212 related articles for article (PubMed ID: 37295023)
1. Anti-tumor effects of novel alkannin derivatives with potent selectivity on comprehensive analysis.
Dai ZQ; Gao F; Zhang ZJ; Lu MJ; Luo YJ; Zhang T; Shang BX; Gu YH; Zeng Q; Gao S; Guo ZQ; Xu B; Lei HM
Phytomedicine; 2023 Aug; 117():154912. PubMed ID: 37295023
[TBL] [Abstract][Full Text] [Related]
2. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2.
Chen J; Xie J; Jiang Z; Wang B; Wang Y; Hu X
Oncogene; 2011 Oct; 30(42):4297-306. PubMed ID: 21516121
[TBL] [Abstract][Full Text] [Related]
3. Apoptin Inhibits Glycolysis and Regulates Autophagy by Targeting Pyruvate Kinase M2 (PKM2) in Lung Cancer A549 Cells.
Song G; Shang C; Zhu Y; Xiu Z; Li Y; Yang X; Ge C; Han J; Jin N; Li Y; Li X; Fang J
Curr Cancer Drug Targets; 2024; 24(4):411-424. PubMed ID: 36284386
[TBL] [Abstract][Full Text] [Related]
4. Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.
Kilic-Kurt Z; Bakar-Ates F; Karakas B; Kütük Ö
Anticancer Agents Med Chem; 2018; 18(9):1303-1312. PubMed ID: 29866023
[TBL] [Abstract][Full Text] [Related]
5. Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model.
Guo W; Zhang Y; Chen T; Wang Y; Xue J; Zhang Y; Xiao W; Mo X; Lu Y
J Cancer Res Clin Oncol; 2011 Jan; 137(1):65-72. PubMed ID: 20336315
[TBL] [Abstract][Full Text] [Related]
6. PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H; Han H; Yang M; Wen Z; Chen Q; Ma Y; Wang X; Wang C; Yin T; Wang X; Lu G; Chen H; Qi J; Yang Y
Eur J Med Chem; 2023 Mar; 249():115166. PubMed ID: 36731272
[TBL] [Abstract][Full Text] [Related]
7. Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway.
Dai Y; Liu Y; Li J; Jin M; Yang H; Huang G
Bioengineered; 2022 May; 13(5):13906-13918. PubMed ID: 35706397
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase M2 isoform.
Ning X; Qi H; Li R; Jin Y; McNutt MA; Yin Y
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):126-129. PubMed ID: 29185365
[TBL] [Abstract][Full Text] [Related]
9. Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis.
Zhao X; Zhu Y; Hu J; Jiang L; Li L; Jia S; Zen K
Sci Rep; 2018 Sep; 8(1):14517. PubMed ID: 30266938
[TBL] [Abstract][Full Text] [Related]
10. SYUNZ-16, a newly synthesized alkannin derivative, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of AKT/FOXO signal pathway.
Deng R; Tang J; Xie BF; Feng GK; Huang YH; Liu ZC; Zhu XF
Int J Cancer; 2010 Jul; 127(1):220-9. PubMed ID: 19904742
[TBL] [Abstract][Full Text] [Related]
11. Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell Lines In Vitro.
Yuan S; Qiao T; Zhuang X; Chen W; Xing N; Zhang Q
Yonsei Med J; 2016 Nov; 57(6):1312-23. PubMed ID: 27593857
[TBL] [Abstract][Full Text] [Related]
12. Identification of a new pyruvate kinase M2 isoform (PKM2) activator for the treatment of non-small-cell lung cancer (NSCLC).
Li RZ; Fan XX; Shi DF; Zhu GY; Wang YW; Luo LX; Pan HD; Yao XJ; Leung EL; Liu L
Chem Biol Drug Des; 2018 Nov; 92(5):1851-1858. PubMed ID: 29931766
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological activity evaluation of podophyllotoxin-linked bile acid derivatives as potential anti-liver cancer agents.
Cai DS; Lou SY; Huo S; Yang YQ; Gao F; Pi WM; Chen KD; Wang C; Yang XY; Jiao JY; Xu B; Wang PL; Lei HM
Bioorg Chem; 2022 Nov; 128():106066. PubMed ID: 35964500
[TBL] [Abstract][Full Text] [Related]
14. Antitumor Activities of the Novel Isosteviol Derivative 10C Against Liver Cancer.
Malki A; El-Sharkawy A; El Syaed M; Bergmeier S
Anticancer Res; 2017 Apr; 37(4):1591-1601. PubMed ID: 28373419
[TBL] [Abstract][Full Text] [Related]
15. Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity.
Li XY; Zhang TJ; Kamara MO; Lu GQ; Xu HL; Wang DP; Meng FH
Cell Death Dis; 2019 Jul; 10(7):532. PubMed ID: 31296849
[TBL] [Abstract][Full Text] [Related]
16. Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis.
Shan S; Shi J; Yang P; Jia B; Wu H; Zhang X; Li Z
J Agric Food Chem; 2017 Sep; 65(37):8136-8144. PubMed ID: 28829588
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and evaluation of novel alkannin and shikonin oxime derivatives as potent antitumor agents.
Wang R; Zhang X; Song H; Zhou S; Li S
Bioorg Med Chem Lett; 2014 Sep; 24(17):4304-7. PubMed ID: 25127868
[TBL] [Abstract][Full Text] [Related]
18. A novel small-molecule PI3K/Akt signaling inhibitor, W934, exhibits potent antitumor efficacy in A549 non-small-cell lung cancer.
Wang J; Wang HY; Shen Y; Liang D; Wang HY; Zhang SQ; Cao YX; Cao L
Anticancer Drugs; 2019 Oct; 30(9):900-908. PubMed ID: 30913062
[TBL] [Abstract][Full Text] [Related]
19. DMAKO-20 as a New Multitarget Anticancer Prodrug Activated by the Tumor Specific CYP1B1 Enzyme.
Cui J; Zhang X; Huang G; Zhang Q; Dong J; Sun G; Meng Q; Li S
Mol Pharm; 2019 Jan; 16(1):409-421. PubMed ID: 30481041
[TBL] [Abstract][Full Text] [Related]
20. Anti-tumor effects and mechanism of GA-13315, a novel gibberellin derivative, in human lung adenocarcinoma: an in vitro and in vivo study.
Xie L; Chen Y; Chen J; Zhang H; Liao Y; Zhou Y; Zhou L; Qing C
Cell Mol Biol Lett; 2019; 24():6. PubMed ID: 30651744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
