BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 37258552)

  • 1. Cryo-EM structure of the folded-back state of human β-cardiac myosin.
    Grinzato A; Auguin D; Kikuti C; Nandwani N; Moussaoui D; Pathak D; Kandiah E; Ruppel KM; Spudich JA; Houdusse A; Robert-Paganin J
    Nat Commun; 2023 May; 14(1):3166. PubMed ID: 37258552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cryo-EM structure of the folded-back state of human β-cardiac myosin.
    Grinzato A; Auguin D; Kikuti C; Nandwani N; Moussaoui D; Pathak D; Kandiah E; Ruppel KM; Spudich JA; Houdusse A; Robert-Paganin J
    bioRxiv; 2023 Apr; ():. PubMed ID: 37131793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting-heads motif and super-relaxed state of myosin.
    Rasicci DV; Tiwari P; Bodt SML; Desetty R; Sadler FR; Sivaramakrishnan S; Craig R; Yengo CM
    Elife; 2022 Nov; 11():. PubMed ID: 36422472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity.
    Adhikari AS; Trivedi DV; Sarkar SS; Song D; Kooiker KB; Bernstein D; Spudich JA; Ruppel KM
    Nat Commun; 2019 Jun; 10(1):2685. PubMed ID: 31213605
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.
    Alamo L; Ware JS; Pinto A; Gillilan RE; Seidman JG; Seidman CE; Padrón R
    Elife; 2017 Jun; 6():. PubMed ID: 28606303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tail length and E525K dilated cardiomyopathy mutant alter human β-cardiac myosin super-relaxed state.
    Duno-Miranda S; Nelson SR; Rasicci DV; Bodt SML; Cirilo JA; Vang D; Sivaramakrishnan S; Yengo CM; Warshaw DM
    J Gen Physiol; 2024 Jun; 156(6):. PubMed ID: 38709176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations.
    Spudich JA
    Pflugers Arch; 2019 May; 471(5):701-717. PubMed ID: 30767072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers.
    Anderson RL; Trivedi DV; Sarkar SS; Henze M; Ma W; Gong H; Rogers CS; Gorham JM; Wong FL; Morck MM; Seidman JG; Ruppel KM; Irving TC; Cooke R; Green EM; Spudich JA
    Proc Natl Acad Sci U S A; 2018 Aug; 115(35):E8143-E8152. PubMed ID: 30104387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct detection of the myosin super-relaxed state and interacting-heads motif in solution.
    Chu S; Muretta JM; Thomas DD
    J Biol Chem; 2021 Oct; 297(4):101157. PubMed ID: 34481842
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically.
    Nandwani N; Bhowmik D; Childers MC; Goluguri RR; Dawood A; Regnier M; Spudich JA; Ruppel KM
    bioRxiv; 2024 Mar; ():. PubMed ID: 38464145
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state.
    Vander Roest AS; Liu C; Morck MM; Kooiker KB; Jung G; Song D; Dawood A; Jhingran A; Pardon G; Ranjbarvaziri S; Fajardo G; Zhao M; Campbell KS; Pruitt BL; Spudich JA; Ruppel KM; Bernstein D
    Proc Natl Acad Sci U S A; 2021 Jun; 118(24):. PubMed ID: 34117120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
    Alamo L; Qi D; Wriggers W; Pinto A; Zhu J; Bilbao A; Gillilan RE; Hu S; Padrón R
    J Mol Biol; 2016 Mar; 428(6):1142-1164. PubMed ID: 26851071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States.
    Gollapudi SK; Ma W; Chakravarthy S; Combs AC; Sa N; Langer S; Irving TC; Nag S
    J Mol Biol; 2021 Nov; 433(23):167295. PubMed ID: 34627791
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin.
    Sarkar SS; Trivedi DV; Morck MM; Adhikari AS; Pasha SN; Ruppel KM; Spudich JA
    Sci Adv; 2020 Apr; 6(14):eaax0069. PubMed ID: 32284968
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biophysical properties of human β-cardiac myosin with converter mutations that cause hypertrophic cardiomyopathy.
    Kawana M; Sarkar SS; Sutton S; Ruppel KM; Spudich JA
    Sci Adv; 2017 Feb; 3(2):e1601959. PubMed ID: 28246639
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties.
    Vera CD; Johnson CA; Walklate J; Adhikari A; Svicevic M; Mijailovich SM; Combs AC; Langer SJ; Ruppel KM; Spudich JA; Geeves MA; Leinwand LA
    J Biol Chem; 2019 Nov; 294(46):17451-17462. PubMed ID: 31582565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light.
    Trivedi DV; Adhikari AS; Sarkar SS; Ruppel KM; Spudich JA
    Biophys Rev; 2018 Feb; 10(1):27-48. PubMed ID: 28717924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations.
    Nag S; Trivedi DV; Sarkar SS; Adhikari AS; Sunitha MS; Sutton S; Ruppel KM; Spudich JA
    Nat Struct Mol Biol; 2017 Jun; 24(6):525-533. PubMed ID: 28481356
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lessons from a tarantula: new insights into myosin interacting-heads motif evolution and its implications on disease.
    Alamo L; Pinto A; Sulbarán G; Mavárez J; Padrón R
    Biophys Rev; 2018 Oct; 10(5):1465-1477. PubMed ID: 28871552
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Variants of the myosin interacting-heads motif.
    Padrón R; Dutta D; Craig R
    J Gen Physiol; 2023 Jan; 155(1):. PubMed ID: 36346431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.