199 related articles for article (PubMed ID: 37282854)
1. Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice.
Rabinowitsch AI; Maretzky T; Weskamp G; Haxaire C; Tueshaus J; Lichtenthaler SF; Monette S; Blobel CP
J Cell Sci; 2023 Jul; 136(13):. PubMed ID: 37282854
[TBL] [Abstract][Full Text] [Related]
2. Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity.
Bläsius K; Ludwig L; Knapp S; Flaßhove C; Sonnabend F; Keller D; Tacken N; Gao X; Kahveci-Türköz S; Grannemann C; Babendreyer A; Adrain C; Huth S; Baron JM; Ludwig A; Düsterhöft S
Cell Mol Life Sci; 2024 Feb; 81(1):102. PubMed ID: 38409522
[TBL] [Abstract][Full Text] [Related]
3. ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Weskamp G; Tüshaus J; Li D; Feederle R; Maretzky T; Swendemann S; Falck-Pedersen E; McIlwain DR; Mak TW; Salmon JE; Lichtenthaler SF; Blobel CP
J Biol Chem; 2020 Mar; 295(13):4350-4358. PubMed ID: 32060096
[TBL] [Abstract][Full Text] [Related]
4. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
Maney SK; McIlwain DR; Polz R; Pandyra AA; Sundaram B; Wolff D; Ohishi K; Maretzky T; Brooke MA; Evers A; Vasudevan AA; Aghaeepour N; Scheller J; Münk C; Häussinger D; Mak TW; Nolan GP; Kelsell DP; Blobel CP; Lang KS; Lang PA
Sci Signal; 2015 Nov; 8(401):ra109. PubMed ID: 26535007
[TBL] [Abstract][Full Text] [Related]
5. iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function.
Brooke MA; Etheridge SL; Kaplan N; Simpson C; O'Toole EA; Ishida-Yamamoto A; Marches O; Getsios S; Kelsell DP
Hum Mol Genet; 2014 Aug; 23(15):4064-76. PubMed ID: 24643277
[TBL] [Abstract][Full Text] [Related]
6. Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Siggs OM; Grieve A; Xu H; Bambrough P; Christova Y; Freeman M
Biol Open; 2014 Nov; 3(12):1151-7. PubMed ID: 25395669
[TBL] [Abstract][Full Text] [Related]
7. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
[TBL] [Abstract][Full Text] [Related]
8. Role of iRhoms 1 and 2 in Endochondral Ossification.
Fang R; Haxaire C; Otero M; Lessard S; Weskamp G; McIlwain DR; Mak TW; Lichtenthaler SF; Blobel CP
Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33227998
[TBL] [Abstract][Full Text] [Related]
9. ADAM17 is essential for ectodomain shedding of the EGF-receptor ligand amphiregulin.
Hosur V; Farley ML; Burzenski LM; Shultz LD; Wiles MV
FEBS Open Bio; 2018 Apr; 8(4):702-710. PubMed ID: 29632822
[TBL] [Abstract][Full Text] [Related]
10. Identification of Molecular Determinants in iRhoms1 and 2 That Contribute to the Substrate Selectivity of Stimulated ADAM17.
Zhao Y; Dávila EM; Li X; Tang B; Rabinowitsch AI; Perez-Aguilar JM; Blobel CP
Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361585
[TBL] [Abstract][Full Text] [Related]
11. Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Li X; Maretzky T; Perez-Aguilar JM; Monette S; Weskamp G; Le Gall S; Beutler B; Weinstein H; Blobel CP
J Cell Sci; 2017 Mar; 130(5):868-878. PubMed ID: 28104813
[TBL] [Abstract][Full Text] [Related]
12. The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.
Urriola-Muñoz P; Li X; Maretzky T; McIlwain DR; Mak TW; Reyes JG; Blobel CP; Moreno RD
J Cell Physiol; 2018 Mar; 233(3):2247-2256. PubMed ID: 28703301
[TBL] [Abstract][Full Text] [Related]
13. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X; Maretzky T; Weskamp G; Monette S; Qing X; Issuree PD; Crawford HC; McIlwain DR; Mak TW; Salmon JE; Blobel CP
Proc Natl Acad Sci U S A; 2015 May; 112(19):6080-5. PubMed ID: 25918388
[TBL] [Abstract][Full Text] [Related]
14. iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Maretzky T; McIlwain DR; Issuree PD; Li X; Malapeira J; Amin S; Lang PA; Mak TW; Blobel CP
Proc Natl Acad Sci U S A; 2013 Jul; 110(28):11433-8. PubMed ID: 23801765
[TBL] [Abstract][Full Text] [Related]
15. Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Hosur V; Johnson KR; Burzenski LM; Stearns TM; Maser RS; Shultz LD
Proc Natl Acad Sci U S A; 2014 May; 111(21):E2200-9. PubMed ID: 24825892
[TBL] [Abstract][Full Text] [Related]
16. Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Hosur V; Lyons BL; Burzenski LM; Shultz LD
BMC Res Notes; 2017 Nov; 10(1):573. PubMed ID: 29116018
[TBL] [Abstract][Full Text] [Related]
17. iRHOM2: A Regulator of Palmoplantar Biology, Inflammation, and Viral Susceptibility.
Chao-Chu J; Murtough S; Zaman N; Pennington DJ; Blaydon DC; Kelsell DP
J Invest Dermatol; 2021 Apr; 141(4):722-726. PubMed ID: 33080304
[TBL] [Abstract][Full Text] [Related]
18. Mechanistic insight on the role of iRhom2-TNF-α-BAFF signaling pathway in various autoimmune disorders.
Dwivedi SD; Shukla R; Yadav K; Rathor LS; Singh D; Singh MR
Adv Biol Regul; 2024 May; 92():101011. PubMed ID: 38151421
[TBL] [Abstract][Full Text] [Related]
19. iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Qing X; Rogers L; Mortha A; Lavin Y; Redecha P; Issuree PD; Maretzky T; Merad M; McIlwain D; Mak TW; Overall CM; Blobel CP; Salmon JE
Eur J Immunol; 2016 Dec; 46(12):2737-2748. PubMed ID: 27601030
[TBL] [Abstract][Full Text] [Related]
20. Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Lu F; Zhao H; Dai Y; Wang Y; Lee CH; Freeman M
Mol Cell; 2024 Jun; 84(11):2152-2165.e5. PubMed ID: 38781971
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
