BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 37293068)

  • 21. Ionizing radiation induces BH
    Yan T; Zhang T; Mu W; Qi Y; Guo S; Hu N; Zhao W; Zhang S; Wang Q; Shi L; Liu L
    Biochem Pharmacol; 2020 Oct; 180():114102. PubMed ID: 32562786
    [TBL] [Abstract][Full Text] [Related]  

  • 22. GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner.
    Wang Z; Zhang N; Zhang M; Jiang Y; Ng AS; Bridges E; Zhang W; Zeng X; Luo Q; Liang J; Győrffy B; Hublitz P; Liang Z; Fischer R; Kerr D; Harris AL; Cai S
    Cancer Res; 2023 Oct; 83(20):3400-3413. PubMed ID: 37463466
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Analgesia by inhibiting tetrahydrobiopterin synthesis.
    Costigan M; Latremoliere A; Woolf CJ
    Curr Opin Pharmacol; 2012 Feb; 12(1):92-9. PubMed ID: 22178186
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia.
    Belfer I; Youngblood V; Darbari DS; Wang Z; Diaw L; Freeman L; Desai K; Dizon M; Allen D; Cunnington C; Channon KM; Milton J; Hartley SW; Nolan V; Kato GJ; Steinberg MH; Goldman D; Taylor JG
    Am J Hematol; 2014 Feb; 89(2):187-93. PubMed ID: 24136375
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.
    Chu SM; Heather LC; Chuaiphichai S; Nicol T; Wright B; Miossec M; Bendall JK; Douglas G; Crabtree MJ; Channon KM
    Exp Physiol; 2023 Jun; 108(6):874-890. PubMed ID: 37184360
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
    Douglas G; Hale AB; Patel J; Chuaiphichai S; Al Haj Zen A; Rashbrook VS; Trelfa L; Crabtree MJ; McNeill E; Channon KM
    Cardiovasc Res; 2018 Aug; 114(10):1385-1399. PubMed ID: 29596571
    [TBL] [Abstract][Full Text] [Related]  

  • 27. GTP cyclohydroxylase1 (GCH1): Role in neurodegenerative diseases.
    Gupta P; Kumar R
    Gene; 2023 Dec; 888():147749. PubMed ID: 37652170
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis.
    Zhong GC; Zhao ZB; Cheng Y; Wang YB; Qiu C; Mao LH; Hu JJ; Cai D; Liu Y; Gong JP; Li SW
    Free Radic Biol Med; 2021 May; 168():81-94. PubMed ID: 33781891
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Catecholamines and Parkinson's disease: tyrosine hydroxylase (TH) over tetrahydrobiopterin (BH4) and GTP cyclohydrolase I (GCH1) to cytokines, neuromelanin, and gene therapy: a historical overview.
    Nagatsu T
    J Neural Transm (Vienna); 2023 Aug; ():. PubMed ID: 37638996
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of GTP cyclohydrolase reduces cancer pain in mice and enhances analgesic effects of morphine.
    Pickert G; Myrczek T; Rückert S; Weigert A; Häussler A; Ferreirós N; Brüne B; Lötsch J; Tegeder I
    J Mol Med (Berl); 2012 Dec; 90(12):1473-86. PubMed ID: 22706600
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
    Starr A; Sand CA; Heikal L; Kelly PD; Spina D; Crabtree M; Channon KM; Leiper JM; Nandi M
    Shock; 2014 Nov; 42(5):432-9. PubMed ID: 25046538
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity.
    Nasser A; Møller AT; Hellmund V; Thorborg SS; Jespersgaard C; Bjerrum OJ; Dupont E; Nachman G; Lykkesfeldt J; Jensen TS; Møller LB
    Pain; 2018 Jun; 159(6):1012-1024. PubMed ID: 29470312
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP.
    Ebenhoch R; Bauer M; Reinert D; Kersting A; Huber S; Schmid A; Hinz I; Feiler M; Müller K; Nar H
    J Struct Biol; 2021 Mar; 213(1):107691. PubMed ID: 33387654
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.
    Antoniades C; Cunnington C; Antonopoulos A; Neville M; Margaritis M; Demosthenous M; Bendall J; Hale A; Cerrato R; Tousoulis D; Bakogiannis C; Marinou K; Toutouza M; Vlachopoulos C; Leeson P; Stefanadis C; Karpe F; Channon KM
    Circulation; 2011 Oct; 124(17):1860-70. PubMed ID: 21969008
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
    Latremoliere A; Latini A; Andrews N; Cronin SJ; Fujita M; Gorska K; Hovius R; Romero C; Chuaiphichai S; Painter M; Miracca G; Babaniyi O; Remor AP; Duong K; Riva P; Barrett LB; Ferreirós N; Naylor A; Penninger JM; Tegeder I; Zhong J; Blagg J; Channon KM; Johnsson K; Costigan M; Woolf CJ
    Neuron; 2015 Jun; 86(6):1393-406. PubMed ID: 26087165
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.
    Ebenhoch R; Prinz S; Kaltwasser S; Mills DJ; Meinecke R; Rübbelke M; Reinert D; Bauer M; Weixler L; Zeeb M; Vonck J; Nar H
    Proc Natl Acad Sci U S A; 2020 Dec; 117(50):31838-31849. PubMed ID: 33229582
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mouse mast cells and mast cell proteases do not play a significant role in acute tissue injury pain induced by formalin.
    Magnúsdóttir EI; Grujic M; Roers A; Hartmann K; Pejler G; Lagerström MC
    Mol Pain; 2018; 14():1744806918808161. PubMed ID: 30280636
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Endothelial cell-derived tetrahydrobiopterin prevents aortic valve calcification.
    Liu Z; Dong N; Hui H; Wang Y; Liu F; Xu L; Liu M; Rao Z; Yuan Z; Shang Y; Feng J; Cai Z; Li F
    Eur Heart J; 2022 May; 43(17):1652-1664. PubMed ID: 35139535
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Implementation of a Drug Screening Platform to Target
    Cronin SJF; Davidow LS; Arvanites AC; Rubin LL; Penninger JM; Woolf CJ
    Bio Protoc; 2023 May; 13(9):e4666. PubMed ID: 37188109
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice.
    Chuaiphichai S; Dickinson Y; Whiteman CAR; Au-Yeung D; McNeill E; Channon KM; Douglas G
    Vascul Pharmacol; 2023 Jun; 150():107168. PubMed ID: 36966985
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.