BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 37290531)

  • 1. CovET: A covariation-evolutionary trace method that identifies protein structure-function modules.
    Konecki DM; Hamrick S; Wang C; Agosto MA; Wensel TG; Lichtarge O
    J Biol Chem; 2023 Jul; 299(7):104896. PubMed ID: 37290531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation.
    Sung YM; Wilkins AD; Rodriguez GJ; Wensel TG; Lichtarge O
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3539-44. PubMed ID: 26979958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions.
    Huh E; Agosto MA; Wensel TG; Lichtarge O
    J Biol Chem; 2023 Apr; 299(4):103030. PubMed ID: 36806686
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative analysis of sequence covariation methods to mine evolutionary hubs: examples from selected GPCR families.
    Pelé J; Moreau M; Abdi H; Rodien P; Castel H; Chabbert M
    Proteins; 2014 Sep; 82(9):2141-56. PubMed ID: 24677372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions.
    Madabushi S; Gross AK; Philippi A; Meng EC; Wensel TG; Lichtarge O
    J Biol Chem; 2004 Feb; 279(9):8126-32. PubMed ID: 14660595
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Evolutionary Trace method defines functionally important bases and sites common to RNA families.
    Novikov IB; Wilkins AD; Lichtarge O
    PLoS Comput Biol; 2020 Mar; 16(3):e1007583. PubMed ID: 32208421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of functionally important residues/domains in membrane proteins using an evolutionary approach coupled with systematic mutational analysis.
    Rajagopalan L; Pereira FA; Lichtarge O; Brownell WE
    Methods Mol Biol; 2009; 493():287-97. PubMed ID: 18839354
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An evolutionary trace method defines binding surfaces common to protein families.
    Lichtarge O; Bourne HR; Cohen FE
    J Mol Biol; 1996 Mar; 257(2):342-58. PubMed ID: 8609628
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural clusters of evolutionary trace residues are statistically significant and common in proteins.
    Madabushi S; Yao H; Marsh M; Kristensen DM; Philippi A; Sowa ME; Lichtarge O
    J Mol Biol; 2002 Feb; 316(1):139-54. PubMed ID: 11829509
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evolution of the class C GPCR Venus flytrap modules involved positive selected functional divergence.
    Cao J; Huang S; Qian J; Huang J; Jin L; Su Z; Yang J; Liu J
    BMC Evol Biol; 2009 Mar; 9():67. PubMed ID: 19323848
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Covariation Is a Poor Measure of Molecular Coevolution.
    Talavera D; Lovell SC; Whelan S
    Mol Biol Evol; 2015 Sep; 32(9):2456-68. PubMed ID: 25944916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications.
    Cvicek V; Goddard WA; Abrol R
    PLoS Comput Biol; 2016 Mar; 12(3):e1004805. PubMed ID: 27028541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. How is structural divergence related to evolutionary information?
    Zea DJ; Monzon AM; Parisi G; Marino-Buslje C
    Mol Phylogenet Evol; 2018 Oct; 127():859-866. PubMed ID: 29953938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors.
    Rodriguez GJ; Yao R; Lichtarge O; Wensel TG
    Proc Natl Acad Sci U S A; 2010 Apr; 107(17):7787-92. PubMed ID: 20385837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of covariation in an SH3 domain sequence alignment: applications in tertiary contact prediction and the design of compensating hydrophobic core substitutions.
    Larson SM; Di Nardo AA; Davidson AR
    J Mol Biol; 2000 Oct; 303(3):433-46. PubMed ID: 11031119
    [TBL] [Abstract][Full Text] [Related]  

  • 16. UET: a database of evolutionarily-predicted functional determinants of protein sequences that cluster as functional sites in protein structures.
    Lua RC; Wilson SJ; Konecki DM; Wilkins AD; Venner E; Morgan DH; Lichtarge O
    Nucleic Acids Res; 2016 Jan; 44(D1):D308-12. PubMed ID: 26590254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An indel in transmembrane helix 2 helps to trace the molecular evolution of class A G-protein-coupled receptors.
    Devillé J; Rey J; Chabbert M
    J Mol Evol; 2009 May; 68(5):475-89. PubMed ID: 19357801
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Accounting for epistatic interactions improves the functional analysis of protein structures.
    Wilkins AD; Venner E; Marciano DC; Erdin S; Atri B; Lua RC; Lichtarge O
    Bioinformatics; 2013 Nov; 29(21):2714-21. PubMed ID: 24021383
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural evolution of G-protein-coupled receptors: a sequence space approach.
    Bécu JM; Pelé J; Rodien P; Abdi H; Chabbert M
    Methods Enzymol; 2013; 520():49-66. PubMed ID: 23332695
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Detecting compensatory covariation signals in protein evolution using reconstructed ancestral sequences.
    Fukami-Kobayashi K; Schreiber DR; Benner SA
    J Mol Biol; 2002 Jun; 319(3):729-43. PubMed ID: 12054866
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.