum-based chemotherapy in non-small cell lung cancer patients with postoperative recurrence.
    Kaira K; Takahashi T; Murakami H; Shukuya T; Kenmotsu H; Naito T; Oriuchi N; Kanai Y; Endo M; Kondo H; Nakajima T; Yamamoto N
    Anticancer Res; 2011 Nov; 31(11):3775-82. PubMed ID: 22110199
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor.
    Okanishi H; Ohgaki R; Okuda S; Endou H; Kanai Y
    Cancer Sci; 2021 Feb; 112(2):871-883. PubMed ID: 33264461
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
    Shindo H; Harada-Shoji N; Ebata A; Sato M; Soga T; Miyashita M; Tada H; Kawai M; Kosaka S; Onuki K; Usami S; Furumoto S; Hayashi S; Abe T; Suzuki T; Ishida T; Sasano H
    Cancers (Basel); 2021 Aug; 13(17):. PubMed ID: 34503187
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma.
    Okamoto T; Mandai M; Matsumura N; Yamaguchi K; Kondoh H; Amano Y; Baba T; Hamanishi J; Abiko K; Kosaka K; Murphy SK; Mori S; Konishi I
    Mol Carcinog; 2015 Jan; 54(1):35-49. PubMed ID: 24105991
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.