These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 37257821)

  • 1. Aβ43 levels determine the onset of pathological amyloid deposition.
    Tambini MD; Yin T; Yesiltepe M; Breuillaud L; Zehntner SP; d'Abramo C; Giliberto L; D'Adamio L
    J Biol Chem; 2023 Jul; 299(7):104868. PubMed ID: 37257821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Knock-in rats with homozygous
    Tambini MD; D'Adamio L
    J Biol Chem; 2020 May; 295(21):7442-7451. PubMed ID: 32265300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer's disease.
    Serneels L; T'Syen D; Perez-Benito L; Theys T; Holt MG; De Strooper B
    Mol Neurodegener; 2020 Oct; 15(1):60. PubMed ID: 33076948
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations.
    Pimenova AA; Goate AM
    Neurobiol Dis; 2020 May; 138():104785. PubMed ID: 32032730
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau.
    Guo Q; Li H; Cole AL; Hur JY; Li Y; Zheng H
    PLoS One; 2013; 8(11):e80706. PubMed ID: 24278307
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of Non-Amyloidogenic Mutations in APP Supports Loss of Function Hypothesis of Alzheimer's Disease.
    Kim M; Bezprozvanny I
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity.
    Schilling S; Pradhan A; Heesch A; Helbig A; Blennow K; Koch C; Bertgen L; Koo EH; Brinkmalm G; Zetterberg H; Kins S; Eggert S
    Acta Neuropathol Commun; 2023 Jun; 11(1):87. PubMed ID: 37259128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cortical neurodegeneration caused by
    Yan K; Zhang C; Kang J; Montenegro P; Shen J
    Proc Natl Acad Sci U S A; 2024 Aug; 121(34):e2409343121. PubMed ID: 39136994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aβ profiles generated by Alzheimer's disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset.
    Petit D; Fernández SG; Zoltowska KM; Enzlein T; Ryan NS; O'Connor A; Szaruga M; Hill E; Vandenberghe R; Fox NC; Chávez-Gutiérrez L
    Mol Psychiatry; 2022 Jun; 27(6):2821-2832. PubMed ID: 35365805
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PS1 Affects the Pathology of Alzheimer's Disease by Regulating BACE1 Distribution in the ER and BACE1 Maturation in the Golgi Apparatus.
    Li N; Qiu Y; Wang H; Zhao J; Qing H
    Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production.
    Gerber H; Wu F; Dimitrov M; Garcia Osuna GM; Fraering PC
    J Biol Chem; 2017 Mar; 292(9):3751-3767. PubMed ID: 28096459
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease.
    Baranello RJ; Bharani KL; Padmaraju V; Chopra N; Lahiri DK; Greig NH; Pappolla MA; Sambamurti K
    Curr Alzheimer Res; 2015; 12(1):32-46. PubMed ID: 25523424
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Switched Aβ43 generation in familial Alzheimer's disease with presenilin 1 mutation.
    Kakuda N; Takami M; Okochi M; Kasuga K; Ihara Y; Ikeuchi T
    Transl Psychiatry; 2021 Nov; 11(1):558. PubMed ID: 34728605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta.
    Arber C; Toombs J; Lovejoy C; Ryan NS; Paterson RW; Willumsen N; Gkanatsiou E; Portelius E; Blennow K; Heslegrave A; Schott JM; Hardy J; Lashley T; Fox NC; Zetterberg H; Wray S
    Mol Psychiatry; 2020 Nov; 25(11):2919-2931. PubMed ID: 30980041
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology.
    Cai Y; Zhang XM; Macklin LN; Cai H; Luo XG; Oddo S; Laferla FM; Struble RG; Rose GM; Patrylo PR; Yan XX
    Neurotox Res; 2012 Feb; 21(2):160-74. PubMed ID: 21725719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence For and Against a Pathogenic Role of Reduced γ-Secretase Activity in Familial Alzheimer's Disease.
    Jayne T; Newman M; Verdile G; Sutherland G; Münch G; Musgrave I; Moussavi Nik SH; Lardelli M
    J Alzheimers Dis; 2016 Apr; 52(3):781-99. PubMed ID: 27060961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide.
    Sato K; Watamura N; Fujioka R; Mihira N; Sekiguchi M; Nagata K; Ohshima T; Saito T; Saido TC; Sasaguri H
    J Biol Chem; 2021 Sep; 297(3):101004. PubMed ID: 34329683
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
    Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
    J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
    Steiner H; Capell A; Leimer U; Haass C
    Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-beta protein precursor generated by beta-secretase cleavage.
    Zhang C; Browne A; Kim DY; Tanzi RE
    Curr Alzheimer Res; 2010 Feb; 7(1):21-6. PubMed ID: 20205669
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.