These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors. Stana A; Vodnar DC; Tamaian R; Pîrnău A; Vlase L; Ionuț I; Oniga O; Tiperciuc B Int J Mol Sci; 2017 Jan; 18(1):. PubMed ID: 28106743 [TBL] [Abstract][Full Text] [Related]
3. Stepwise design, synthesis, and in vitro antifungal screening of (Z)-substituted-propenoic acid derivatives with potent broad-spectrum antifungal activity. Khedr MA Drug Des Devel Ther; 2015; 9():4501-13. PubMed ID: 26309398 [TBL] [Abstract][Full Text] [Related]
4. Molecular Docking Evaluation of Imidazole Analogues as Potent Candida albicans 14α-Demethylase Inhibitors. Rani N; Kumar P; Singh R; Sharma A Curr Comput Aided Drug Des; 2015; 11(1):8-20. PubMed ID: 26081558 [TBL] [Abstract][Full Text] [Related]
5. Molecular Modeling Studies of Halogenated Imidazoles against 14α- Demethylase from Candida Albicans for Treating Fungal Infections. Rani N; Kumar P; Singh R Infect Disord Drug Targets; 2020; 20(2):208-222. PubMed ID: 30499421 [TBL] [Abstract][Full Text] [Related]
6. Singh G Curr Drug Discov Technol; 2022; 19(6):e150622206033. PubMed ID: 35708080 [TBL] [Abstract][Full Text] [Related]
7. Synthesis, in vitro evaluation and molecular docking studies of new triazole derivatives as antifungal agents. Jiang Y; Zhang J; Cao Y; Chai X; Zou Y; Wu Q; Zhang D; Jiang Y; Sun Q Bioorg Med Chem Lett; 2011 Aug; 21(15):4471-5. PubMed ID: 21737273 [TBL] [Abstract][Full Text] [Related]
8. Small-Molecule Inhibitors Targeting Sterol 14α-Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans. Binjubair FA; Parker JE; Warrilow AG; Puri K; Braidley PJ; Tatar E; Kelly SL; Kelly DE; Simons C ChemMedChem; 2020 Jul; 15(14):1294-1309. PubMed ID: 32459374 [TBL] [Abstract][Full Text] [Related]
9. De novo design of non-coordinating indolones as potential inhibitors for lanosterol 14-α-demethylase (CYP51). González-Chávez R; Martínez R; Torre-Bouscoulet ME; Gallo M; González-Chávez MM Chem Pharm Bull (Tokyo); 2014; 62(1):16-24. PubMed ID: 24390489 [TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and evaluation of benzoheterocycle analogues as potent antifungal agents targeting CYP51. Zhao S; Wei P; Wu M; Zhang X; Zhao L; Jiang X; Hao C; Su X; Zhao D; Cheng M Bioorg Med Chem; 2018 Jul; 26(12):3242-3253. PubMed ID: 29748145 [TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and evaluation of benzotriazole derivatives as novel antifungal agents. Shah JJ; Khedkar V; Coutinho EC; Mohanraj K Bioorg Med Chem Lett; 2015 Sep; 25(17):3730-7. PubMed ID: 26117563 [TBL] [Abstract][Full Text] [Related]
12. In silico and in vitro screening to identify structurally diverse non-azole CYP51 inhibitors as potent antifungal agent. Singh A; Paliwal SK; Sharma M; Mittal A; Sharma S; Sharma JP J Mol Graph Model; 2016 Jan; 63():1-7. PubMed ID: 26579619 [TBL] [Abstract][Full Text] [Related]
13. Design, Synthesis, Bioactive Evaluation, and Molecular Dynamics Simulation of Novel 4 Bao A; Jiang W; Xie X; Wang D; Deng Z; Wang J; Li W; Tang X; Yan Y J Med Chem; 2024 May; 67(10):7954-7972. PubMed ID: 38703119 [TBL] [Abstract][Full Text] [Related]
14. In silico prediction of Antifungal compounds from Natural sources towards Lanosterol 14-alpha demethylase (CYP51) using Molecular docking and Molecular dynamic simulation. Sama-Ae I; Pattaranggoon NC; Tedasen A J Mol Graph Model; 2023 Jun; 121():108435. PubMed ID: 36848730 [TBL] [Abstract][Full Text] [Related]
15. Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase. Fouda AM; Hassan AH; Eliwa EM; Ahmed HEA; Al-Dies AM; Omar AM; Nassar HS; Halawa AH; Aljuhani N; El-Agrody AM Bioorg Chem; 2020 Dec; 105():104387. PubMed ID: 33130344 [TBL] [Abstract][Full Text] [Related]
16. Homology model, molecular dynamics simulation and novel pyrazole analogs design of Candida albicans CYP450 lanosterol 14 α-demethylase, a target enzyme for antifungal therapy. Jacob K S; Ganguly S; Kumar P; Poddar R; Kumar A J Biomol Struct Dyn; 2017 May; 35(7):1446-1463. PubMed ID: 27142238 [TBL] [Abstract][Full Text] [Related]
17. Molecular Docking and Molecular Dynamics Simulations of Synthesized Thiazole-Isatin-1,2,3-triazole Hybrids as Promising Inhibitors for DNA Gyrase and Sterol 14α-Demethylase. Kumar V; Kumari P; Yadav S; Kumari K; Jaglan S; Lal K Chem Biodivers; 2024 Oct; 21(10):e202400914. PubMed ID: 38979691 [TBL] [Abstract][Full Text] [Related]
18. The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance. Alvarez-Rueda N; Fleury A; Logé C; Pagniez F; Robert E; Morio F; Le Pape P Med Mycol; 2016 Oct; 54(7):764-775. PubMed ID: 27143634 [TBL] [Abstract][Full Text] [Related]
19. Oxidation of Isodrimeninol with PCC Yields Drimane Derivatives with Activity against Marin V; Iturra A; Opazo A; Schmidt B; Heydenreich M; Ortiz L; Jiménez VA; Paz C Biomolecules; 2020 Jul; 10(8):. PubMed ID: 32722158 [No Abstract] [Full Text] [Related]
20. Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives. Xu J; Cao Y; Zhang J; Yu S; Zou Y; Chai X; Wu Q; Zhang D; Jiang Y; Sun Q Eur J Med Chem; 2011 Jul; 46(7):3142-8. PubMed ID: 21420761 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]