BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 37260014)

  • 1. Disease mutations and phosphorylation alter the allosteric pathways involved in autoinhibition of protein phosphatase 2A.
    Konovalov KA; Wu CG; Qiu Y; Balakrishnan VK; Parihar PS; O'Connor MS; Xing Y; Huang X
    J Chem Phys; 2023 Jun; 158(21):. PubMed ID: 37260014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. β-Adrenergic regulation of cardiac type 2A protein phosphatase through phosphorylation of regulatory subunit B56δ at S573.
    Ranieri A; Kemp E; Burgoyne JR; Avkiran M
    J Mol Cell Cardiol; 2018 Feb; 115():20-31. PubMed ID: 29294329
    [TBL] [Abstract][Full Text] [Related]  

  • 3. B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability.
    Houge G; Haesen D; Vissers LE; Mehta S; Parker MJ; Wright M; Vogt J; McKee S; Tolmie JL; Cordeiro N; Kleefstra T; Willemsen MH; Reijnders MR; Berland S; Hayman E; Lahat E; Brilstra EH; van Gassen KL; Zonneveld-Huijssoon E; de Bie CI; Hoischen A; Eichler EE; Holdhus R; Steen VM; Døskeland SO; Hurles ME; FitzPatrick DR; Janssens V
    J Clin Invest; 2015 Aug; 125(8):3051-62. PubMed ID: 26168268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
    Wu CG; Balakrishnan VK; Merrill RA; Parihar PS; Konovolov K; Chen YC; Xu Z; Wei H; Sundaresan R; Cui Q; Wadzinski BE; Swingle MR; Musiyenko A; Chung WK; Honkanen RE; Suzuki A; Huang X; Strack S; Xing Y
    Proc Natl Acad Sci U S A; 2024 Jan; 121(1):e2310727120. PubMed ID: 38150499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme.
    Wu CG; Balakrishnan VK; Parihar PS; Konovolov K; Chen YC; Merrill RA; Wei H; Carragher B; Sundaresan R; Cui Q; Wadzinski BE; Swingle MR; Musiyenko A; Honkanen R; Chung WK; Suzuki A; Strack S; Huang X; Xing Y
    bioRxiv; 2023 Apr; ():. PubMed ID: 37066309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.
    Dodge-Kafka KL; Bauman A; Mayer N; Henson E; Heredia L; Ahn J; McAvoy T; Nairn AC; Kapiloff MS
    J Biol Chem; 2010 Apr; 285(15):11078-86. PubMed ID: 20106966
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein kinase C-dependent dephosphorylation of tyrosine hydroxylase requires the B56δ heterotrimeric form of protein phosphatase 2A.
    Ahn JH; Kim Y; Kim HS; Greengard P; Nairn AC
    PLoS One; 2011; 6(10):e26292. PubMed ID: 22046270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit.
    Ahn JH; McAvoy T; Rakhilin SV; Nishi A; Greengard P; Nairn AC
    Proc Natl Acad Sci U S A; 2007 Feb; 104(8):2979-84. PubMed ID: 17301223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allosteric Autoinhibition Pathway in Transcription Factor ERG: Dynamics Network and Mutant Experimental Evaluations.
    Ye W; Qian T; Liu H; Luo R; Chen HF
    J Chem Inf Model; 2017 May; 57(5):1153-1165. PubMed ID: 28425706
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation on the PPP2R5D B regulatory subunit modulates the biochemical properties of protein phosphatase 2A.
    Yu UY; Ahn JH
    BMB Rep; 2010 Apr; 43(4):263-7. PubMed ID: 20423611
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3.
    Gordon J; Hwang J; Carrier KJ; Jones CA; Kern QL; Moreno CS; Karas RH; Pallas DC
    BMC Biochem; 2011 Oct; 12():54. PubMed ID: 21985334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure- and modeling-based identification of the adenovirus E4orf4 binding site in the protein phosphatase 2A B55α subunit.
    Horowitz B; Sharf R; Avital-Shacham M; Pechkovsky A; Kleinberger T
    J Biol Chem; 2013 May; 288(19):13718-27. PubMed ID: 23530045
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades.
    Smolen KA; Papke CM; Swingle MR; Musiyenko A; Li C; Salter EA; Camp AD; Honkanen RE; Kettenbach AN
    J Biol Chem; 2023 Sep; 299(9):105154. PubMed ID: 37572851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular determinants for PP2A substrate specificity: charged residues mediate dephosphorylation of tyrosine hydroxylase by the PP2A/B' regulatory subunit.
    Saraf A; Oberg EA; Strack S
    Biochemistry; 2010 Feb; 49(5):986-95. PubMed ID: 20017541
    [TBL] [Abstract][Full Text] [Related]  

  • 15. I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A.
    Chen S; Li B; Grundke-Iqbal I; Iqbal K
    J Biol Chem; 2008 Apr; 283(16):10513-21. PubMed ID: 18245083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase.
    Hertz EPT; Kruse T; Davey NE; López-Méndez B; Sigurðsson JO; Montoya G; Olsen JV; Nilsson J
    Mol Cell; 2016 Aug; 63(4):686-695. PubMed ID: 27453045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. VIP1, a bZIP protein, interacts with the catalytic subunit of protein phosphatase 2A in Arabidopsis thaliana.
    Yoon HS; Fujino K; Liu S; Takano T; Tsugama D
    Plant Signal Behav; 2020; 15(2):1706026. PubMed ID: 31861962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity.
    Low IC; Loh T; Huang Y; Virshup DM; Pervaiz S
    Blood; 2014 Oct; 124(14):2223-34. PubMed ID: 25082878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cooperative mechanics of PR65 scaffold underlies the allosteric regulation of the phosphatase PP2A.
    Kaynak BT; Dahmani ZL; Doruker P; Banerjee A; Yang SH; Gordon R; Itzhaki LS; Bahar I
    Structure; 2023 May; 31(5):607-618.e3. PubMed ID: 36948205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. B56γ tumor-associated mutations provide new mechanisms for B56γ-PP2A tumor suppressor activity.
    Nobumori Y; Shouse GP; Wu Y; Lee KJ; Shen B; Liu X
    Mol Cancer Res; 2013 Sep; 11(9):995-1003. PubMed ID: 23723076
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.