BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 37267517)

  • 1. PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma.
    Sloan SL; Brown F; Long M; Weigel C; Koirala S; Chung JH; Pray B; Villagomez L; Hinterschied C; Sircar A; Helmig-Mason J; Prouty A; Brooks E; Youssef Y; Hanel W; Parekh S; Chan WK; Chen Z; Lapalombella R; Sehgal L; Vaddi K; Scherle P; Chen-Kiang S; Di Liberto M; Elemento O; Meydan C; Foox J; Butler D; Mason CE; Baiocchi RA; Alinari L
    Blood; 2023 Sep; 142(10):887-902. PubMed ID: 37267517
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Resistance to PRMT5-targeted therapy in mantle cell lymphoma.
    Long ME; Koirala S; Sloan S; Brown-Burke F; Weigel C; Villagomez L; Corps K; Sharma A; Hout I; Harper M; Helmig-Mason J; Tallada S; Chen Z; Scherle P; Vaddi K; Chen-Kiang S; Di Liberto M; Meydan C; Foox J; Butler D; Mason C; Alinari L; Blaser BW; Baiocchi R
    Blood Adv; 2024 Jan; 8(1):150-163. PubMed ID: 37782774
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma.
    Brown-Burke F; Hwang I; Sloan S; Hinterschied C; Helmig-Mason J; Long M; Chan WK; Prouty A; Chung JH; Zhang Y; Singh S; Youssef Y; Bhagwat N; Chen Z; Chen-Kiang S; Di Liberto M; Elemento O; Sehgal L; Alinari L; Vaddi K; Scherle P; Lapalombella R; Paik J; Baiocchi RA
    Blood Adv; 2023 Oct; 7(20):6211-6224. PubMed ID: 37327122
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploiting PRMT5 as a target for combination therapy in mantle cell lymphoma characterized by frequent ATM and TP53 mutations.
    Che Y; Liu Y; Yao Y; Hill HA; Li Y; Cai Q; Yan F; Jain P; Wang W; Rui L; Wang M
    Blood Cancer J; 2023 Feb; 13(1):27. PubMed ID: 36797243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
    Chan-Penebre E; Kuplast KG; Majer CR; Boriack-Sjodin PA; Wigle TJ; Johnston LD; Rioux N; Munchhof MJ; Jin L; Jacques SL; West KA; Lingaraj T; Stickland K; Ribich SA; Raimondi A; Scott MP; Waters NJ; Pollock RM; Smith JJ; Barbash O; Pappalardi M; Ho TF; Nurse K; Oza KP; Gallagher KT; Kruger R; Moyer MP; Copeland RA; Chesworth R; Duncan KW
    Nat Chem Biol; 2015 Jun; 11(6):432-7. PubMed ID: 25915199
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/β-catenin and AKT/GSK3β proliferative signaling.
    Chung J; Karkhanis V; Baiocchi RA; Sif S
    J Biol Chem; 2019 May; 294(19):7692-7710. PubMed ID: 30885941
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression.
    Yu D; Zhang Y; Chen G; Xie Y; Xu Z; Chang S; Hu L; Li B; Bu W; Wang Y; Xiao W; Sun X; Chang G; Gao L; Qiang S; Wu X; Zhu W; Shi J
    Acta Biochim Biophys Sin (Shanghai); 2018 Aug; 50(8):782-792. PubMed ID: 29961897
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.
    Yan F; Alinari L; Lustberg ME; Martin LK; Cordero-Nieves HM; Banasavadi-Siddegowda Y; Virk S; Barnholtz-Sloan J; Bell EH; Wojton J; Jacob NK; Chakravarti A; Nowicki MO; Wu X; Lapalombella R; Datta J; Yu B; Gordon K; Haseley A; Patton JT; Smith PL; Ryu J; Zhang X; Mo X; Marcucci G; Nuovo G; Kwon CH; Byrd JC; Chiocca EA; Li C; Sif S; Jacob S; Lawler S; Kaur B; Baiocchi RA
    Cancer Res; 2014 Mar; 74(6):1752-65. PubMed ID: 24453002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance.
    Kim A; Seong KM; Kang HJ; Park S; Lee SS
    Oncotarget; 2015 Nov; 6(35):38225-38. PubMed ID: 26517678
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma.
    Pal S; Baiocchi RA; Byrd JC; Grever MR; Jacob ST; Sif S
    EMBO J; 2007 Aug; 26(15):3558-69. PubMed ID: 17627275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective PRMT5 Inhibitors Suppress Human CD8
    Strobl CD; Schaffer S; Haug T; Völkl S; Peter K; Singer K; Böttcher M; Mougiakakos D; Mackensen A; Aigner M
    Mol Cancer Ther; 2020 Feb; 19(2):409-419. PubMed ID: 31712395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.
    Alinari L; Mahasenan KV; Yan F; Karkhanis V; Chung JH; Smith EM; Quinion C; Smith PL; Kim L; Patton JT; Lapalombella R; Yu B; Wu Y; Roy S; De Leo A; Pileri S; Agostinelli C; Ayers L; Bradner JE; Chen-Kiang S; Elemento O; Motiwala T; Majumder S; Byrd JC; Jacob S; Sif S; Li C; Baiocchi RA
    Blood; 2015 Apr; 125(16):2530-43. PubMed ID: 25742700
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.
    Chiron D; Di Liberto M; Martin P; Huang X; Sharman J; Blecua P; Mathew S; Vijay P; Eng K; Ali S; Johnson A; Chang B; Ely S; Elemento O; Mason CE; Leonard JP; Chen-Kiang S
    Cancer Discov; 2014 Sep; 4(9):1022-35. PubMed ID: 25082755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PRMT5 is upregulated by B-cell receptor signaling and forms a positive-feedback loop with PI3K/AKT in lymphoma cells.
    Zhu F; Guo H; Bates PD; Zhang S; Zhang H; Nomie KJ; Li Y; Lu L; Seibold KR; Wang F; Rumball I; Cameron H; Hoang NM; Yang DT; Xu W; Zhang L; Wang M; Capitini CM; Rui L
    Leukemia; 2019 Dec; 33(12):2898-2911. PubMed ID: 31123343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential PAX5 levels promote malignant B-cell infiltration, progression and drug resistance, and predict a poor prognosis in MCL patients independent of CCND1.
    Teo AE; Chen Z; Miranda RN; McDonnell T; Medeiros LJ; McCarty N
    Leukemia; 2016 Mar; 30(3):580-93. PubMed ID: 26073757
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.
    Jin L; Tabe Y; Kimura S; Zhou Y; Kuroda J; Asou H; Inaba T; Konopleva M; Andreeff M; Miida T
    Br J Cancer; 2011 Jan; 104(1):91-100. PubMed ID: 21139584
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma.
    Rosich L; Xargay-Torrent S; López-Guerra M; Campo E; Colomer D; Roué G
    Clin Cancer Res; 2012 Oct; 18(19):5278-89. PubMed ID: 22879389
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein Arginine Methyltransferase 5 (PRMT5) and the ERK1/2 & PI3K Pathways: A Case for PRMT5 Inhibition and Combination Therapies in Cancer.
    Sapir T; Shifteh D; Pahmer M; Goel S; Maitra R
    Mol Cancer Res; 2021 Mar; 19(3):388-394. PubMed ID: 33288733
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.
    Wei TY; Juan CC; Hisa JY; Su LJ; Lee YC; Chou HY; Chen JM; Wu YC; Chiu SC; Hsu CP; Liu KL; Yu CT
    Cancer Sci; 2012 Sep; 103(9):1640-50. PubMed ID: 22726390
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel targeted therapies for mantle cell lymphoma.
    Alinari L; Christian B; Baiocchi RA
    Oncotarget; 2012 Feb; 3(2):203-11. PubMed ID: 22361516
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.